
Bringing freedom & autonomy to young people. Built @thielfellowship and @1517fund. First investor @lambdaAPI @loom @Mach_Industries @RainmakerCorp @positron_ai
Bay Area (Oakland!)
Joined April 2008
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I love getting a solid cold email or DM from founders!
No need for an intro to 1517.
Some things will make your message standout and get a response (faster than others)π§΅:
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
We're reaching the point In the singularity where we unlock literal alchemy in the tech tree β at San Francisco, CA
Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERNβs record by a factor of 10.
Last week, we enriched isotopes in the worldβs most powerful plasma centrifuge, beating the Soviet record that stood for 40 years.
Now, weβre building a fusion reactor in San Francisco to achieve record power density.
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
A San Francisco startup says it just turned mercury into real gold, and their own math says gold is one of the cheapest things their machine can make. Aim it at a different metal and it makes a cancer drug ingredient worth tens of billions of dollars a gram.
Here's how it works. When you fuse two kinds of hydrogen, deuterium and tritium, every single reaction kicks out a neutron moving at 14.1 MeV, which is absurdly fast. Fire one into mercury-198 and it knocks another neutron loose on the way through, so two come out and you're left with mercury-197. Give that a few days and it decays into gold-197, the only stable kind of gold there is. The whole trick needs neutrons above about 6 MeV, and regular nuclear reactors barely make those, while fusion makes one every time it fires.
Now swap the mercury for radium-226. Same reaction, one neutron in and two out, and you end up with radium-225, which decays into actinium-225. Novartis is building its next prostate cancer drug around actinium-225, and it's so scarce it sells by the millicurie, roughly $1,200 to $2,500 apiece. Price it by the gram and you're into the tens of billions of dollars, for a material so radioactive nobody could safely hold a gram of it anyway.
Marathon's team actually put a dollar value on a single fusion neutron in a paper this year. Use it to make electricity and it's worth about $3 Γ 10β»Β²β°. Gold comes in at $2.6 Γ 10β»Β²β°, basically a wash. Molybdenum-99, which goes into about 80% of nuclear medicine scans, is worth $2.6 Γ 10β»ΒΉβ· a neutron. Actinium-225 is worth about $10β»ΒΉβ°, around 3 billion times what the electricity's worth.
That's why fusion people should care. Every fusion company you've heard of is chasing electricity, and selling electricity only pays once the plasma puts out something like 10 to 22 times the energy you pump in to heat it. The best result so far, at JET in England, was about a third. Add gold on the side and Marathon's math says you break even around 3x. For molybdenum-99, the number is 0.001x.
So a machine that gives back one-thousandth of the energy you feed it can still make money, as long as the neutrons hit the right metal.
By their numbers, a 3 megawatt machine running way below breakeven could cover the whole world's supply of molybdenum-99, which today comes from splitting uranium in a handful of research reactors. Today's experimental fusion machines already beat the gain that job needs.
Their second post basically says this out loud. Marathon now describes itself as an isotope company for radiopharma. Their chart shows roughly 390 targeted radiotherapy trials. Pluvicto, the prostate cancer drug Novartis launched at $42,500 a dose, did $1.9 billion in sales last year.
Gold still matters to them, just later. It's about a $700 billion a year market, and Marathon's paper figures it could soak up around 2 terawatts of fusion capacity, which is roughly the scale where fusion actually moves the grid. So the plan is to sell cancer isotopes out of small machines now and use gold to pay for the giant ones, years before electricity can pay for itself.
Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERNβs record by a factor of 10.
Last week, we enriched isotopes in the worldβs most powerful plasma centrifuge, beating the Soviet record that stood for 40 years.
Now, weβre building a fusion reactor in San Francisco to achieve record power density.
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Nothing can replace the millennia-enduring allure of alchemy. What an incredible time to be alive.
Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERNβs record by a factor of 10.
Last week, we enriched isotopes in the worldβs most powerful plasma centrifuge, beating the Soviet record that stood for 40 years.
Now, weβre building a fusion reactor in San Francisco to achieve record power density.
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
i honestly think kyle schiller & team are building a generational company, i havenβt been more bullish on a company since cursor or atomic semi
Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERNβs record by a factor of 10.
Last week, we enriched isotopes in the worldβs most powerful plasma centrifuge, beating the Soviet record that stood for 40 years.
Now, weβre building a fusion reactor in San Francisco to achieve record power density.
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Danielle gave a masterclass on how to identify world class talent at the earliest stages
Shoutout to @ADoricko and @RainmakerCorp
Rainmaker
30 days of Hard Tech - Day 12 π§οΈ
Danielle Strachman (GP at 1517):
βAugustus came to us and pitched the idea of literally making God's green earth"
"Augustus is one of the most profound examples we have in the portfolio of hyperfluency... He doesn't just know about the technology, he knows about the history, he knows about the politics. He can speak to any piece of the domain."
