Hematologist/oncologist, Staff Physician @ClevelandClinic, plasma cell & genomics enthusiast, ex-VC analyst, dad, views my own, #myeloma, #amyloidosis, #NSNO
Joined July 2020
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Louis Williams retweeted
🎉 Out now! In the latest episode of The HemOnc Pulse with @LouisWilliamsMD and @RahulBanerjeeMD, discover how AI is reshaping hematologic oncology research, helping investigators analyze data, improve trial oversight, and accelerate clinical development.
▶️ buff.ly/SFWD7ms
De-skilling and non-skilling with the proliferation of AI in medicine are legitimate concerns. I would argue that there is at least as much potential for skill enhancement and innovation. This effort is a nice step in that direction. The platform will only improve in the future.
Louis Williams retweeted
New in @NEJM_AI: @LouisWilliamsMD and Dr. Zeshaun Khawaja (@BustaClot) of @ClevelandClinic and our Chief Medical Officer @TimShowalter1 lay out five pillars for scaling clinical AI across a health system.
ai.nejm.org/doi/full/10.1056…
#ClinicalAI #HealthcareAI
Really enjoyed the chance to sit down and have a thoughtful conversation with @RahulBanerjeeMD and @Blood_Cancers. Thank you very much for the invitation. There is so much for us all to learn in this space. @ClevelandClinic @jamecancerdoc
🎙️ In this episode of The HemOnc Pulse, explore how AI is advancing hematologic cancer care through machine learning, genomic data, early detection, clinical decision-making, and patient monitoring with @LouisWilliamsMD and @RahulBanerjeeMD.
➡️ buff.ly/3TnOnG7
Louis Williams retweeted
Episode 2 just dropped! How do you envision #AI fitting into #clinicaltrials? Hear what experts @RahulBanerjeeMD and @LouisWilliamsMD have to say! 👉👉 podcasts.apple.com/us/podcas…
Louis Williams retweeted
Join us for the upcoming IACH Multiple Myeloma Masterclass Series:
𝗖𝗔𝗥-𝗧: 𝗢𝗽𝘁𝗶𝗺𝗶𝘇𝗶𝗻𝗴 𝗕𝗿𝗶𝗱𝗴𝗶𝗻𝗴 𝗧𝗵𝗲𝗿𝗮𝗽𝘆 𝗮𝗻𝗱 𝗘𝗮𝗿𝗹𝘆 𝗥𝗲𝘀𝗽𝗼𝗻𝘀𝗲
with Rahul Banerjee
Tuesday, November 3
6 pm CET • 12 pm NY
Register now for free👇
us06web.zoom.us/webinar/regi…
@RahulBanerjeeMD @Mohty_EBMT
Really enjoyed sitting down with @RahulBanerjeeMD and @Blood_Cancers to discuss our approach to #AI across the @ClevelandClinic cancer service line and the tremendous potential for emerging models across #hematology more broadly. @jamecancerdoc @CleClinicMD #mmsm
bloodcancerstoday.com/podcas…
Our framework and some ideas along with Zeshuan Khawaja and @TimShowalter1 for scaling #AI models across the @CleClinicMD cancer service line and a case study in the form of our ongoing collaboration with @viz_ai (sponsors of the perspective article for transparency). @jamecancerdoc @FaizAnwerMD1
ai.nejm.org/doi/full/10.1056…
Louis Williams retweeted
One of the clearest signals from last week's AI Vizionaries Summit: clinicians don't want to go back to their pre-AI ways of working.
The conversation wasn't about whether clinicians will adopt AI. It was about what adoption actually looks like once AI is already part of the workflow. @Viz_ai and @HLTHEVENT invited clinicians, health system leaders, and pharma executives to sit together in the same room to work through exactly that, from identifying the right patients earlier to supporting the calls clinicians make every day.
What the clinicians said:
- The best AI works as a safety net
- AI earns its place in the workflow
- Scale is what turns a good tool into better care
What pharma said:
- AI has moved from the back office to the point of care
- The hard part is implementation
- Workflow AI belongs in core pharma plans
Trust, workflow integration, clinical value, alignment across stakeholders: that's what kept coming up, and none of it comes from the technology alone.
Thank you to @HLTHEVENT, our panelists from @SanofiUS , @Novartis, @Merck, @CooperHealthNJ, @ClevelandClinic, @JeffersonUniv, and Integrated Medical Professionals.
