Faculty @icmrnirwoh Developmental biology, infertility, embryo implantation, placentation, sex determination, TEdx speaker. Views expressed are personal

Mumbai, India
Joined November 2009
Deepak Modi retweeted
Bengaluru physicist Ashoke Sen becomes first Indian to win Oskar Klein Medal The string theory pioneer at ICTS joins past medal recipients Stephen Hawking and Peter Higgs, earning global recognition for his contributions to theoretical physics deccanherald.com/science/ben… @ictstifr
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Deepak Modi retweeted
Special Call for Proposals for Establishment of @ICMRDELHI Centre for Advanced Research (CAR) for the Development of Priority Medical Devices and Diagnostic Technologies from top 25 NIRF ranked institutions Details at icmr.gov.in/icmrobject/uploa… Apply by 13th November 2026
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🚨 DAVID M. SABATINI — FROM A POTENTIAL NOBEL LAUREATE TO NEARLY SIX YEARS OF PROFESSIONAL DESTRUCTION AND PERSONAL SUFFERING $6 MILLION IN DAMAGES — BUT WHO CAN RESTORE NEARLY SIX LOST YEARS OF AN EXCEPTIONAL SCIENTIST'S LIFE? @DMSabatini was once among the world's most celebrated biomedical scientists. His pioneering discovery of the mTOR signaling pathway transformed our understanding of cellular growth, metabolism, aging, and cancer. By 2018, he was being discussed as a promising candidate for a future Nobel Prize. In 2020, he received the prestigious Sjöberg Prize from the Royal Swedish Academy of Sciences. Then, his world began to collapse. Late 2020–2021: In October 2020, Kristin Knouse accused Sabatini of sexual harassment. Whitehead then ran an institute-wide climate survey. These steps led to an outside investigation.* * Participation from Sabatini’s lab (~40 people) was low — roughly five responses. Some lab members later said investigators pressured them to give negative accounts. August 20, 2021: The investigation found Sabatini violated Whitehead’s policies on sexual harassment and relationships. He resigned from the Whitehead Institute, was fired by HHMI, and was placed on leave by MIT. April 1, 2022: He resigned from MIT after officials recommended revoking his tenure. Later that month NYU considered hiring him; organized campus protests followed and he withdrew in early May. A scientist who had spent decades building an extraordinary research career was suddenly confronted with professional isolation, public condemnation, lost opportunities, and the dismantling of the institutional foundations supporting his research. The damage extended far beyond his appointments. It consumed years of his life, disrupted his scientific contributions, and subjected him to an ordeal whose personal consequences cannot be measured in financial terms. OCTOBER 16, 2026 — THE VERDICT After nearly six years of controversy and five years of litigation, a Massachusetts civil jury found that his former colleague, Kristin Knouse, had DEFAMED HIM AND TORTIOUSLY INTERFERED WITH HIS PROFESSIONAL RELATIONSHIPS, rejected her counterclaims, and awarded Sabatini $6 MILLION IN DAMAGES, with additional interest. His first public reaction was devastating in its simplicity: “Today I smiled for real for the first time in more than 5 years.” ⚠️ SIX MILLION DOLLARS? What monetary award can compensate for nearly six years of suffering, professional exclusion, shattered opportunities, and the interruption of a potentially Nobel Prize–winning scientific career? Money cannot return lost years. It cannot undo the anguish. It cannot recreate the discoveries that might have been made, the students who might have been trained, or the scientific advances that might have emerged. 🔱 SCIENCEGUARDIANS™ — THE ANATOMY OF A COORDINATED REPUTATION-DESTRUCTION CAMPAIGN Between May 25 and 31, 2026, ScienceGuardians™ published its seven-part investigative series exposing the mechanisms through which academic leaders can be subjected to systematic reputation destruction (🔗 see the link to the full investigative thread in the first comment): Target Selection → Recruitment of Insiders → Weaponization of Partial Truths → Media Amplification → Institutional Pressure → Reputation Collapse → Forced Resignation. The chronology of Sabatini's ordeal reveals disturbing parallels with all seven stages of the coordinated reputation-destruction framework exposed by ScienceGuardians™. For years, ScienceGuardians™ has been investigating the activities of the perpetrators we have identified within the PubPeer “PubSmear” Network Mob, alongside the damaging role that reckless or compromised journalists and editors can play in academic reputation-destruction campaigns. We are examining the extent to which these external actors contributed to the public narratives and institutional pressures surrounding Sabatini's case. Their specific involvement and any coordination must be established through documentary evidence, and our investigation will continue to scrutinize these questions. ⚠️ Malicious reputation attacks and compromised journalism are among the gravest threats to academic integrity. When allegations are amplified without sufficient scrutiny, the resulting institutional consequences can become irreversible long before the underlying facts are fully tested. The Sabatini verdict is a powerful reminder that accusations are not convictions, public condemnation is not due process, and reputational destruction is not scientific integrity. We stand firmly for the right of every scientist to fair treatment, independent scrutiny of allegations, and meaningful accountability when defamation is established. David M. Sabatini has won a significant legal victory. But no jury can give him nearly six years of his life back—or restore to humanity the invaluable scientific contributions he might have made during those lost years. @SciGuardians 🔱
Today I smiled for real for the first time in more than 5 years. Thank you to the jury, judge, court officer and clerk. And of course to my rockstar legal team. I truly wish the best for everyone involved.
