Former @wakefb LB. Author. Hormone educator. Peptides. Testosterone. Recovery. Performance. Join 200k+ on my email list 👇
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Hunter Williams retweeted
People think Reta is just a fat loss drug.
At a low dose it partitions nutrients. Stack it with testosterone and a GH peptide and you can build muscle on it.
Hunter Williams retweeted
Also available on 👇
YouTube: youtube.com/watch?v=CyVMRGfB…
Spotify: open.spotify.com/episode/5lb…
Apple: podcasts.apple.com/us/podcas…
Hunter Williams retweeted
Hunter Williams points to a study where non-exercisers' muscle ended up looking younger than the muscle of people who actually worked out.
The peptide was SLU-PP-332.
Researchers took muscle tissue from women who'd had hip surgery, women who didn't exercise, and treated it in a dish.
The treated tissue started behaving as if it had been trained.
Then they compared it to tissue from women who did exercise.
The treated, sedentary tissue came out looking younger and better than the tissue from the women who'd actually been working out.
Williams, who's tested it on himself, calls it another version of exercise in a pill.
This was human tissue in a culture, not a full human trial, so hold it loosely.
But it's the kind of result that stops you cold.
— Hunter Williams (.@HunterEsoteric) on Ayik Kafa's LongeviLab podcast (.@longevilab)
People with Alzheimer's almost always show very low levels of one protective peptide, says Hunter Williams.
It's called humanin, and Williams, who's studied the mitochondrial peptides closely, calls it the "brain's guard dog".
Its job is to protect the mitochondria, especially in the brain, and to block the buildup of tau proteins, the tangles tied to Alzheimer's.
The striking part is what shows up when you look at sick brains.
"Almost always we can look at people that have Alzheimer's or dementia and they have very very low levels of humanin."
Whether raising it back protects them is still being worked out, so hold the hope carefully.
But the peptide that guards the brain running dry in exactly the people losing theirs is hard to look away from.
— Hunter Williams (.@HunterEsoteric) on Ayik Kafa's LongeviLab podcast (.@longevilab)
Hunter Williams retweeted
Dr. Bakri says every peptide on the US market is made from raw materials in China.
It doesn't matter where you bought yours - the origin is the same.
• Active ingredients all from China
• Pharmacy and gray market alike
• US-made peptides barely exist
The active ingredient for these drugs comes from China.
Bakri says there is no such thing as an American-made peptide. The raw material ships over, then gets finished and packaged here.
"Everything's Chinese peptides. There's no Guatemalan peptides."
That covers the semaglutide in your compounded vial and the BPC-157 off a research website. One country makes both, then the labels change. A few groups want to make them here, but it would cost a fortune.
Whatever the label on your vial says, it started in the same place.
— Dr. Abud Bakri (.@AbudBakri) on the Huberman Lab podcast (.@hubermanlab)
Dr. Bakri says women told they were infertile are getting pregnant by accident on GLP-1 drugs.
Doctors now call them ozempic babies.
Here's why it happens.
Your fertility is gated by a fat hormone called leptin, your body's "fuel gauge".
When you carry too much body fat, you become leptin resistant and the gauge jams.
Your body reads it as the wrong time to reproduce.
GLP-1 drugs strip the fat off.
Leptin starts working again, so the body gets the all-clear and switches reproduction back on.
He says these were overweight women who weren't even trying.
"A lady will be subfertile or infertile, start a weight loss drug, and then find out by accident she's pregnant."
— Dr. Abud Bakri (.@AbudBakri) on the Huberman Lab podcast (.@hubermanlab)
Hunter Williams retweeted
Hunter Williams says there's a peptide that tricks your body into thinking it just exercised.
Williams has tracked thousands of people using peptides, and the one he points to here is MOTS-c, a molecule your own body already makes inside its mitochondria.
As you age, your levels fall.
Supplement it back, he says, and it sends a signal that mimics a workout.
"It creates a signaling cascade that tells the body that it's in a state of exercise."
That means the same chemical response as a training session, better energy, higher metabolism, improved insulin sensitivity, without the session itself.
It works better stacked with real exercise, and this is his experience and early research, not settled medicine.
But even alone, he says the body responds as though you'd trained.
The workout, it turns out, may be a signal you can send without moving.
— Hunter Williams (.@HunterEsoteric) on Ayik Kafa's LongeviLab podcast (.@longevilab)
People with Alzheimer's almost always show very low levels of one protective peptide, says Hunter Williams.
It's called humanin, and Williams, who's studied the mitochondrial peptides closely, calls it the "brain's guard dog".
Its job is to protect the mitochondria, especially in the brain, and to block the buildup of tau proteins, the tangles tied to Alzheimer's.
The striking part is what shows up when you look at sick brains.
"Almost always we can look at people that have Alzheimer's or dementia and they have very very low levels of humanin."
Whether raising it back protects them is still being worked out, so hold the hope carefully.
But the peptide that guards the brain running dry in exactly the people losing theirs is hard to look away from.
— Hunter Williams (.@HunterEsoteric) on Ayik Kafa's LongeviLab podcast (.@longevilab)
Hunter Williams retweeted
Reader Mailbag 4 is up. We covered too much and the file was too big for X so head to YouTube.
Anhedonia on GLPs, Reta and heart rate, hormones for women in their 20s and 30s, accidental peptide overdoses, and teen acne.👇
youtube.com/watch?v=5mUeLJNh…
Hunter Williams retweeted
Please
Please
Please
Please
Please
Get your bloodwork done
At least once a year, ideally quarterly
ESPECIALLY if you are going to start DIYing your own PED/Peptide protocol
Hunter Williams retweeted
I answered every peptide question my audience sent in this month.
