@ChrisBakerLab

Twitter feed for the Baker Lab at The Jackson Laboratory in Bar Harbor @jacksonlab

 Bar Harbor, ME
jax.org/research-and-faculty/research-labs/the-baker-lab
Joined September 2021
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  • Following115
  • Followers202
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Trainees: apply by January 10th, 2025!
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Registration for #IMGC2025 in Glasgow is open! imgs.org/registration
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🗺️ Explore the potential of pluripotent stem cells at @jacksonlab's workshop, October 21 – 24! Join us for seminars, hands-on method & data analysis workshops, and discussions bridging #Genetics & #StemCell biology: jax.org/education-and-learni… Scholarships available! Learn more ⤵️
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✨ NEW DATES ✨ Explore the potential of pluripotent stem cells at @jacksonlab's interdisciplinary workshop, October 21 – 24! Join us for seminars, hands-on method and data analysis workshops, and discussions bridging #Genetics and #StemCell biology: jax.org/education-and-learni…
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Help us celebrate the 2024 Early Career Community Award recipients 👏 Six early career scientists are recognized for their outstanding work on their respective research organisms: bit.ly/4bqBdOn Don't miss their presentations at #TAGC24: bit.ly/46zzYcX 🧬
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Is the use of #StemCells an important part of your research strategy? ➡️ Check out this interdisciplinary symposium at @jacksonlab, April 29 – May 2: jax.org/education-and-learni… Organizers: @Laura_Reinholdt, @ChrisBakerLab, @martinperaJAX & Ralda Nehme of @BroadInstitute
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Early registration for #TAGC24 closes tomorrow! IMGS members: Don’t forget to check your emails for a discount code! genetics-gsa.org/tagc-2024/r…

Registration - TAGC24

BRINGING GENETICS TOGETHER

genetics-gsa.org
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Join us at #TAGC24 to hear Gary Churchill give the Beverly Paigen Lecture. #Mammalian24
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#IMGC24 at #TAGC24 will have its own "can't miss" keynote talks: Bev Paigen Lecture - Gary Churchill (Jackson Lab) Verne Chapman Lecture - Beverly Mock (NIH/NCI) Mary Lyon Lecture - Clare Smith (Duke University) Inaugural IMGS President's Award - Jason Bubier (Jackson Lab)
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Agenda released! ✅ This #StemCell symposium at @jacksonlab will include sessions about genetic impact on pluripotency; modeling human variants in iPSCs; incorporating diverse genetic backgrounds in research; and applications in high-content screening. jax.org/education-and-learni…
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MAY 23 – 25: This new symposium at @jacksonlab will focus on using genetically diverse panels of murine and human pluripotent #StemCell lines and analyses of genetic heterogeneity, which underlie molecular and cellular phenotypic variability. Learn more: jax.org/education-and-learni…
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Last week we said a bittersweet good bye to #jaxssp2022 with back-to-back research symposia at @jacksonlab in CT and ME. Congratulations and best wishes from all of us @JAX_Education! Don't forget to keep in touch - you all have great things in your futures!
Group photo of SSP students in Bar Harbor.

ALT Group photo of SSP students in Bar Harbor.

Group photo of SSP students in Farmington.

ALT Group photo of SSP students in Farmington.

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🦠 JAX Assistant Professor, Chris Baker, Ph.D., led a bacteriology lab unit at a local elementary school last week. Over the span of three days, Grade 2 students swabbed their hands, grew bacterial colonies and inferred if washing with soap vs. sanitizer was more effective.
Group of young students in white lab coats sitting in a circle on the floor of a classroom as a teacher and a scientist stand at the front of the room talking to the students.

ALT Group of young students in white lab coats sitting in a circle on the floor of a classroom as a teacher and a scientist stand at the front of the room talking to the students.

Group of young students looking at a large screen displaying an image of a petri dish with bacterial colonies. A scientist in a lab coat is pointing to the petri dish.

ALT Group of young students looking at a large screen displaying an image of a petri dish with bacterial colonies. A scientist in a lab coat is pointing to the petri dish.

