Born in Miami, living and working in Gainesville - Love: live music, weightlifting, running, gardening and zen.
Gainesville, FL
Joined June 2009
- Tweets4.1K
- Following813
- Followers278
- Likes4K
Benjamin Markus retweeted
Get some…
@GatorsFB
Benjamin Markus retweeted
Dr. Jack Kruse, a board-certified neurosurgeon, gives a shocking explanation of why the sun—not food—is what controls blood sugar, mitochondria, and the risk of diabetes.
And here are 10 shocking things he revealed:👇
1. The sun changes how your body handles blood sugar.
Benjamin Markus retweeted
Metabolism is downstream circadian effects. Saying of believing that OA is a metabolic disease is food guru myopia. A cursory review of the literature will show this effect.
Here is what you should know:
1. Core clock genes like Bmal1 and Clock DIRECTLY regulate cellular energy production. This includes the glucagon gene on chromosome two where GLP1 actions begin. When these genes are dysregulated by altered light/dark/temperature in your environment this destroys the circadian mechanism and as a result, chondrocytes lose their ability to efficiently produce energy, shifting from healthy oxidative phosphorylation to less efficient glycolysis.
2. Research funded by BigHarma (this paper Lufkin is touting) will try to suggests to the smooth brainer that semaglutide doesn't just work through weight loss; it MAY directly "repair" this metabolic failure in cartilage. This is not true. It is a bypass that comes with consequences the paper never reports.
Anyone who has researched these drugs know they activate the GLP-1R-AMPK-PFKFB3 axis, which FORCES chondrocytes back into an oxidative phosphorylation state, effectively restoring the energy balance that the circadian clock is supposed to maintain.
So what is the key to understanding this paper? GLP1 agonist makes you metabolism step on the gas pedal while blocking engine exhaust from mitochodnrial matrix. This leads to altered and chaotic IMJs and early heteroplasmy in those who FORCE their metabolism to do something the clock genes cannot do because of later light/dark/temperature signals from your choices.
If you want age fast and die sooner but have improved collagen then this is what should be in the advertisement for these drugs, BUT ISN'T. These drugs are dangerous for anyone who can read.
My thesis explains all of this. When you have bad RPE-SCN timing your collagen and weight will be altered. Circadian disruption causes ALL these systemic metabolic issues, because LIGHT is upstream of all the biochemistry. Metabolic dysfunctiuon is a term unwise MDs use who do not know enough about the biophysics of circadian biology. Alteration of the melanin/water semiconductors in the RPE destroys the peripheral clocks in your joints, creating a vicious cycle of cartilage degradation. The best way to fix it and not age faster and die sooner is to get into the sun every day, grounded, and turn off all lights at sunset.
I used to teach that osteoarthritis was "wear and tear" — lose weight, take painkillers, wait for a knee replacement.
A study just published in Cell Metabolism proved that wrong.
Semaglutide (Ozempic) didn't just reduce joint pain in osteoarthritis patients — it reversed cartilage damage.
MRI showed new cartilage growth in weight-bearing knee areas after just 24 weeks.
The key finding: this wasn't about weight loss.
Pair-fed mice that lost the same weight showed zero cartilage protection. Semaglutide appears to work by reprogramming chondrocyte metabolism — switching cells from inefficient glycolysis (2 ATP) to oxidative phosphorylation (up to 36 ATP).
Translation: it's a metabolic fix, not a mechanical one.
Osteoarthritis affects 600 million people. We've been treating it as a structural problem. It's a metabolic one.
Full breakdown coming on the Health Longevity Secrets podcast.
#GLP1 #Ozempic #Osteoarthritis #MetabolicHealth #Longevity
Source:
sciencealert.com/semaglutide…
Benjamin Markus retweeted
Answering the latest Untethered Q&A and I got to this question. Figured it would be good to answer here:
You say you want to have a version of the life I have created. What are the small steps you can take right now to have "a version of that version"? I started really hunkering down when I was 44. I had a wife, two small children, and a dream. No money. My thought was that as long as I looked after my wife and kids, spent time with them, worked diligently on my business plan, any amount of success I could accomplish was "a version of the grander vision."
From there, each version became a little more secure, a little more gratifying.
I had my first million dollar year when I was 47. I thought "if this is all there is, I will be a happy man. A family, a job I love, income and security." And most importantly, I was staying true to myself. Did not feel like I was compromising in any way. Did not feel like I was cow towing, capitulating, or ignoring my moral compass, etc.
In my 50s, I had a beautiful house in Malibu, my same wonderful family, even more money, even more security. That would have been enough. I mean it. But then, at the age of 61 I started primal Kitchen. It took off like nothing I could have ever imagined. Within a few years, I sold it for $200 million. Just another version of the original vision.