"We love pulling the trigger first. Like, it's what we're looking to do... Dog on a leash energy means just that. A dog on a leash does not need more water put down in front of it, more food put down in front of it. It needs the leash to be cut... That energy was very present in Augustus right from the get-go."
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
AI made building software easier than ever. Getting it to actually work inside a business? That's a different story.
Today we're launching @terminalio AI.
A forward deployed engineering team that builds, deploys, and scales AI systems inside real businesses.
More is possible. π
Huge congrats to Xona! Up, up, and away!!
Had the pleasure of meeting Brian very early in the Xona journey and insisted that he needed to talk to Nick @naarnett, our resident space nerd and partner at 1517.
Nick came back excited about the prospects for GPS built for an autonomous world. We wrote the first check into the company of $250K during Fund II. With further progress, we followed on with $495K out of the fund.
In 2022 we put together a $2.5M special purpose vehicle for @XonaSpace in two weeks (the average time our SPVs are open) during their Series A.
Not only are we the first check writer, but we raise special purpose vehicles between $2M - $25M for our founders going the distance to bring additional trusted capital into the company.
We're here for a good time and a long time.
Today, @XonaSpace announced a $250M Series D to accelerate production of its Pulsar commercial GPS constellation, which is aiming to begin service in 2027.
Xonaβs long-term plan is to build a ~258-sat constellation to offer an upgraded commercial alternative to government GPS networks. Xonaβs pitch: GPS is a critical capability underpinning much of the modern economy, but publicly funded GPS networks are costly, complex, and too exposed to spoofing and jamming.
In today's piece, Payload reporter @Douglas__Gorman dives into Xona's plans for the new funds. Link below.
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Thanks for the continued donations $UNICORN ! We are going to use it for making more genetically modified horse embryos on a quest to make real unicorns
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Some say a book is only successful if itβs bought by the 10,000s. But sometimes it only takes one
Replying to @MorganBarrettX
Thank you guys. Iβd like to repost but this is so kind that it would seem vain of me, so Iβll write something separately.
For those that see this reply: 1517 not only wrote rainmakerβs first VC check, but Rainmaker plausibly wouldnβt exist hadnβt it been for @William_Blake βs book. The spark of inspiration that paper belt on fire gave me was instrumental in my initial research and eventual conviction to found @RainmakerCorp .
@DStrachman michael and @zslayback are the best
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Replying to @MorganBarrettX
Thank you guys. Iβd like to repost but this is so kind that it would seem vain of me, so Iβll write something separately.
For those that see this reply: 1517 not only wrote rainmakerβs first VC check, but Rainmaker plausibly wouldnβt exist hadnβt it been for @William_Blake βs book. The spark of inspiration that paper belt on fire gave me was instrumental in my initial research and eventual conviction to found @RainmakerCorp .
@DStrachman michael and @zslayback are the best
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
for all the laws in the world, the only real currency is trust
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Isaac Newton spent decades huffing mercury fumes in a Cambridge cellar, grinding lead into a worthless sludge while praying to the gods of alchemy. Now Marathon can use its reactor blanket to turn mercury-198 into stable gold by the ton. The alchemist will lose to the atom.
Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERNβs record by a factor of 10.
Last week, we enriched isotopes in the worldβs most powerful plasma centrifuge, beating the Soviet record that stood for 40 years.
Now, weβre building a fusion reactor in San Francisco to achieve record power density.
Record setting 1517 founders, now building a fusion reactor in SF!
Last month, we demonstrated high-rate alchemy: turning mercury into real, stable gold, beating CERNβs record by a factor of 10.
Last week, we enriched isotopes in the worldβs most powerful plasma centrifuge, beating the Soviet record that stood for 40 years.
Now, weβre building a fusion reactor in San Francisco to achieve record power density.
Always fun to chat with Morgan!
Rainmaker
30 days of Hard Tech - Day 12 π§οΈ
Danielle Strachman (GP at 1517):
βAugustus came to us and pitched the idea of literally making God's green earth"
"Augustus is one of the most profound examples we have in the portfolio of hyperfluency... He doesn't just know about the technology, he knows about the history, he knows about the politics. He can speak to any piece of the domain."
"We love pulling the trigger first. Like, it's what we're looking to do... Dog on a leash energy means just that. A dog on a leash does not need more water put down in front of it, more food put down in front of it. It needs the leash to be cut... That energy was very present in Augustus right from the get-go."
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
If you're in Massachusetts, you are welcome to our Open House, Saturday 10/24, 1:00 PM. No RSVP needed, but we're glad to know if you're coming:sudburyvalley.org/admissionsβ¦
Can't make the Open House but want to arrange a visit with your child?
sudburyvalley.org/admissionsβ¦
Danielle Strachman π π π πͺ΄ πΈ π¨ π retweeted
Our first genetically selected horse embryos going up for public auction on Sunday! Expecting it to sell for $35k+
Wheely is a really fast stakes broodmare we purchased after we found she had a variant in her growth hormone that could possibly create speed and size advantages



