Two young students wearing white lab coats while swabbing their hands as part of a bacteriology lab classroom unit.

ALT Two young students wearing white lab coats while swabbing their hands as part of a bacteriology lab classroom unit.

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The Baker Lab retweeted
MurawalaLab@PMurawala18 Mar 2022
We are recruiting a second Research Assistant (RA) in our team. Please RT. mdibl.org/careers/research-a…
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Extremely cool insights into the role the #epigenome has on pluripotency. 🔍 Congratulations to everyone who contributed!
The Baker Lab@ChrisBakerLab21 Dec 2021
Very long-awaited, but we're very excited to share Candice Byers’ published work in @embojournal highlighting the impact genetic background has on differentiation bias in mouse embryonic stem cells! 🐁🧬 @jacksonlab @TuftsGSBS tinyurl.com/a6rwp4s9 (a 🧵)
Synopsis of study: We used diverse ESCs and differentiated to EpiLCs and EBs to identify variation in cell state transitions (top). We find that genetically determined chromatin states bias differentiation, with B6 toward neuroectoderm and D2 toward definitive endoderm (middle). Lastly, we used QTL mapping to identify hotspots of trans-regulation of chromatin that impact pluripotency and cell state transitions (bottom).

ALT Synopsis of study: We used diverse ESCs and differentiated to EpiLCs and EBs to identify variation in cell state transitions (top). We find that genetically determined chromatin states bias differentiation, with B6 toward neuroectoderm and D2 toward definitive endoderm (middle). Lastly, we used QTL mapping to identify hotspots of trans-regulation of chromatin that impact pluripotency and cell state transitions (bottom).

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Genetic control of the #pluripotency #epigenome determines differentiation bias in mouse embryonic stem cells #mESCs – Christopher Baker, Candice Byers1 et al @jacksonlab embopress.org/doi/10.15252/e…
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#JAXAlum @ #ABRCMS2021: ➡️Alex: Determining the role of KZFPS in modulating chromatin accessibility and gene expression in mouse embryonic stem cells ➡️Shadae: Uncovering transcriptional changes related to cisplatin treatment and mixing of TNBC subclones using single-cell RNA seq
Graphic showcasing two students presenting ePosters at ABRCMS2021. Text in image: ABRCMS 2021, November 10 – 13, 2021 (virtual). Student ePosters, November 11, 1:55 – 2:40 p.m. ET. Presenter 1: Alex Mora, 2021 JAX Summer Student, Baker lab. Presenter 2: Shadae Nicholas, 2021 JAX Summer Student, Chuang lab.

ALT Graphic showcasing two students presenting ePosters at ABRCMS2021. Text in image: ABRCMS 2021, November 10 – 13, 2021 (virtual). Student ePosters, November 11, 1:55 – 2:40 p.m. ET. Presenter 1: Alex Mora, 2021 JAX Summer Student, Baker lab. Presenter 2: Shadae Nicholas, 2021 JAX Summer Student, Chuang lab.

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Job announcement: We are still looking for a research assistant! This position is perfect for someone with a bachelor's who is interested in reproduction, evolution and/or genomics! @Dumont_Lab DM me if you are interested! Link to the add to follow soon. Please RT 🐭
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We are excited to announce the following 2021 @jacksonlab Summer Student Program participants will be presenting at #ABRCMS2021: 🔹 Gordon Ye (@roelverhaak lab) 🔹 Alex Mora (@ChrisBakerLab) 🔹 Priya Kosana (@EwelinaBolcunF lab) Join us in congratulating these #JAXalum! 🎉
Individual portrait of Gordan Ye, 2021 JAX summer student

ALT Individual portrait of Gordan Ye, 2021 JAX summer student

Individual portrait of Alex Mora Pagen, 2021 JAX summer student

ALT Individual portrait of Alex Mora Pagen, 2021 JAX summer student

Individual portrait of Priya Kosana, 2021 JAX summer student

ALT Individual portrait of Priya Kosana, 2021 JAX summer student

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