Every morning, when I wake up and I look at myself in the mirror as I'm shaving, I think to myself: If everything stopped today would I be content, would I be happy with whatever accomplished, would I be proud of what I've done in my career, would I feel as if I had represented my authentic self, would I be confident that I had done the best I could with my family? Any answer is, yes, of course. It is always perfect.
And that has always been my answer to that question. More might be better, but I am good now.
Benjamin Markus retweeted
This is big.
Back when we all started with this Primal/paleo/real food stuff 20 years ago, did you ever think you'd see these words and phrases and recommendations in the USDA dietary guidelines?
"Nutrient-dense"
"Healthy fats from whole foods... eggs, seafood, meats, full-fat dairy..."
"1.2-1.6 grams per kg" of protein
"Colorful" fruits and vegetables
"traditionally prepared" grains...
"oats, rice, and sourdough preferred"
They even cut way back on grains. 2-4 servings of whole grains down from 8-11 in the old guidelines
There's no mention of seed/vegetable oils, but the implication is that they should be avoided
These are big wins.
Benjamin Markus retweeted
WHY IS SUNRISE IMPORTANT YOU ASK?
Here's one reason your centralized doctors never explain to you.
Your #circadianrhythm is set hardest when you see morning light earliest. When you start missing strong early morning light, your body clocks run late which means you can't fall asleep as well or wake up as easy. Essentially your sleep quality and/or time declines.
What happens next?
#cancer
This study shows the cancer rates between people who live on the EAST side of a time zone compared to cancer rates of people who live on the WEST side of a time zone. Realize that on the east side, the sun RISES much earlier for the same social time. The west may not be the best.
Here's what they found:
When the sun rises later (or I suspect when you miss that bright early morning light) cancer rates rise because heme proteins cannot make enough DDW from CCO.
Women get 3.7% more breast cancer, 16% more esophageal cancer, 4.5% more colorectal cancer, 4.6% more lung cancer, and 10% more uterine cancer.
Men get 9% more stomach cancer, 11% more liver cancer, 4% more prostate cancer, and 13% more leukemia.
If you want good health, start with setting that strong sun signal every day. Sunrise makes CCO make DDW.
aacrjournals.org/cebp/articl…
Benjamin Markus retweeted
My mental clarity has sky rocketed ever since AI told me to physically write more.
There is something ironic that thing we are trying to use to completely automate our lives is telling us to pick up the pen and paper.
Writing is a super power.
Prompts that changed my life. Part 17
Benjamin Markus retweeted
ALL CHRONIC DISEASES = lack of solar redox during daytime while having too much ALAN/nnEMF at day/night.
Oh so you still think sunglasses, clothing, LED lighting, and sunscreen are good modern human ideas that don't affect the SCN or peripheral clocks in your cells? Consider nature's lessons carefully. What does full spectrum sunlight destroy naturally? UVA and B light naturally lowers adrenalin (the stress hormone of the sympathetic nervous system) while its photons re-zip collagen that cortisol release causes at 4AM that wakes us up by allowing water flows to occur between glial cells and neurons via the aquaporin 4 gates in the brain. AM sunrise light has no UVA or UVB present initially. It has blue, green, and red present. It has more blue than any other part of the spectrum and this is stimulatory to waking us up. Naturally, UVA light shows up later in the AM, depending upon your location in latitude, and this frequency of UVA light acts to begin to re-zip the collagen in our skin and eyes. That initial blue light stimulus from the sun’s rise is used to unwind our collagen to increase water flows to stretch the interspaces in neurons to wake our body and mind up at dawn from sleep. The aquaporin 4 gates are what are destroyed in Multiple sclerosis, which is another autoimmune condition.
When we are missing UV and/or IR light for any reason, these photoelectric and photochemical are not made. When full spectrum sunlight is absent in someone who is chronically stressed for any reason, sleep cannot be induced by the adenosine chemical signal from the hypocretin neurons because the incident light signal of blue blocks it. What else blocks cellular regeneration by circadian de-coupling? Lack of full spectrum solar exposure is the most common reason and most overlooked issue in all of medicine these days. Proper ocular melatonin cycle requires that these two frequencies (UV/IR) of light be present to stimulate the regeneration processes in the eye during daytime. It also requires ABSENCE of blue 400-465nm at sunset!!!! When these things are off the result always = INFLAMMATION = too many protons and/or not enough electrons at the mitochondrial cellular level. If you think about your childhood, when you spent the day at the park of the beach, you might remember how easy it was to fall asleep and get a sunburn. The reason is simple, sunlight induces sleep because the regeneration pathways that use melanopsin need daylight to regenerate. When you did fall asleep, the redness of your skin did not come from the thermal burn, but it was from the increased blood flow due to the release of nitric oxide that acted to bring the arterioles of the dermis layers to the surface. This is a natural photochemical change induced by sunlight to allow the skin to absorb the UVA and UVB light at the surface. UVA and UVB light does not penetrate deep. To absorb the UV light we need the circulatory system to come from the dermis because UV light does not penetrate skin more than a millimeter. The NO engorges and vasodilates the arterioles containing the RBC’s. The RBC’s are filled with hemoglobin and porphyrins that absorb both UV and IR frequencies. Form meets function photoelectrically. The sunburn is really an absorption of too much thermal IR energy. It is a time phenomena not a sun phenomena based upon your sun callus and skin type. Deep sunburns can result from several factors: excessive sun, or thin skin, thick skin, or a poor adaptation to seasonal light due to chronic use of UV blocking makeup, clothing, or sunblock use in strong light cycles. Today we bury the sunlight and live under alien sun's at night and get diseases caused by inflammation. The sun is not the cause of our problems..........no matter the paradigm's belief or your own.