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Deepak Modi retweeted
Replying to @DMSabatini
@DMSabatini was always kind, professional, and supportive towards me and my lab. He asked great questions in my faculty meetings that I still remember and we still work on :) He retweeted our work when we needed it the most , and told me about the @PershingSqFdn and other funding sources. I just want to say thank you for that support.
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Deepak Modi retweeted
Tusharika Kotra (Registration No. 10BB21A37016) Ph.D. student of AcSIR will defend thesis entitled “NLRP3 inflammasome is the dominant driver of neutrophilic inflammation and disease progression in endotoxin-mediated ARDS” on October 23, 2026 at CSIR-Indian Institute of Integrative Medicine, Jammu. Ph.D work was completed under the supervision of Dr. Sheikh Tasduq Abdullah, and Co-Supervisor Dr. Sheikh Rayees Rafiq, AcSIR/CSIR-IIIM, Jammu @CSIR_IND @csiriiim
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Deepak Modi retweeted
Five years ago, an important miscarriage of justice occurred. The story began in April 2018 when David Sabatini, an MIT, Howard Hughes Medical Institute (HHMI), and Whitehead Institute scientist and professor began a consensual intimate relationship with Dr. Kristin Knouse, a principal investigator with her own lab at the Whitehead. By January 2020, David sought to end the relationship, but Knouse apparently did not want it to end. When David thereafter started a new relationship and Knouse learned about it, she began a secretive campaign to destroy him by attempting to end his career as a scientist. She did so by damaging his name, reputation, and that of his family with false sexual harassment and other claims, thereby making him unemployable. Knouse conspired with Dr. Ruth Lehmann, the then- and still current Director (i.e., President) of the Whitehead Institute, in her efforts to destroy Sabatini. The record presented in court demonstrated that Dr. Lehmann committed to Knouse in October of 2020 that she would fire David. Dr. Lehmann made this commitment to Knouse before any investigation of the facts had taken place. Seven months after committing to fire him, in March of 2021, Dr. Lehmann, on behalf of the Whitehead, hired the law firm of Hinckley, Allen, Snyder (HAS) to undergo an investigation of David. By July 2021, HAS shared a draft of its conclusions with MIT, HHMI, and the Whitehead, but not with David or his lawyers. On the morning of August 19, 2021, David for the first time received the more than 200-page investigative report and a calendar invite for a meeting the following day with Dr. Lehmann, the president of HHMI, and the HR directors of both institutions. The report was riddled with errors and unsupported claims about David and his relationship with Knouse. When David's lawyer immediately thereafter reached out to Whitehead counsel to ask whether David was about to be fired, they confirmed that he would be terminated at the meeting. On the advice of his lawyer, David immediately resigned from HHMI and the Whitehead rather than attend the meeting. HHMI did not accept his resignation, choosing instead to fire him. MIT put David on leave and ultimately revoked his tenure. David thereafter resigned from MIT. On August 20, 2021, one day after sending David the HAS report and before David had the opportunity to dispute the facts and the conclusions of the investigation, Dr. Lehmann emailed all employees at the Whitehead informing them that David had violated a number of Whitehead policies "including policies concerning sexual harassment." The Lehmann public email, David's resignation and firing, and Dr. Lehmann's claims about David's sexual harassment exploded into a major global scandal covered in mainstream, social, and scientific media around the world as it had all of the requisite ingredients: An attractive target with David, one of the most important scientists of his generation in line for the Nobel Prize, a purported inappropriate sexual relationship with a younger female colleague, and a political and institutional environment where punishing a man for sexual harassment advanced the career and reputation of the person and/or institution that destroyed the career and reputation of the accused, regardless of the validity of the allegations. As a result of Knouse's claims, Lehmann's sham investigation, and the media onslaught that followed, David lost all sources of income and his reputation was destroyed. All prizes he had been previously been awarded were withdrawn. He was removed from all scientific advisory and other honorary roles other than as a member of our family foundation's (the Pershing Square Foundation's) scientific advisory board. When I initially learned of the news about David in the summer of 2021, I hired him as a consultant to the Pershing Square Foundation as I believed our small foundation team would benefit greatly by his insights (and he now had the time to help us), and he needed the money to support his family. At my request and under a confidentiality agreement, David provided us with many hundreds of pages of documents including texts and other