Vignesh Ganapathi-Subramanian (@Chappli) header
Vignesh Ganapathi-Subramanian (@Chappli) profile picture

Distorting reality.

Sunnyvale
Joined September 2009
Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)Photo by Vignesh Ganapathi-Subramanian (@Chappli)
Vignesh Ganapathi-Subramanian retweeted
Joy Milne, a retired nurse from Scotland, first noticed a distinct, subtle "musky" smell on her husband, Les, about 10 to 12 years before he was officially diagnosed with Parkinson’s disease in 1994. At the time, she didn't connect the odor to any medical condition, assuming it was just sweat or a change in his body chemistry. It wasn't until years later, when attending a Parkinson's support group with Les, that Joy realized every person in the room shared that exact same distinct scent, prompting her to believe that Parkinson's disease carried a unique olfactory signature. Intrigued by her claim, researchers at the University of Edinburgh, led by Dr. Tilo Kunath, decided to test Joy's ability through a double-blind study. Joy was given 12 plain T-shirts, six worn by confirmed Parkinson's patients and six worn by healthy control subjects. Joy correctly identified all six Parkinson's patients, but she also insisted that one of the control group members had the disease. Although marked as an error initially, the story took an incredible turn eight months later when that specific control subject was officially diagnosed with Parkinson's, revealing Joy had a 100% accuracy rate and had detected the disease long before clinical symptoms appeared. Joy's extraordinary olfactory sensitivity, a condition known as hyperosmia, led scientists to investigate what compounds she was actually smelling. Researchers discovered that the distinct odor stems from volatile chemical changes in sebum, the oily substance secreted by the skin, which is altered by Parkinson's disease. Joy’s gift has since paved the way for scientists to develop early diagnostic tools, including skin swabs and mass spectrometry tests, aimed at identifying Parkinson’s years before motor symptoms begin. Joy Milne’s incredible olfactory ability extends far beyond Parkinson's disease and it comes at a significant personal cost. Joy is an extreme "super-smeller" due to hyperosmia. Researchers have traveled with her internationally to test her ability to detect other conditions; she has helped scientists conduct preliminary odor research on tuberculosis (TB) in Tanzania, as well as cancer and Alzheimer's disease in the U.S. While her nose is a gift to medical science, Joy has often described her heightened sense of smell as an everyday burden. Everyday environments can be overwhelmingly painful for her. She has to strategically plan her routine, often doing grocery shopping very early in the morning or late at night to avoid the heavy perfumes worn by shoppers, and actively avoiding the household chemical and detergent aisles in supermarkets entirely because the artificial fragrances are so agonizingly intense. #archaeohistories
136
830
79
5,889
709,857
Vignesh Ganapathi-Subramanian retweeted
We quit our jobs. There were six of us — Shiv Nadar, Arjun Malhotra, Yogesh Vaidya, Subhash Arora, D.S. Puri and me. It was 1976. Startups were not really a thing in India. Venture capital did not exist. Banks were not exactly lining up to lend money to six young men with an idea and no collateral. And computers? Most people had barely heard of them. But we believed the microprocessor was going to change the world. So we took the plunge. Between the six of us, we managed to put together ₹1.87 lakh. We borrowed, pooled our savings and, in one case, even sold a car. Our first office was a small barsati in Golf Links, Delhi. We called ourselves Microcomp. We wanted to build an Indian computer. There was just one problem. We didn’t have a manufacturing licence. That eventually led us to UP Electronics Corporation. They had the licence. We had the technology. And that partnership gave birth to Hindustan Computers Limited — HCL. But perhaps the most audacious part of the story was what happened next. We started selling a computer that was still being designed. We had a brochure and a mock-up of the machine. That was it. Our sales teams went across India, knocking on doors and convincing businesses to buy into a technology they had never used before. The first orders came from IIT Kharagpur and IIT Madras. Then came the harder part — convincing businesses. In Coimbatore, we were up against DCM DP, a much bigger and more established name. I still remember sitting in the reception area of Premier Mills while the DCM team made its pitch. We went in second. And we won. That one order gave us five more. Then ten. That was HCL in those early years: not having the biggest balance sheet, the biggest brand or the easiest path — but finding a way. We were restless. We looked for gaps. We hired people who had what we called a “cowboy” spirit. We believed that technology had to be made useful and accessible, not intimidating. And we kept moving. From building India’s early indigenous computers to taking our business to Singapore when HCL was just four years old. From a small room in Delhi to a global technology company. When I look back at 50 years, I think about six people sitting together in 1976, wondering if this crazy idea could actually work. I think about a barsati. A brochure for a computer that did not yet exist. And the courage to knock on the next door. That, to me, is the real HCL story. 50 years later, the technology has changed beyond anything we could have imagined. But the spirit remains the same: Dream big. Take the risk. And above all, Just Aspire. Happy 50th, HCL. What a journey it has been. #AjaiChowdhry #JustAspire #HCL #50yearsofHCL #Nostalgic #Founders
372
1,725
169
9,359
629,111
Vignesh Ganapathi-Subramanian retweeted
I simply can’t take seriously anyone who uses the phrase ‘to have someone on the back foot’ as a derogatory. Cos all I’m thinking is yerr but did you ever watch Tendulkar kiss one through the covers off his tiptoes.
