Challenges in Drug Discovery: Biology— Paul Workman, Jason M. Sheltzer, Na Zhang, and Eric Spinetti addressed this topic in a session at the AACR Conference on Drug Discovery and Development. #AACRdrugdev26 @JSheltzer @EricSpinetti

Under hypothetical scenarios of a permanent 10% budget cut to the NIH and a nine-month drug review delay at the FDA due to staffing cuts, an estimated 53 drugs would not come to market over that time span. Now imagine if it was a 40% cut.

One week from today, the Nobel Prize in Medicine/Physiology will be announced. Here are the 79 most likely awardees, each of whom has won two or more pre-Nobel “predictor” prizes:

Mensageiro Sideral | Brasileira cria técnica para plantar tomate em Marte. Estudo de policultura pode ajudar a viabilizar futuras plantações em colônias espaciais www1.folha.uol.com.br/blogs/…

“I did multiomics” 1. Ran all the methods at my core facility in my samples 🎉 2. Some stuff correlates between the omes. Don’t ask about the stats 3. RNA and protein mostly don’t correlate but I won’t highlight that 4. Okokok I’ll just revert to cherry picking

Very proud of team Leukemia Drug Discovery for completing the @NucleateFL Activator program and bringing home 3 awards last night! @NucleateHQ Great job @EricSpinetti and Sana Chaudhry! @umiamimedicine @univmiami @SylvesterCancer

New salaries coming up: MS students - $27,000. PhD students - $40,000. Postdocs - $70,000. This is how the government can initiate a change in academia. ▫️ And yet there is one caveat. This budget is not ‘set in stone’. It’s $1.8 billion spread over 5 years first. It can be canceled after the federal election. ▫️ Many people ask why we get such small salaries in academia. A typical answer is: “It’s historical. It’s about passion, not money”. But in fact - it’s a political decision. If we follow the federal funding, we'll discover that its size inevitably comes from a political debate. Which basically brings us back to where we were: “In public opinion, scientists are passionate tinkerers who do not need that much money”. ▫️ Any opinion from the policy makers? #AcademicTwitter #phdlife @AcademicChatter

Analysis of a random selection of papers shared on social media showed no causative link between posting and citations go.nature.com/3TDj4VJ