communications with Knouse, the investigative report, and David's responses to the allegations so that we could do our own evaluation of Knouse's claims. I and a member of our family office's legal team carefully reviewed the documents. After a careful review of the empirical documents -- in particular the texts between Knouse and David -- it became abundantly clear that Knouse's actions were that of an angry and jilted lover, not those of a sexually harassed junior colleague. And the investigative report appeared designed to deliver a pre-ordained conclusion rather than a dispassionate fact-based analysis. The impact of the firings and the destruction of his career and reputation on David and his family was extraordinarily devastating, so much so that we became increasingly concerned that he might commit suicide. [In order to make sure that David's important scientific research would continue, in February 2023, in partnership with an anonymous donor, we funded $25 million to support David launching a new lab. As you might expect, I was reviled in the press, in scientific journals, and on social media for doing so and for supporting a so-called sex offender.] On October 20, 2021, David filed suit against Knouse alleging defamation and tortious interference in his career and his contractual arrangements. Thereafter, Knouse brought counterclaims against David. Today, nearly five years to the date of the filing of the suit, he has finally received justice. Today, a 13-person jury (seven men and six women) of David Sabatini's peers (12 jurors plus an alternate) unanimously determined that David proved that Kristin Knouse defamed him, tortiously interfered with his contractual relationships (his entire career as a scientist), and tortiously interfered with his prospective advantageous relationships (his future employment). The jury awarded him nearly $10 million in damages including interest. The jury rejected all of Knouse's claims including her claims that David engaged in quid pro quo sexual harassment and created a sexually hostile work environment. While five years is a very long time to live under a reputational cloud, justice was finally served today for David, but not completely in my view. To this day, Dr. Ruth Lehmann remains Director of the Whitehead Institute. Dr. Lehmann worked alongside Dr. Knouse to destroy David Sabatini, an acclaimed scientist and professor. She did not follow due process before she intentionally destroyed David's career and reputation. Dr. Lehmann nearly killed David with her actions, as had we not rescued David by finding him employment, supporting him publicly to buffer the reputational damage, and supporting his recovery, he could have ended his life and left his son without a father before the world understood what had transpired here. And the reputational damage was not just to David. David's brother, Bernardo Sabatini, is one of the most important neuroscientists in the world. To this day, he has had to deal with a large cloud over his family name and reputation. Recently, when the new CEO of our brain institute mentioned that Bernardo Sabatini was on our board, he was asked: "Wasn't he involved in some kind of sex scandal?" For obvious reasons, the character of the person who runs a scientific institute is of utmost importance. Among other failures here, Dr. Ruth Lehmann committed to Knouse that she would fire David many months before an investigation was even launched and without consideration of the empirical facts. How can one trust research produced by a scientific institute if its leader is not committed to observing the empirical facts before reaching conclusions that have life-threatening import? We have unfortunately seen massive amounts of scientific fraud which has harmed innumerable human lives and wasted billions of dollars of research funding and time. For her ethical breaches here, Dr. Lehmann should be fired from the Whitehead. Based on her actions in this case, she is in no position to serve as the leader of an important scientific institute. I speak with some perspective on how scientific and other institutions should be led. Including the recent launch of the Ackman Oxman Institute, we have funded approximately $1 billion of scientific research and institutions over the last decade or so, and this experience has given us the opportunity to meet the leadership of many of the most important scientific institutions in the world. To put it plainly, we would not give a dollar to a scientific institute whose leader compromised basic moral principles as has happened here. At an absolute minimum, the board of the Whitehead should immediately launch a detailed and independent investigation of Dr. Lehmann's actions in the Sabatini case. I would encourage the investigation, among other considerations, to carefully exam all of the correspondence between Lehmann and Knouse, as well their correspondence with the HAS law firm on among other areas, the various drafts of the Sabatini investigative report. Alternatively, Dr. Lehmann could resign, minimize further distraction for the Whitehead, and save institutional time and resources that would be better spent on research that benefits humanity.