18
38
6
496
32,184
Vignesh Ganapathi-Subramanian retweeted
Went for my high school's 50th year annual day celebrations. Was nice to see Prof. Kamakoti from @iitmadras, the chief guest, honour our chemistry professor, Krishnan sir. 🙌
1
11
577
Vignesh Ganapathi-Subramanian retweeted
1/ Same point in my post, with the mechanism. Math is a “pure thought activity” because the explorer and the referee are the same machine: generate, test, verify, all inside the symbolic world. “The rest of what we do” is harder for one reason. There, nature is the referee.
Fields Medalist Jacob Tsimerman: "math is maybe being hit faster by AI because it's a pure thought activity" AI systems have already solved many important conjectures on their own, and very soon, I think they'll become robustly better at the rest of what we do too
1
1
13
3,289
Vignesh Ganapathi-Subramanian retweeted
Namaste, Ma'am...Aapko 1 story sunata hoon.... In the summer of 1980, a distraught 7th grade boy stood in the courtyard of a modest house in Mylapore, watching his father toss his cricket bat down a deep well. A fast bouncer had shattered the boy's spectacles during a local match & his father, a renowned Sanskrit logician, was terrified for his son's sight. "Your cricket days are done," his father declared, handing him a violin. "If you want to master precision, master this." The boy did not throw a tantrum. He directed his focus toward the strings, training until he was performing alongside musical legends, even taking direct corrections from Bharat Ratna M.S. Subbulakshmi. 5 yrs later, he suffered another blow: he failed to clear the IIT-JEE examination. He did not give up. He enrolled in a regional engineering college, quietly mastering computer science logic gates. He eventually worked his way into IIT Madras as a postgrad researcher, earned a PhD, joined as a prof & eventually became the Director of the very institute that had once turned him away. By 2011, while the world was building consumer mobile apps, this prof was looking at a hidden national vulnerability: every radar, fighter jet, banking server & defense system in India was running on foreign-designed microprocessors. He had a single question in his mind: "We can test that a foreign chip does what we WANT it to do. But can we guarantee it does not do something we DO NOT want it to do when a war starts?" He proposed building a completely indigenous, industrial-grade microprocessor from scratch. Global tech giants insisted it could not be done w/o billions of dollars in infrastructure & massive foreign patents. He did not care. Working out of cramped labs on long shifts, he & his team adopted the open source RISC-V instruction set. They hand-coded logic gates, mapped silicon layouts & verified billions of instruction cycles. In July 2018, a tiny 16mm² piece of silicon codenamed Risecreek arrived back at the lab. The team wired it up, flipped the switch & watched a flickering monitor as the Linux operating system booted on 100% Indian-designed silicon for the 1st time in history. Today, his SHAKTI processor architecture powers everything from defense communications to space grade controllers built in collaboration with ISRO. That young boy whose father threw his cricket bat down a well... The student who missed the JEE list in 1985... The violinist who turned down the official IIT Director's mansion to stay in his family home & protect his late father's Sanskrit library... His name is Prof. Veezhinathan Kamakoti.
