Asst. Prof. of Dermatology @HopkinsMedicine. We study immune responses during skin infections and inflammatory diseases to develop novel immunotherapies
Baltimore, Maryland
Joined April 2022
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Nathan Archer retweeted
Lung inflammation in patients with #eczema may be caused by a tissue-specific immune response to S. aureus, a common skin microbe. The recent @CellReports study led by @ArcherLab and @HopkinsMedicine researchers links eczema, S. aureus, and asthma. sciencedirect.com/science/ar….
Want to learn more about #biofilms and how they evade #antimicrobial killing or host #immunity? Please join us for the 3rd Shirtliff Biofilm Symposium on June 13th in Philly! Sign up below.
markshirtliffbiofilmfoundati…
Shout to @Jen_M_Wu and Laine Feller for representing @ArcherLab at the Gram+ Pathogens meeting. Both gave excellent talks on host responses to S. aureus #skin #infections and #inflammation. #ProudPI @HopkinsMedicine #dermatology
I am excited to share that we received a Serendipity Grant from the @LEOFondet to study the role of adipocytes in #skin #inflammation. This is important, as obesity is linked to increased susceptibility of developing atopic dermatitis and psoriasis.
leo-foundation.org/en/2024/1…
Nathan Archer retweeted
🔔Extended Submission Deadline!🔔
Due to popular demand, the Research Topic: "From Bench to Clinic: Novel Vaccines and Therapeutics – “Success Stories” is extended!
Edited by: Prof. Nathan K. Archer, and Dr. Aru Venkatasubramaniam
NEW Deadline: 27th Sept 2024
👉Get involved: fro.ntiers.in/LgHH
Nathan Archer retweeted
Excited to share this publication by my MD/PhD student @ZachVanRoy on the complex roles of TNF during S. aureus craniotomy infection. pubmed.ncbi.nlm.nih.gov/3904… @UNMC_mdphd @UNMC_PathMicro #ProudPI
Nathan Archer retweeted
Very proud of this latest work from the lab! As we suspected, the immune imprint from a lifetimes exposure to S. aureus might be the reason vaccine have continually failed to drive protective immunity.
The @McLoughlin_Lab and team @tcdbi report IL-10 inhibition during vaccination against #Staphylococcus aureus improves #vaccine efficacy and indicates that nasal colonization influences systemic T-cell responses: buff.ly/3Wn2lss
#Immunology
Nathan Archer retweeted
Thankful for our ongoing collaboration with Drs. Kevin Garvin and Curtis Hartman to examine immune responses in patients with prosthetic joint infection in @jclinicalinvest . Study led by @aru_prabhakar and Chris Horn #biofilm
doi.org/10.1172/JCI174051
Excellent research by Tammy Kielian, @UNMC_PathMicro professor, and collaborators at @unmc and @NorthwesternU
Researchers explore treatment for biofilm infections unmc.edu/newsroom/2024/07/12…
Nathan Archer retweeted
Our most recent work on naRNA, a novel #Neutrophil extracellular trap (NET) component propagating #inflammation via NLRP3 #inflammasome is now out at #EMBO Reports 👉 embopress.org/doi/full/10.10…
Want to learn more about how S. aureus proteases promote skin #inflammation? Check out this review by @sabostars @JennySaito12 from @HopkinsMedicine.
#dermtwitter
liebertpub.com/doi/10.1089/d…
Nathan Archer retweeted
Excited to share this preprint describing a bacterial single-cell RNA-seq platform to interrogate biofilm heterogeneity and transcriptional adaptations following immune cell exposure. Great work by @LKorshoj! #Biofilm @UNMC_PathMicro
biorxiv.org/content/10.1101/…
Nathan Archer retweeted
Host stress drives tolerance & persistence: The bane of anti-microbial therapeutics
@SophieHelaine @theconlonlab @DavisLabJHU & Russell @cornellvet discuss pathways that promote antibiotic recalcitrance of M.tuberculosis, S.aureus, S.enterica & Yersiniae cell.com/cell-host-microbe/f…
Congrats to Yu Wang @HopkinsMedicine and @IBT_inc on study to develop dry formulations of the #Saureus #vaccine IBT-V02, which were effective against strains from around the world and may have utility in countries where cold storage is scarce. 👇
frontiersin.org/journals/imm…
Nathan Archer retweeted
.@KellenCavagnero, Gallo et al. @UCSDHealth use single-cell transcriptomics to identify dermal immune acting #fibroblast (IAF) subsets that communicate with #neutrophils during type 17 #inflammation. hubs.la/Q02m58qV0
#InnateImmunity
Nathan Archer retweeted
Hot off the press, a comprehensive discussion of how Staphylococcus aureus exploits human proteins to persist as biofilm-associated infections. academic.oup.com/femsre/arti… @Horswill_Lab
Nathan Archer retweeted
1/11 Ever wondered why men have more S. aureus infections than women? Check out how testosterone stimulates S. aureus through activation of quorum sensing in our @harristryonlab preprint. Led by M. Sindhura John PhD @UTSWDerm. A #microbiome #staph#mrsa🧵
biorxiv.org/content/10.1101/…
Nathan Archer retweeted
Featured Article: Neonatal microbial-skin crosstalk shapes allergic inflammation. Early postnatal colonization w/skin #microbiota, esp. IAld-producing #Staphylococcus, induces ILC2 priming by TSLP that promotes allergic skin inflammation in adulthood cell.com/cell-host-microbe/a…
Nathan Archer retweeted
NEW Review of the immune response to bacterial T cell superantigens
bit.ly/3vAotEB
by @Superantigens @StephenTuffs @karine_dufresne @aanchal_rishi1 and @nickw_10
summarizing the expanding family of SAgs and their roles in multiple human diseases
Nathan Archer retweeted
Happy to share our recent work let by postdoc @verenalink published today in @NatureMedicine. 👩🔬🥳Ketogenic and vegan diet differentially impact human immune system, microbiome and metabolism. (1/7) 🧵👇
nature.com/articles/s41591-0…
Nathan Archer retweeted
#NeutrophilPower! @ImmunityCP is on 🔥 today! Dong &co show that an alternative population of neutrophils produces the #neuropeptide FF that signals via a GPCR & inhibits #interferon gamma signaling in bystander neutrophils, balancing #lung tissue damage! doi.org/10.1016/j.immuni.202… – at Brookline, MA