organic and bioorganic chemistry, peptide chemistry, photochemistry
Joined March 2019
- Tweets50
- Following39
- Followers191
- Likes31
VanVeller Group retweeted
Amidines are an isostere of the amide bond but are unexplored in peptide secondary structure.
The @vanvellergroup from @IowaStateU shows how amidines are not only tolerated in helical structures but can even enhance helical folds. #MyFirstChemSci
doi.org/10.1039/D4SC06108J
Congratulations to our 4th year grad student @emilyob51 for her acceptance into the Iowa State Graduate College Emerging Leaders Academy! 🎉 @ISUGradCollege @IASTATE_Chem
VanVeller Group retweeted
General Installation of (4H)-Imidazolone cis-Amide Bioisosteres Along the Peptide Backbone | Journal of the American Chemical Society @brettvanveller
@IASTATE_Chem #Imidazolone #Amide #Bioisosteres #Peptide pubs.acs.org/doi/10.1021/jac…
Congrats to Moha, Aaron, Emily, and Brendan on their well-deserved graduate student research awards!
A rapid amidine cyclization enables insertion of (4H)-imidazolones––a cis-amide bioisostere––into peptides during SPPS – out now in JACS! 🧪
pubs.acs.org/doi/10.1021/jac…
What can't the thioimidate do? Check out our most article in @JOC_OL on thioimidate solutions to thionopeptide deprotection!
pubs.acs.org/doi/full/10.102…
VanVeller Group retweeted
Our department is hiring an assist/assoc prof in organic chemistry, broadly defined. #chemistry #chem #chemtwitter Please apply isu.wd1.myworkdayjobs.com/Io…
VanVeller Group retweeted
Sulfenamides are an often-ignored functional group due to their instability. A new computational study in #JOrgChem of the α-effect for S–N nucleophiles reveals that an unusual anomeric interaction may aid their stability. From @vanvellergroup, pubs.acs.org/doi/10.1021/acs…
VanVeller Group retweeted
SESSION 4: PROTEIN ARCHITECTURES – STRUCTURE AND FUNCTION
L20 – Brett VanVeller, Iowa State University
Thioimidates: An Obscure Functional Group Provides General Access to Peptide Bond Isosteres
VanVeller Group retweeted
Special moment when you get to present in the same section as your former advisor Ronald Raines at APS #peptides2023. Working on some polymer projects to complete the set with @SwagerGroup and @AdronovGroup
It’s award ceremony season and our lab recently celebrated grad students @brendanxwall and @emilyob51 on their @IASTATE_Chem departmental awards!
Of course they had to get a picture with Rosalind too! 🧬
VanVeller Group retweeted
AGENDA HIGHLIGHT Session 4: Protein Architectures: Structure and Function featuring Ronald Raines, Emma Watson @Dr_EmmaWatson, Brett VanVeller @brettvanveller, Marina Rubini @TheRubiniGroup, and Jianfeng Cai. aps2023.org/
'Early bird' discount ends May 1. #Peptides2023
Our work on amidines in peptides is highlighted by Org. Process Res. Dev. pubs.acs.org/doi/10.1021/acs…
VanVeller Group retweeted
"The synthetic strategy developed in this study represents the first robust and general procedure for the introduction of amidines into the peptide backbone."
Now in @J_A_C_S, from VanVeller and colleagues @IowaStateU
pubs.acs.org/doi/10.1021/jac…
#unnatural
#peptide
#synthesis
VanVeller Group retweeted
A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone @brettvanveller @IowaStateU #Modification #Amidine #Peptide #Backbone pubs.acs.org/doi/10.1021/jac…
VanVeller Group retweeted
Check out this ACS As Soon As Publishable (ASAP) article from @J_A_C_S: A General Strategy to Install Amidine Functional Groups Along the Peptide Backbone. Discover more ASAP articles: go.acs.org/31j
Taking amidines where no amidine has gone before…linear peptides during SPPS! 🚀 @IASTATE_Chem pubs.acs.org/doi/10.1021/jac…