555
3,770
285
8,548
471,474
Vignesh Ganapathi-Subramanian retweeted
A tale heard from someone about Sobers who passed away yesterday: Sobers recalls: “I went in to bat in the first innings and Dennis came up with a short-pitched ball. I played a little bit early and Keith Stackpole picked me up at second slip. That evening I went to the dressing room where Ian (Chappell) was sitting and said to him, ‘You’ve got a boy here called Lillee. Every time I have gone in, all I have got from him is bouncers. I want you to tell him that I can bowl quick too, and I can bowl bouncers. So watch out for me when he comes in.” "Lillee came in with the score reading 285 for nine. I bowled this bouncer, and it whizzed past Dennis and he looked at me and he had turned completely pink. I knew by that time that I had got him.” Sobers had gone in to the Australian dressing room yet again and Ian Chappell confided to him, “I’ll tell you something: when Dennis came in, before he reached the room, the bat hit the wall, and he said, ‘That little so-and-so, I will show him. I haven’t really bowled quick at him yet’.” The legendary all-rounder replied, “Well, he’s got the ball, I’ve got the bat. I’ve never met the one who can scare me before, and I don’t think that I will.” CARNAGE! The next day, Sobers came in to bat at 146 for 3. The lead less than fifty and the balance was still tilted well in favour of Australia. Lillee charged up and bowled short. What followed was carnage. Sobers started with a blistering square-cut past point that sped to the fence at a rate almost approaching the speed of light. It set the tone for the day. When the ball was up, he drove — with timing and power beyond the capability of lesser men bound by the limitations of the mortal. When it was short and wide, he cut or drove off the backfoot with a ferocity that was primal in beauty and brutality. And when deliveries came rearing into his body, he rocked back to pull and hook, furious and fearless. Lillee, Bob Massie, Terry Jenner and Kerry O’Keeffe combined into an intimidating attack. All of them were slaughtered with a blade that flashed in a manner both savage and sublime. The fast men were carted all around the wicket. The spinners were driven and lofted with uncanny quickness of eye and feet, and a thorough disdain for their length, line and reputation. Everyone at the ground was aware of an exhibition beyond the ability and dreams of all but that one man on the planet, and there were plenty of great cricketers assembled for the match. The few hours at the crease saw dominance never witnessed before. “I had three men square on the off side for the short delivery, and I remember him driving and cutting repeatedly between them. It was amazing stuff,” recalls Lillee. By the end of the day, he was on 139 and World XI at a respectable 344 for 7. Ian Chappell trudged into the rival dressing room that evening. “I head over in his direction to congratulate him, just the two of us are in a quiet corner, and after I pour him a beer, he has a sip and then says, ‘Prue’s left me.’ Prue being his wife who lived in Melbourne in those days. I said: ‘Sobie, if that’s the bloody thing that’s annoying you so much, give me her phone number, and I’ll tell her to get bloody home straight away.’ You know, he just laughed. And it didn’t make any difference — he came out and belted us again.” The crowd stood as one to applaud each time he reached a milestone — hundred, hundred and fifty, double hundred, two hundred and fifty. And when he finally fell, lofting Greg Chappell down the throat of mid-on, he had scored 254. The Australian fielders clapped him all the way back to the pavilion. Lillee looked at Sobers and said, “I’ve heard about you and now I’ve got my tail cut properly.” Sitting in the stands was the great Don Bradman, who thought it was the greatest innings he had ever seen in Australia. And he had seen quite a lot. #GarySobers #memories
24
171
12
797
63,299
Vignesh Ganapathi-Subramanian retweeted
Locations confirmed for the Sparkle Army Shuttle! 🚌 We're offering fans the chance to get to Oakland Coliseum for FREE with our Sparkle Army Shuttle🦄 To secure a seat, simply register through the link: tr.ee/5O3AsZ #GoCorns
3
1
3
1,163
Vignesh Ganapathi-Subramanian retweeted
ரஜினி ஒருமுறை கமல் பற்றி பேசும் போது நான் தொட்டதெல்லாம் அவரும் தொட்டார் , ஆனா அவர் தொட்டதை நான் தொடல்ல என சொன்னார் . சமகாலத்து உச்ச கலைஞர்களில் இது போல இருவரை பார்க்கலாம் . எம் ஜி ஆர் வகையறா படங்களை சிவாஜி செய்ய முடியும் . ஆனால் ஒரு பாகப்பிரிவினையோ , தில்லானா மோகனம்பாளோ எம் ஜி ஆரால் செய்ய முடியாது . ஜேசுதாஸ் மேதமையைக் காட்டும் வகையான பாடல்களை எஸ் பி பியால் பாட முடியும் . ஆனால் இளமை இதோ இதோ பாடலை ஜேசுதாஸ் பாடினால் சரிப்படாது . அது போல சுசீலா என்ற குயில் பாடிய வகையான பாடல்களை ஜானகியும் எத்தனையோ பாடியிருக்கிறார் . ஆனால் நேத்து ராத்திரி பாடலை சுசீலா பாடினால் சரிப்படாது . நேத்து ராத்திரியும் பாட முடியும் .. மாதா உன் கோவிலில் , சிங்காரவேலனே தேவா வும் பாட முடியும் . ஜானகி ஒரு பெண் எஸ் பி பி . எஸ் பி பி ஒரு ஆண் ஜானகி . “செந்தூரப் பூவே” “அழகிய கண்ணே” “ஊரு சனம் “ “சிப்பி இருக்குது “ “சுந்தரி கண்ணால் ஒரு சேதி” “இஞ்சி இடுப்பழகா” “சுந்தரி நீயும்” “ராசாவே ஒன்ன நம்பி” “மவுனமான நேரம்” பாடகிகளில் சகலகலா வல்லி ஜானகி ! காற்றில் உந்தன் கீதம் எந்நாளும் நிலைத்திருக்கும் !