02:42 Can you use GLPs while trying to get pregnant?
04:48 My hunger increased on Reta but I am not losing weight, why?
05:26 Does Reta, Tirz, or Sema affect dopamine the most?
12:02 I switched from Tirz to Reta and now I have bad anger and anxiety, why?
13:26 Why do GLPs stop working when you cycle off and come back on?
16:06 GLPs are causing anhedonia, what can I use for fat loss instead?
18:44 Do women lose more on Tirz than Reta?
19:06 Do GLPs affect libido and sex drive?
19:24 My SHBG is 55 and my free T is low, how do I lower SHBG?
24:34 My doctor wants to start me at 60mg of testosterone, my friend says 200, who is right?
30:20 What is your go-to injury healing stack?
33:06 What is the peptide protocol for lupus and rheumatoid arthritis?
33:58 What stack helps with studying and cognitive performance?
39:08 Are there peptides that help with tinnitus?
41:10 What are your thoughts on rapamycin?
45:46 Should teenagers use peptides?
46:00 What peptides help with prostate issues?
Hunter Williams retweeted
This cheat sheet you put together is FANTASTIC Hunter. Thank you for giving it out. Currently healing a knee injury thanks to you. 👊🏻
Hunter Williams retweeted
Everyone says peptides cause cancer.
I pulled the studies. Here's what they actually show.
06:25 BPC-157
08:40 DSIP
09:54 Epitalon
12:15 GHK-Cu
14:45 KPV
16:03 LL-37
18:41 MOTS-c
20:00 Retatrutide
21:19 Semaglutide
22:24 SS-31
24:13 Thymosin Alpha-1
25:47 Tirzepatide
Watch more → youtube.com/@TheHunterWillia…
Hunter Williams retweeted
Peptides for #immunity help maintain homeostasis by modulating the immune response.
They make your body more EFFECTIVE & EFFICIENT at what it already does.
Reply to this tweet with “CHEATSHEET” and I’ll DM you my peptide cheat sheet detailing the BEST way to dose these immune-boosting peptides. 🎁📩
Hunter Williams retweeted
They deleted my YouTube a few months ago.
300 hours of peptide and health content just gone.
Except it wasn't. I had already built a backup library and every video is still there completely free.
If you've been looking for something I used to cover it's probably in here 👇
library.hunterwilliamshealth…
Hunter Williams retweeted
Millions of people have this condition.
Their doctors call it "autoimmune disease."
It's actually mold toxicity.
Here's how to reverse it in 12 months:
Hunter Williams retweeted
This study is real and the mechanism makes complete sense. Most people don't realize that traditional oatmeal is essentially a sugar delivery system with a health halo.
That said not all oats are created equal. The problem isn't oats themselves it's the sugar, the processing, and the glycemic load. We built ZEROats specifically because of this exact issue. No added sugar, high protein, designed to not spike your blood sugar the way traditional oatmeal does.
You can have your oats and your stable insulin too. zeroats.com
Is oatmeal really a healthy breakfast?
Dr. Mark Hyman blew this up with a fascinating Harvard study.
They gave overweight teens the exact same calories for breakfast: oatmeal, steel-cut oats, or an omelet. Then let them eat freely the rest of the day.
The oatmeal group ate 81% more food than the omelet group. They also had much higher insulin, cortisol, and adrenaline — their bodies were basically in stress mode. Even the steel-cut oats group ate 50% more than the omelet group.
High-carb breakfasts spike blood sugar and insulin, which drives hunger hormones (ghrelin) and crashes energy later. Protein + fat stabilizes blood sugar and keeps you full longer.
This one really made me rethink my old habits. I used to default to oatmeal thinking it was the “healthy” choice. Turns out I was working against my body.
What you eat first thing dramatically affects your hunger, energy, and cravings for the rest of the day.
What’s your go-to breakfast these days — and has changing it made a difference in how you feel?
Hunter Williams retweeted
Longevity researchers just found microplastics in human brain tissue.
Concentrations higher than in the liver or kidneys.
And it increased 50% in just 8 years.
Dementia patients had 10x more than everyone else.
Let that sink in.
→ Microplastics cross the blood brain barrier
→ They accumulate faster than the body can clear them
→ They correlate with neurodegeneration
→ They're in the water you drink
→ They're in the air you breathe
5 things you can start doing today:
→ Switch to a quality water filter — reverse osmosis removes up to 99% of microplastics
→ Sauna 3-4x per week — sweat is one of the most effective excretion pathways
→ Add a binder — zeolite, activated charcoal, or chlorella bind and remove toxins
→ Ditch plastic food containers — heat accelerates leaching into your food
→ Weekly glutathione — supports liver detox pathways and cellular repair
You can't avoid exposure entirely right now.
But you can tip the scales in your favor.
Hunter Williams retweeted
1 in 2 men over 50 wake up multiple times to urinate.
Destroying deep sleep & tripling the risk of metabolic dysfunction.
That's why I put together this thread on fixing prostate health (without jumping straight to surgery): 🧵
Hunter Williams retweeted
After THOUSANDS of peptide experiments, we
discovered why 90% of users get mediocre results.
It's not the peptides.
It's the protocols.
We've developed a system that makes peptides work flawlessly.
Here’s how we did it (why this changes everything): 🧵
Hunter Williams retweeted
Statins: The $30 billion band-aid
Muscle pain. Fatigue. Diabetes risk.
All to "manage" cholesterol that returns the moment you stop.
One compound reduces heart-related deaths by 38%
not by lowering numbers, but by repairing endothelial
dysfunction.
The cardiovascular solution hiding in plain sight:🧵
