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Canals Lab (@Canals_Lab) profile picture

Canals Lab

@Canals_Lab

Assistant Professor at UZH and Kispi Zurich. Neuroscientist combining iPSCs and genome editing to model human neurodegenerative Lysosomal Storage Disorders.

 Zürich, Switzerland
kispi.uzh.ch/en/forschungszentrum/neurodegenerative-lysosomal-storage-disorders
Joined September 2020
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  • Followers241
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Photo by Canals Lab (@Canals_Lab)Photo by Canals Lab (@Canals_Lab)Photo by Canals Lab (@Canals_Lab)
It’s a great pleasure to share our latest paper on the impact of oxidative stress on newly emerging hematopoietic cells 🧫 Thanks to everyone who contributed, and made it possible. Out now in @jbiolchem 👉 sciencedirect.com/science/ar…
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Happy to have contributed to this study. Wonderful consortium with excellent science, collaboration and people! Congratulations to everyone involved!!
Lukas Valihrach (@LukasValihrach) profile pictureLukas Valihrach@LukasValihrach27 Sep 2024
🎉Excited to share our latest paper in @GLIA_Journal led by my brilliant student @ZMatusova, in collaboration with amazing international partners!🌍 📄 Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease onlinelibrary.wiley.com/doi/… @IBT_CAS @BIOCEV_science
Image from Lukas Valihrach (@LukasValihrach)
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🎉Excited to share our latest paper in @GLIA_Journal led by my brilliant student @ZMatusova, in collaboration with amazing international partners!🌍 📄 Aberrant neurodevelopment in human iPS cell-derived models of Alexander disease onlinelibrary.wiley.com/doi/… @IBT_CAS @BIOCEV_science
Image from Lukas Valihrach (@LukasValihrach)
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What fuels a lifetime of discovery? Prof. Olle Lindvall, a jubilee doctor at @lunduniversity and pioneer in brain repair, reflects on 50 years of neuroscience. Discover his journey from student to neuroscientist and his advice for future researchers ⤵️ stemcellcenter.lu.se/article…

What fuels a lifetime of scientific discovery? Olle Lindvall reflects on his journey in neuroscience

Lund University. Olle Lindvall’s early academic interests did not suggest a future in neuroscience. “Before I took my high school exams," he recalls, "Biology was not on my radar. I was more intere...

stemcellcenter.lu.se
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Next up at #OpenScienceWeek2024 is @bwmol, who will talk about scientific integrity concerns. There are many things that can go wrong in scientific publishing. Clinical trials usually follows certain guidelines - comparing standard treatments to an experimental treatment.
Image from Elisabeth Bik (@MicrobiomDigest)
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Another week another #assembloid system
ACS Nano (@acsnano) profile pictureACS Nano@acsnano20 Sep 2024
Biocompatible two-photon polymerization (TPP) #3D-printed meshed vessels facilitate the dimensional breaking growth of #BrainOrganoids and multiregional #assembloids. #OpenAccess: go.acs.org/aWh
TOC image from the article

ALT TOC image from the article

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And today we could finally start cell lab work in our new iPSC culture room!
Image from Canals Lab (@Canals_Lab)
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Great news!
URPP ITINERARE (@itinerare_uzh) profile pictureURPP ITINERARE@itinerare_uzh13 Sep 2024
Yay! We are overjoyed to announce that the #UZH Universität Zürich has approved the next funding period for the URPP ITINERARE! Thank you all for making this possible!
Image from URPP ITINERARE (@itinerare_uzh)
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Great to have joined the excellent scientific community at ZNZ and present the work our lab does in the ZNZ symposium!
Image from Canals Lab (@Canals_Lab)
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We're hiring a Research Assistant to join our collaborative team! Gain hands-on training in human stem cells and explore the genetic & molecular basis of neurodegenerative and neurodevelopmental diseases. Please share! If you’re interested send your cv to [email protected]
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And since it's #FluorescenceFriday we'd love to share a beautiful image of iPSC-derived astrocytes featured in our new preprint (Green = GFAP, Red = S100B, Blue = DAPI)! Image credit: talented PhD student @alexlish47 😎
Image from Young-Pearse Lab (@YoungPearseLab)
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It's been 6 years that we developed our iAs protocol @AhleniusHenrik and it is really rewarding to see it being used in such an amazing work!
bioRxiv Neuroscience (@biorxiv_neursci) profile picturebioRxiv Neuroscience@biorxiv_neursci31 Jul 2024
Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's ... biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Replying to @AhleniusHenrik @Frenkez
TODAY: Visit poster 224 to chat with Oskar Zetterdahl ( joint PhD student with @Canals_Lab ) about tagging SNCA in iPSCs for tracking aggregation in LSDs
Image from Henrik Ahlenius (@AhleniusHenrik)
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The lab will be at #ISSCR2024. Check out our posters: number 224, 377 and 571. Also, feel free to reach out if you want to chat about reprogramming, disease modeling or anything astrocytes. See you soon!!
Image from Henrik Ahlenius (@AhleniusHenrik)
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If you want to know the outcome of your prime editing experiment before you even conducted the experiment, visit pridict.it Congrats to Nicolas and many thanks to all collaborators @krauthammerlab @bvansteensellab
Nature Biotechnology (@NatureBiotech) profile pictureNature Biotechnology
@NatureBiotech21 Jun 2024
Machine learning prediction of prime editing efficiency across diverse chromatin contexts go.nature.com/3VQNmq9
Image from Nature Biotechnology (@NatureBiotech)
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📢 Hey there, researchers! While you're enjoying that coffee, why not take 5 minutes to share your publishing journey in our quick survey? Help us crack the code of academic publishing 🎲☕ #PeerReview Please share this with your friends and colleagues! gukennczi05.typeform.com/to/…

A short survey on Academic Publishing

Turn data collection into an experience with Typeform. Create beautiful online forms, surveys, quizzes, and so much more. Try it for FREE.

gukennczi05.typeform.com
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Post-Doc opportunity! Interested in cellular reprogramming as a therapeutic option? Join the Bengzon lab in collaboration with us @Lund_Stem to develop Astrocyte reprogramming as a treatment for brain tumors. Apply here: fens.org/careers/job-market/… #postdoc #LundSCC #LUCC
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We are recruting a post-doc! Are you interested in cellular reprogramming and Alzheimer's disease? Then this is for you!! Apply before December 10th: lu.varbi.com/en/what:job/job… Questions? feel free to DM me. @Lund_Stem @MultiparkL #Postdoc #Reprogramming #Astrocytes #Alzheimer

Post doctor within Stem Cells, Aging and Neurodegeneration

Description of the work place The Stem Cells, Aging and Neurodegeneration group is using stem cell, reprogramming and genome engineering technologies to study aging and neurodegeneration. The team is

lu.varbi.com
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Come to Lund! Chris is great!
Christopher Douse (@ch_douse) profile pictureChristopher Douse@ch_douse29 Jun 2023
Replying to @ch_douse
Finally, we are hiring! If you are interested in the repetitive genome/ transposons/ epigenetics/ chromatin/ brain development and fancy living in Scandinavia, get in touch! We are a friendly bunch and Lund even has a transposon-themed running club open for new members. [7/7]
Image from Christopher Douse (@ch_douse)
Image from Christopher Douse (@ch_douse)
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