32
279
8
1,571
51,947
Vignesh Ganapathi-Subramanian retweeted
Show me the footballer who made you fall in love with the game. I'll start:
1,047
250
286
2,977
175,128
Vignesh Ganapathi-Subramanian retweeted
Nelson Type Foundry pioneered typefaces of Dravidian languages, owned by Manickam Mudaliar, who came to be called “Nelson Manickam”, thus the name of the road
Tell me a piece of trivia about your city that you think most people will not know. Here's mine: The official name of Marine Drive in Mumbai is Netaji Subhash Chandra Bose Road.
19
133
8
785
43,939
Vignesh Ganapathi-Subramanian retweeted
I am disappointed with the intensity that people have raised criticism against Ruturaj. Here’s a guy who has won the Orange Cap, spearheaded his side to two IPL title wins, and scored tons across formats for India. These credentials are not as common as you’d think. #IPL2026
49
253
16
2,015
78,083
Vignesh Ganapathi-Subramanian retweeted
Five bowlers in 18 years. That’s how many pass the scrutiny of a statistical test for elite death bowling. Elite bowlers don't bowl more yorkers. They just miss fewer. The yorker: economy 5.4. The full toss: 12.4. Six inches, a world apart. Read more: medium.com/@vishalmisra/five…
12
36
5
220
54,658
Vignesh Ganapathi-Subramanian retweeted
R Ashwin is set to become the first Indian international cricketer to feature in the MLC 🏏 More info: bit.ly/4bDRemw
15
60
4
1,281
29,834
Vignesh Ganapathi-Subramanian retweeted
Class, control, and spin. Ravichandran Ashwin is a Unicorn 🦄✨ Who guessed it? Read more ➡️ bit.ly/4bBTbzM #SFUnicorns #GoCorns @ashwinravi99
9
38
12
578
27,522
Vignesh Ganapathi-Subramanian retweeted
ICT Fans Today. #INDvsNZ
73
1,315
38
17,669
475,233
Vignesh Ganapathi-Subramanian retweeted
Prof. Donald Knuth opened his new paper with "Shock! Shock!" Claude Opus 4.6 had just solved an open problem he'd been working on for weeks — a graph decomposition conjecture from The Art of Computer Programming. He named the paper "Claude's Cycles." 31 explorations. ~1 hour. Knuth read the output, wrote the formal proof, and closed with: "It seems I'll have to revise my opinions about generative AI one of these days." The man who wrote the bible of computer science just said that. In a paper named after an AI. Paper: cs.stanford.edu/~knuth/paper…
143
1,836
311
8,978
1,419,604
Vignesh Ganapathi-Subramanian retweeted
#SFUAIGamechanger of the #INDvWI game in the @T20WorldCup is @IamSanjuSamson. Sanju made the highest score by an Indian in a @T20WorldCup chase, while almost singlehandedly hauling India home in a knockout at the biggest stage. Sign up at sfunicorns.ai for more.
1
1
1
113
Vignesh Ganapathi-Subramanian retweeted
Irrespective of who wins in India vs WI today, this T20 World Cup will have four semifinalists from four different continents. For all the “why call it a World Cup?” rhetoric sparked by that viral map tweet, this hasn’t happened ever in 22 editions of the FIFA Men’s World Cup.
26
422
14
4,434
212,677