Chemist interested in MDR-protein transporters. BScChem @UNAM_MX. Research Fellow @PasteurLille @institutpasteur. Enjoy Deep and Wreck Scuba Diving
France
Joined July 2016
- Tweets311
- Following98
- Followers77
- Likes622
Juan Carlos retweeted
Demis Hassabis and John Jumper, the 2024 Nobel Prize laureates in chemistry, have developed an AI model to solve a 50-year-old problem: predicting proteins’ complex structures.
In 2020, Hassabis and Jumper presented an AI model called AlphaFold2. With its help, they have been able to predict the structure of virtually all the 200 million proteins that researchers have identified. Since their breakthrough, AlphaFold2 has been used by more than two million people from 190 countries. Among a myriad of scientific applications, researchers can now better understand antibiotic resistance and create images of enzymes that can decompose plastic.
The illustration below explains how it works.
Read more about their story: bit.ly/4diKiJ2
Juan Carlos retweeted
"I'm in a cheap hotel in California which doesn't have a good internet or phone connection. I was going to have an MRI scan today but I'll have to cancel that!"
- New physics laureate Geoffrey Hinton speaking at today’s press conference where his #NobelPrize was announced.
ALT Illustration of Nobel Prize laureate Geoffrey Hinton.
Juan Carlos retweeted
Sad news - a pioneer in antimicrobial resistance, highly respected colleague and good friend passed away
dignitymemorial.com/obituari…
Juan Carlos retweeted
Rapid evolution of colistin resistance in a bioreactor model of infection of Klebsiella pneumoniae | Communications Biology nature.com/articles/s42003-0…
Juan Carlos retweeted
A combined microbiological and mathematical approach to study colistin resistance in antibiotic sensitive K. pneumoniae reveals a rapid emergence and selection of genetic variants generated by spontaneous mutations in key regulatory genes.
@ThamaraiSch
doi.org/10.1038/s42003-024-0…
An amazing work has been crystallised by @ThamaraiSch , Bartlomiej Waclaw et al in @CommsBio @NaturePortfolio. We show the rapid evolution of colistin resistance and the importance against using colistin as a monotherapy for K. pneumoniae infections. nature.com/articles/s42003-0…
Juan Carlos retweeted
Happy to share our new computational methodology to predict binding of ligands on very challenging proteins, just published on @biorxiv_biophys. Great collaboration between @univca, @DeptChemUU, and @TempleUniv!!! 👇👇👇💪💪💪
Juan Carlos retweeted
Physicist Peter Higgs has passed away at the age of 94. The Higgs particle, often called the God particle, is named after him.
Higgs was awarded the 2013 physics prize for the theory of how particles acquire mass.
Watch our interview with him: youtu.be/0WduRCAlIig
ALT Official Nobel Prize portrait of Peter Higgs. He is wearing a dark suit and white shirt and a dark blue tie.
Juan Carlos retweeted
Really excited to share my first preprint about the role of FakA in biocide tolerance 🏥🧫🔬🧬🖥️
@bluebirdsjunk @harshasiani @Cwhitch @ma_webber @TheQuadram @GamaHealthcare
▶️ biorxiv.org/content/10.1101/…
FakA impacts antiseptic susceptibility in Staphylococcus aureus and Enterococcus faecalis biorxiv.org/cgi/content/shor… #biorxiv_micrbio
Brilliant work by all the members of #EFFORT Consortium!! Very much looking forward to seeing these new EPIs scaffolds reaching final in vivo testing stages!!!
Yes! Our allosteric efflux pump inhibitor boosts antibiotic efficacy against Klebsiella pneumoniae. doi.org/10.1038/s44321-023-0…. Collab with Ruben Hartkoorn (@Hartkoorn_Lab), Marion Flipo (both Pasteur Institute in Lille), and Achilleas Frangakis (@Achilleas49er), Goethe University.
Juan Carlos retweeted
First time I get the cover of a magazine and it's in @Nature! Had this idea to illustrate the diversity captured by the MX Biobank across Mexico and brilliant designer @mauguz33 brought it to life inspired by indigenous Huichol art from near my home town. nature.com/nature/volumes/62…
The Myth of Ethidium Bromide | Science | AAAS science.org/content/blog-pos…
2
64
Juan Carlos retweeted
Take a look at Johannes Diderik van der Waals 1873 doctoral thesis where he first derived his equation of state: (P+a/V2)(V-b) = RT. This was the foundation for his future work on the state of gases and liquids. Van der Waals was awarded the Nobel Prize in Physics 1910.
ALT Front page of Van der Waals' thesis
ALT Page of Van der Waals' thesis
Juan Carlos retweeted
The future is here!
Building molecules in #VirtualReality with my hands, by combining @threejs, Cannon.js, @adrian_roitberg 's ANI and more. 😎 And in the web!
Here running in the browser of a @MetaQuestVR headset.
Thanks @fabiojcortes and @LucienKrapp
Juan Carlos retweeted
This week in Nature: Mexican genomics – biobanks offer genetic insights into the diverse population of Mexico. Browse the full issue here: nature.com/nature/volumes/62…
Juan Carlos retweeted
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
Juan Carlos retweeted
AlphaFold inventors Demis Hassabis and John Jumper have won a Lasker award. The annual prize rewards achievements in biomedical research and is often considered a precursor to the Nobel prize. Discover how their breakthrough AI tool is changing biology go.nature.com/3ENaqNh
Juan Carlos retweeted
Google DeepMind says it’s trained an artificial intelligence that can predict which DNA variations in our genomes are likely to cause disease—predictions that could speed diagnosis of rare disorders and possibly yield clues for drug development. trib.al/5bwR9v1
Accurate proteome-wide missense variant effect prediction with AlphaMissense | Science science.org/doi/10.1126/scie…
1
64