Sunlight is a gift of Nature.
UVB = Vitamin D
UVB = Sex steroid off-switch
UVB = Melanin production/fecundity/fertility
UVB = β-Endorphins production
UVB = Analgesic
UVB = Leptin Sensitivity via adiponectin/placenta
UVB = Weight-Loss/satiety/appetite regulation
UVB = Anti-Viral/fungal & Anti-Bacterial/mold
UVA = Nitric Oxide = Blood Pressure Regulation
Controls stems depots for Acetyl choline neuron regeneration, weight loss
IRA = Melatonin Production
IRA = Photoprevention vs Sunburn
IRA = Builds coherent water domains
IRA = Anti-inflammatory lowers pain
IRA = Builds Collagen/piezoelectric
Red Light = Mitochondrial Function, H20, CO2 NO production
Red Light = Reduces Blood Clotting
Blue Light = Circadian Health (morning)
Blue Light = Stimulates stem cell programming
Blue Light = Adipose Regulation with IR-A and UV
Benjamin Markus retweeted
Biggest lessons from my 20s:
1. everything popular is wrong. you need to be comfortable looking weird and swimming against the tide if you want to be happy and healthy today
2. stop trying to be the best. be the only. go all in on what makes you weird and unique
3. use your free time to build the life you want, not escape the life you have. i was working a job i despised, but instead of drinking every night, i'd come home and read books, teach myself to code, learn to market, apply for new jobs.
4. energy is everything. you cannot make creative, life changing decisions if you're sick. improve your health and everything else will start to fall into place
5. most of your "friends" aren't really friends. they're drinking buddies and groups you fell into out of convenience. they don't want you to be your best, they want you to be like them. you need to stop listening to these people if you want to break free and find people you're truly aligned with instead.
6. get a mentor, a therapist, or a close confidant who truly wants what is best for you and you can bounce all your ideas off of. nothing will change your life more than this loving guidance
7. no woman, no job, no location, no amount of money will save you. true fulfillment is 100% internal. rather than trying to change every little thing around you, change your inner world and the outer world will follow
8. learn to cook. it's easier, cheaper, tastier and healthier than eating out.
9. don't chase relationships, chase purpose, raise your T and relationships will start to chase you
10. attention is everything, don't squander it on useless apps and scrolling
11. you're not going to find your soulmate blacked out at 2am at a bar
12. God is not optional. Without a higher purpose in life you will worship a false idol that will ultimately sabotage your health and happiness. Explore widely, read the sacred texts, find a religion that works for you
13. get a hobby that isn't related to work or partying
14. caring too much about health is sickness
15. get a job that allows you to make money from anywhere.
16. it's better to be in the arena getting critiqued than watching on the sidelines. when you put yourself out there you will fail, you will get rejected and condemned. but it's way better than never trying. every critique of you is a cry for help
17. nasal breathe. take off your foot prisons. stop eating seed oils. filter your water. eat meat, fruit and organs. get sunlight. swim in the ocean. sleep deeply
18. say f**k it more. if the only reason not to do something is that you're afraid, do it.
19. spend lots of time in silence. it allows all your sh*t to come to the surface to be released
20. casual sex is a massive waste of time and energy, hurts yourself and other people. you really want love, not fleeting moments of pleasure.
21. everything is working out always...especially the thins that seem like they're not. in hindsight it will all make sense. especially the challenges, failures and pain.
22. orient your life towards becoming your highest, most loving, courageous, freest self instead of trying to find the most comfort and pleasure and then EVERYTHING is a gift, especially the bad sh*t. convince yourself that everything in front of you is a divine gift
23. act as if everything is abundant, coming to you when the time is right. there's no "one person", "one job", "one deal", "one vacation", "one party" you need
24. as cheesy as it is, learn to trust your heart & intuition...if someone or something feels off, it usually is. and if you don't listen, you will be forced to painfully.
