Team of brain explorers @Dukenus @ImperialCollege. We study human neural circuit wiring and dysfunction in neuropsychiatric conditions. Tweets by VDP.
Singapore & London
Joined July 2014
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🧠 A rare convergence in Down syndrome research.
Three independent studies across @NatureMedicine & @ScienceMagazine have converged on the same molecular drivers of DS brain development.
A thread on why this matters 🧵👇
(Curated for the Italian T21 Task Force)
6//7 🔭 We are moving from description toward understanding what to target, when, and why.
Step by step, the field is building the foundations for targeted approaches.
Watch this space.
7/7 📚 References: Lattke et al. Nat Med: doi.org/10.1038/s41591-026-0… Vuong et al. Science: doi.org/10.1126/science.aea1… Risgaard et al. Science: doi.org/10.1126/science.aea1… Haydar & Li Science: doi.org/10.1126/science.aeh0…
@NDSS @DSIntl @JeromeLejeune @T21RS @The_MRC @wellcometrust
Single-cell atlas of the developing Down syndrome brain cortex | Nature Medicine Amazing work by Dr Lattke et al @imperialcollege @dukenus #Neuroscience #DownSyndrome #ASO #GeneTherapy #Research #Science nature.com/articles/s41591-0…
Vincenzo De Paola retweeted
Registration for the Ascona 2024 Meeting is now open. Go to asconacircuits.org to submit your abstract and register for the meeting! We are looking forward to seeing you in Switzerland this September! Ascona Meeting Organizers
Vincenzo De Paola retweeted
✨Wishing our community and all our friends a happy holiday season and a wonderful new year! ✨
This festive tree is made out of a microscope shot of neurons in the mouse brain (🔬courtesy of @Sean__OToole, a postdoc in the lab of @georg98keller)
Dear @lufthansa, @lufthansaNews downgrading my 80 year old mum two classes and forcing us to fly 13 hours in separate cabins, because you prioritise selling all your seats, rather than caring for existing customers is deplorable.
As is not receiving any official response, compensation, or apology to our complaint after > 1.5 years. My mum is still recovering from the trauma of flying on her own, when for months she was reassured we would fly TOGETHER, after the forced isolation caused by COVID-19
I hope this horrendous incident can now be resolved by the #LuftfahrtBundesamt, #SÖP, #FederalOfficeJustice and/or #LegalAction
#Flightcancellation, #CustomerServiceNightmare, #FlightComplaint, #UnhappyCustomer
As is your spectacularly unprofessional customer service, exemplified by one of your agents based on the Fiji Islands swearing and giggling, having fun with a colleague, while on the phone with me who tried to explain this was an urgent and serious matter.
Vincenzo De Paola retweeted
If you're interested in understanding how diet can influence the rate of protein aggregation in neurodegeneration, there’s a PhD opportunity with David Klenerman (closes 30th Oct): dementiaresearcher.nihr.ac.u…
Please RT if you think someone in your network might be interested. Thanks!
Well done!
Enjoyed presenting my work at the @dev_neuro Scientific Retreat 2023 at Senate House. Thank you to the organisers, was a fantastic 2 days of engaging scientific discussions. @KingsIoPPN
Vincenzo De Paola retweeted
A perspective by a previous lab member from MTL lab, with which I can say that the current lab members agree.
linkedin.com/pulse/my-first-… – at West Menlo Park, CA
Vincenzo De Paola retweeted
Why is age the main risk for Alzheimer’s disease? Mouse models reveal that the loss of myelin integrity is causally linked to enhanced plaque deposition. Great work by @ConstanzeDepp, @TingSun_MPINAT et al. in Nature nature.com/articles/s41586-0…
