@FlyFan7

pathologist

Joined June 2019
  • Tweets22.5K
  • Following2K
  • Followers849
29Media
fanbotao retweeted
Aysha Mubeen@AMubeen_Path21h
Pathology trainees: One image, no history. What do you think? #pathquiz #pathres
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Breast - Micropapillary carcinoma can show a distinctive HER2 IHC pattern - Basolateral or lateral, U-shaped membrane staining - Score as equivocal (2+) when staining is moderate to intense but incomplete (in >10% of tumor cells) → reflex to FISH - This pattern can be seen in some micropapillary cancers that are HER2 gene amplified (CAP Breast Biomarker Protocol, 2026). Dr. Allison. 2026 Diagnostic Pathology Update #USCAP #pathology #PathX
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🔬 When a T-cell lymphoma expresses CD20… think twice! An exceedingly rare case of CD20-positive primary cutaneous T-cell lymphoma, NOS, with an aggressive clinical course. The diagnostic challenge? True coexpression of CD3 and CD20—a finding that can easily raise the possibility of a B-cell lymphoma. T-cell receptor clonality and the overall clinicopathological picture were crucial in establishing the diagnosis. A striking reminder that aberrant immunophenotypes can challenge even our most familiar diagnostic algorithms. Read the full paper by Danielle R Rinck, Michael S Chang, Christopher Iriarte, and Robert Willim Link here bit.ly/4zWfZV7
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New in #HumPathol: BAP1 Loss and TFE3 Immunoexpression in High-Grade Clear Cell Renal Cell Carcinoma. sciencedirect.com/science/ar… #pathology #PathTwitter #PathX #GUpath
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A 70 Yr 👵 A Huge left ovarian mass. ➻ Thoughts ? #PathTwitter #FGT #Pathology #pathx – at Ethiopia
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Finally, a histologic biomarker for USP6-associated tumors, led by Margarita Muñoz de Toro @StanfordPath: pubmed.ncbi.nlm.nih.gov/4285… A new technique also highlighted in the excellent recent work by Dinh et al: pubmed.ncbi.nlm.nih.gov/4250… #BSTpath
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Tumors of the Breast, WHO 6th edition update: A high-grade or HER2-positive carcinoma with mucin should be called invasive ductal carcinoma/NST with mucin production/secretion Avoid “IDC with mucinous features.” Colleagues may interpret that as pure mucinous carcinoma, which this is not. Dr. Allison. 2026 Diagnostic Pathology Update #USCAP #pathology #pathX
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Parotid Oncocytomas Express the Glycoprotein Non-metastatic Melanoma Protein B (GPNMB): A Potential Link with Birt-Hogg-Dubé Syndrome A Peraza-Labrador, J Bishop, LS Schmidt, et al rdcu.be/FdAnLhUNSfLa #HeadNeckPathol #HNPJ #HeadandNeckPath #Pathology #ENTPath #PathologyTweet
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🎃 WTR Case Series | October 🔬 Case 11: Thyroblastoma, NOS • Primitive thyroid follicles • SALL4+ primitive cells • Immature neural elements • Focal mature bone & squamous nests 🧬 TTF1+ • PAX8+ • SALL4+ • Synaptophysin+ • TP53+ 👉 admin.worldtumorregistry.org… #Pathology
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fanbotao retweeted
Bin Xu@BinXu168 Jun 2017
Replying to @BinXu16 @kriyer68 @smlungpathguy @VijayPatho @sam_albadri @DraEosina @ENTpathology @marenwhymd @GeronimoJrLapac @Histopatolomon @Helena_Path @DrjohninNE @lara_pijuan @NRiddleMD @pathowitter
👍to all who get the diagnosis in no time. PTC Cribriform morular variant, with prominent supra & subnuclear vacuoles. #ENTpath #thyroid
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Happy to share that our study is now published in Human Pathology! We found that TFE3 expression is significantly more frequent in BAP1-deficient clear cell RCCs, potentially creating a diagnostic pitfall, particularly in limited biopsy specimens. sciencedirect.com/science/ar…
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Kidney can also have lots of different tumors. Female, 45yo with a metanephric adenoma!. Stains are PAX8 and WT1
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Epithelioid mesothelioma in the peritoneum: • Can look morphologically similar to serous borderline tumor (pic 1) • Can show calcifications similar to low-grade serous carcinoma (pic 2) Warning: PAX8 and SOX17 are not reliable in this differential, they can be positive in up to ~15% of peritoneal mesotheliomas Helpful stains: ER and PR are almost always negative in mesotheliomas An ER/PR-positive proliferation is unlikely to be a mesothelioma Dr. Chapel. Peritoneal Mesothelial Pathology #ISGyP #pathology #PathX
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🔬 Folliculin mutated renal tumor: H&E & GPNMB IHC Want to sharpen your GU pathology expertise? Join Johns Hopkins faculty for Contemporary Issues in GU Pathology: What Every Pathologist Should Know, Feb 5–7, 2027. Online CME/MOC with updates on WHO classifications.
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Today's case. Not too hard, but fun. Appendix mass. #pathology #gipath
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Histopathological patterns for the specific diagnosis of lymphadenopathies (LADs), illustrating architectural alterations in lymph node compartments. 🔬 mdpi.com/2673-6357/5/3/26
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Bone. What is your diagnosis?🔎 Poll below 🗳️👇 #PathPuzzle 🕵️‍♂️ @UMichPath #Pathology #PathX #PathTwitter
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One look at this intraoperative smear prep and you can diagnose this brain tumor. #pathology #neuropath #pathtwitter
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Direct tumour–adipocyte contact/Stroma AReactive Invasion Front Area (TAC/SARIFA) predicts adverse outcome in colorectal cancer: a focused evidence synthesis and meta‐analysis #GIpath pmc.ncbi.nlm.nih.gov/article…
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Read the article "Periocular Endocrine Mucin-Producing Sweat Gland Carcinoma and Mucinous Carcinoma—An Institutional Series Including 49 Patients" by Dr. Stone et al. Link to read: mdpi.com/2296-3529/13/4/48
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