Our research group at the University of Ottawa specializes in protein engineering and computational protein design. #proteinengineering #proteindesign
Ottawa, Ontario
Joined November 2017
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Happy to announce our latest publication on #enzymedesign, in collaboration with @MThompsonLab! Check it out in @J_A_C_S:
Design of Efficient Artificial Enzymes Using Crystallographically Enhanced Conformational Sampling pubs.acs.org/doi/full/10.102…
Roberto Chica Lab retweeted
I am very excited to share that our paper led by @erdogananisan, @PouriaDasmeh, @AdrianSerohijos is out @natcomms. It touches key dynamics to understand protein evolution"Neutral Drift" and "Phenotypic Variation" during enzyme/protein evolution.
nature.com/articles/s41467-0…
Roberto Chica Lab retweeted
Come see the scientists that should've shared the Nobel Prize for "Computational Protein Design", speak:
ipd.uw.edu/protein-design-th…
Roberto Chica Lab retweeted
We are recruiting: @ProtEngDesSel is looking for an Editor-in-Chief to lead the journal into the future! If you’re a leader in protein engineering with a strong vision for the field, we want to hear from you.
View more details and apply: oxford.ly/3Y3Hzxg
#JournalEditor
ALT PEDS is now recruiting for a new Editor-in-Chief. Learn more and apply today, featured with the journal's cover.
Roberto Chica Lab retweeted
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Happy to announce the special article collection on computational methods for #ProteinDesign, which I edited for @ProtEngDesSel.
@ProtEngDesSel is excited to share its latest article collection on "Computational Methods for #ProteinDesign". Free to read until Sept. 30, 2024: academic.oup.com/peds/pages/…
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For more information, check out the nice editorial written by @ferruz_noelia and @_amelie_rocks:
academic.oup.com/peds/articl…
Roberto Chica Lab retweeted
We’re thrilled to share our new pre-print exploring how we can design and control dynamic proteins! (1/6) biorxiv.org/content/10.1101/…
Roberto Chica Lab retweeted
Today in @Nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with @CasperGoverde @GoldbachNico @befcorreia 1/6
nature.com/articles/s41586-0…
Roberto Chica Lab retweeted
We investigated AlphaFold3 against RoseTTAfold-AllAtom and a new variant of Metal3D for prediction of metal-protein complexes. Tl;dr AlphaFold3 is as good as specialized tools on metal ion prediction. RFAA not so much.
Some interesting findings in below thread: 1/
Roberto Chica Lab retweeted
An interesting nugget in the latest paper from @MoAlQuraishi lab: AFDB models are less designable in ways that suggest inaccuracies at the local level but not global level arxiv.org/abs/2405.15489
Roberto Chica Lab retweeted
This is a complex discussion that I am hoping will continue well beyond this letter. We need to find standards that work in an increasingly complex landscape of research and publishing, and that balances diverse interests.
We need to find solutions that enable science to ...
We were incredibly disappointed with the lack of code or executable accompanying the publication of AF3 in @Nature . This contradicts scientific principles of the ability to evaluate, use, and build upon existing work. zenodo.org/records/11179894
Abstract submission deadline is April 30th.
More info here:
event.fourwaves.com/pec2024/…
Roberto Chica Lab retweeted
Join us! We are looking for a new team member (PhD student) with strong background in organic chemistry.
Organic chemistry meets #DirectedEvolution
Highly interdisciplinary & passionate research group
🙏RETWEET (We want to recruit internationally)
uni-bielefeld.hr4you.org/job…
Roberto Chica Lab retweeted
Design of Efficient Artificial Enzymes Using Crystallographically Enhanced Conformational Sampling | Journal of the American Chemical Society @ucmerced @uOttawa @Chica_lab @uOttawaScience #Artificial #Enzyme #Crystallographic #Conformational #Sampling pubs.acs.org/doi/10.1021/jac…
Roberto Chica Lab retweeted
Design of Efficient Artificial Enzymes Using Crystallographically Enhanced Conformational Sampling dlvr.it/T4hF25
Roberto Chica Lab retweeted
New article from our "Computational methods for protein design" special collection!
By @CompBioLab_IQCC (@IQCCUdG).
The shortest path method (SPM) webserver for computational enzyme design academic.oup.com/peds/articl…
Roberto Chica Lab retweeted
The 5th Protein Engineering Canada Conference will take place at the University of Toronto on June 26-28, 2024. Speakers include @ltchong @helloanum @chang_c_liu @DavidKwanPhD @casarkar @wenjingwanglab @WeiZhangTO and more! event.fourwaves.com/pec2024