25. the greatest skill is learning to learn. find books that interest you, go down weird rabbit holes, learn everything about a subject and share it online.
26. get out of the relationship, leave the city, quit the job if it doesnt feel right...it will be the greatest decision you've ever made, despite how it can feel like being ripped apart at the time
27. stop being so tight assed. have a silly goose time. love deeply. you will die one day, don't worry all your time away.
28. stop trying to get others to approve of you. decide if they're worthy of your approval instead
29. don't run from your emotions, or they'll inevitably come out in more challenging ways. instead, quiet your mind, sit with them, feel into your body and allow them to be there. treat all your pain like it's a younger version of yourself asking to be loved.
30. be very cautious giving your full trust to anybody...especially those that seem like they deserve it most. it's not that people are trying to f you over, but you are the only person that can fully know you...your intuition knows better than any other person.
31. you don't actually want a wife who cannot make money...you want someone who's interesting, beautiful, intelligent and actually capable of supporting herself, but may choose not to once you have kids. look for someone who has religious values (compassion, humility, truth, forgiveness), but isn't dogmatic, and is also capable of surviving in the modern world.
32. everything you fear is actually a boogeyman hiding under the bed...it's not real when you actually look at it.
33. grow out your hair
34. fomo isn't real. if you're not there, you're not meant to be there...and it's prob not worth it anyways.
35. unhappiness is just a story + resistance to the now. you don't need to do anything herculean to find peace. it's always here when you simply get beyond the thought "i don't like this situation right now".
36. sun your balls
31-28 Fins
Final score prediction‼️‼️‼️
Whoever gets it correct i will send you to the next Miami Dolphins home game OR a jersey of your choice 🐬
How to win:
Have to be following @FinsPhanatics
Retweet this tweet 🔁
Comment your prediction 🔥🤌🏼
GOODLUCK! #GoFins
1
80
Benjamin Markus retweeted
20 Fitness Rules for Men & Women Over 40 (Bookmark This)
#1 - Your focus in the gym is injury prevention first and results second. The older you get the more you smarter you must train.
#2 - Stop trying to burn fat with your workouts. Instead, use them to gain muscle. You'll burn more fat by adding more muscle to your frame.
#3 - Keep your movements smooth and controlled. Focus on time under tension to build muscle while avoiding injury.
#4 - Stick with the same workouts for 8 to 16 weeks while using progressive overload to make gains in the gym.
#5 - Start your workouts with a dynamic warm-up using mobility stretches & muscle activation to keep yourself injury-free.
#6 - As you age protein becomes more important. Get at least 1 gram per pound of ideal bodyweight every day.
#7 - Get your bloodwork done every 6 months. You need to know what’s happening under the hood.
#8 - Track your workouts. This may seem annoying at first but you'll find you'll make faster progress doing this than lifting aimlessly at the gym.
#9 - The path to sustainable health is to find a way of eating that works for the body and lifestyle you want to live.
#10 - One of the best ways to live longer is to increase your lung capacity. Find a form of cardio you enjoy and can see yourself doing for a lifetime.
#11 - To optimize your brain and body get at least one hour of sun exposure a day. If you can't do that then supplement with vitamin D3.
#12 - Keep yourself at a healthy body fat percentage. One thing to note is that this number changes as you age and varies based on gender.
#13 - Cardio is how you live a long life. Resistance training is how you live a quality life. Sleep is how you recover and regulate your hormones. Marry all 3 of these together to make a fitness kingdom.
#14 - Attune your lifestyle to the sun and your circadian rhythms. Over time the body becomes its own alarm clock.
#15 - Sleep is the best legal performance-enhancing drug on the planet. Do everything you can to get the hours of sleep you need and work to enhance the quality of your sleep. Use a sleep tracker like an Oura ring or Whoop to measure your improvement.
#16 - Create a habit of walking every day. This is the most underrated exercise for living longer and a better working brain.
#17 - Creatine should be a staple in most people’s supplement cabinets.
#18 - Your workouts should be centered around pillar movements such as the squat, deadlift, bench press, back row, lat pulldown, overhead press, lunge, and carry. Don’t think these are mandatory exercises. Think of them as movements you want to become stronger in.
#19 - Drinking water is one of the most underrated ways to improve your health and body. Drink it.
#20 - Never use age as an excuse. Unless you were a pro athlete you can still become the fittest version of yourself past the age of 40 if you know how to do the right things.
Take these rules with you to the gym and let me know how they go.
If you enjoyed this then follow me @fitfounder for threads like this.
Another fun one for your 10/23 archives:
newspapers.uflib.ufl.edu/UF0…
1
621