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When the lab vibes on festives Kudos to my team who balances science and social life Happy Dusshera/shubho bijoya to everyone from the DM LAB – at Uran, India
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– at Uran, India
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Deepak Modi retweeted
Dear President Kornbluth and Chairman Gorenberg, Yesterday, as I am sure you are aware, a Boston jury unanimously found that @MIT professor Kristin Knouse defamed David Sabatini, falsely accused him of rape and sexual harassment, and tortuously interfered with his contractual arrangements including his tenure at MIT. MIT and its tenure review committee relied on Professor Knouse’s statements when it took away David’s tenure and terminated him. MIT's policies explicitly prohibit harassment, retaliation, and fabrication of claims. Falsely accusing a colleague of rape and sexual harassment and pushing for his termination under false pretenses are clearly violations of MIT policy. In light of the unanimous findings of the jury after five years of discovery, many legal motions and countermotions by both parties, and a three-week trial in Suffolk County Superior Court in Boston: Is MIT going to take away Knouse’s tenure and terminate her? If not, why not? Is MIT going to restore David’s tenure, and apologize for firing him? If not, why not? In light of what has transpired in this grave miscarriage of justice, MIT has the opportunity and the obligation to right a serious wrong here. At a minimum, the public deserves transparency into what actions MIT is taking in this case as taxpayers are major funders of MIT. Sincerely, Bill Ackman
A civil jury ruled in favor of ex-MIT scientist David Sabatini, who was accused by a younger colleague of inappropriate sexual conduct in his Cambridge research lab, and awarded him $6 million in damages. trib.al/s3v9VIX
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Incredible that this 5 year nightmare is over. Institutions should admit that they made mistake because, as the jury concluded, they were lied to (defamation) and those lies were weaponized (interference) to get you fired. 3 wks testimony, 2 days deliberation, clear conclusion
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— NOT ALL HEROES WEAR CAPES Amidst this great news about Dr. David Sabatini’s huge court win against his defamer and MeToo hoaxer Kristin Knouse, there’s one person I want to take a moment to pay tribute to… Dafna Bar-Sagi. When @DMSabatini’s life was in ruins and he was a pariah in the academic world, this one woman fought the woke mob to try to get him a job at NYU. This happened after a convo with Sabatini where he bemoaned that he had been rendered professionally radioactive by the lies against him. Dafna tried to console her friend by saying that surely someone would hire him… But too often in life that “someone” always means “someone else.” Sabatini responded, “Well, would you hire me?” to prove his point that indeed no one would hire him. But do you wanna know what Dr Bar-Sagi did? She braved the woke mob and the scorn of her fellow academics and tried to hire him to her NYU department. And it almost worked. Unfortunately the woke mob won, at least for a while. But I for one will never forget her courage. Thank you Dafna. @BillAckman
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A civil jury ruled in favor of ex-MIT scientist David Sabatini, who was accused by a younger colleague of inappropriate sexual conduct in his Cambridge research lab, and awarded him $6 million in damages. trib.al/s3v9VIX
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Deepak Modi retweeted
Replying to @BostonGlobe
@ScienceMagazine , will you inform about this too if you were covering all defamation and helped to ruin a scientific carreer. Will you be brave enough to write about it now too, like you did in 2025 in this twisted story? science.org/content/article/…
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Congratulations to the newly minted dr and the proud mentor..
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Elated and humbled to be included amongst the top 2% scientist for 2026 Grateful to my students who have done all the hard work and my family who have brone my persistent absence. Thanks to all collaborators seniors and mentors, collegues and friends for all the support. – at Uran, India
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My student Nancy successfully defended her PhD yesterday and declared Ms Nancy to Dr Nancy Super proud of her achievements @icmrnirwoh
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Deepak Modi retweeted
Our PhD scholar, Ms. Nancy Ashary, will defend her doctoral thesis on "Understanding the Role of Endometrial HomeboxA10 in Regulation of Embryo Implantation". 📅 Oct 12, 2026 ⏰ 2:30 PM IST 📍 ICMR-NIRWoH, Mumbai / Online Scan QR code to join online!
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Open PhD Viva Voce of my student Ms Nancy Ashary. she will present her work on the discovery of a new mechanism of embryo implantation Do join on Monday 12 Oct 2026 using the QR code in the flyer @icmrnirwoh
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