Stay tuned for the full report from our Summit, and meet us at #HLTH2026 in Las Vegas, November 15-18.
#HealthcareAI #LifeSciences #ClinicalAI #MedicalAffairs #HLTH
Louis Williams retweeted
Finally!! 🙌🙌🙌
I am honored to serve again as the Editor for #Multiple #Myeloma, A Textbook for Nurses, 4thEd.
Please feel free to share this link 👇 communities.ons.org/particip… with your colleagues and let me know if you have any ❓. The signup deadline is 10/11/26. Prior 3ed. authorship is not a guarantee for this edition. Help us update and advance #nursing knowledge!
Louis Williams retweeted
In a phase 1 study of anito-cel, a CAR T-cell therapy, for relapsed or refractory myeloma, all 38 patients had a response. Severe cytokine release syndrome and immune effector cell–associated neurotoxicity syndrome were rare. Full study results: nej.md/4ArvK6r
Science behind the Study: Anito-cel for Multiple Myeloma nej.md/4hF5Gxj
ALT A graph from an Original Article published in the New England Journal of Medicine article titled "Phase 1 Study of Anito-cel, a D-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma." The graph shows progression-free survival among all patients who received anito-cel. The NEJM identity sits at the bottom.
Louis Williams retweeted
Fascinating conversations with Dr. Kyle in 2019 for @ASCOPost ascopost.com/issues/april-25… Truly remarkable journey of a giant in modern medicine @MayoClinic @VincentRK @myelomaMD
Louis Williams retweeted
Our recent review in @AjHematology covers the latest updates in Plasma Cell Leukemia, including epidemiology, biology, outcomes with contemporary therapies, emerging encouraging data with immune effector therapies and a roadmap for the future!
Many ongoing studies exploring the earlier utilisation of immune effector therapies in the highly aggressive subset.
Led by @MahinBhatt
@VincentRK @myelomaMD @Myeloma_mSMART @MayoCancerCare
onlinelibrary.wiley.com/doi/…
Louis Williams retweeted
I agree with the diagnosis in the article, but there’s a paradox it misses: academic medicine helps create the very problem it laments
Yes, we underpay people relative to their value, then moralize about it. Leave for pharma? “The dark side.” Consult for industry? COI. Move to start up? Too aligned with payers. Negotiate aggressively? Not mission-driven enough or even worse have to answer to non-physician administrators
Law, business, tech and politics accept that talented people seek compensation, influence, ownership, and value
Maybe the problem is that we’ve built a culture where wanting to be fairly rewarded is treated as a character flaw or selfish
Louis Williams retweeted
We had more than 1000 care givers attended our Second AI in Healthcare Conference @ClevelandClinic @CleClinicNews from 33 different states and 7 different countries! Making it one of the largest Caregiver focused patient centered AI Conference in the World !! @CIOCHIME @ScottRSteeleMD
Today we brought together health care professionals from around the country to focus on the growing role of AI in healthcare.
Learn more: cle.clinic/3UGitGQ
Louis Williams retweeted
@ClevelandClinic has been a Viz.ai partner since our early work in stroke care coordination. Since then, the partnership has expanded into cardiology, deeper EHR integration, and new work in oncology and pulmonary care.
Today at Cleveland Clinic’s AI Summit, Viz.ai’s Dr. @TimShowalter1 joined Cleveland Clinic leaders Dr. Zeshaun Khawaja @BustaClot and Dr. @LouisWilliamsMD for a panel on AI at Scale: How Health Systems Are Turning Promise into Practice.
The panel discussed what it takes to move beyond individual AI deployments towards an enterprise approach:
→ Start with the clinical problem
→ Bring clinical, IT, data and operational leaders together early
→ Build governance, infrastructure and integration that reduce friction as AI expands
→ Integrate into clinical workflows
→ Measure success by the impact on patient care, operations and the clinician experience
Cleveland Clinic is building on what works and extending the value of clinical AI to more clinicians, specialties and patients. It’s a model for how sustained partnership can help health systems move from individual use cases toward an enterprise approach.
Thank you to Cleveland Clinic for bringing healthcare leaders together and to Dr. Khawaja and Dr. Williams for sharing their experience.
#HealthcareAI #ClinicalAI #AIatScale #DigitalHealth
Stepping into a technology facing role as a clinician is challenging. I discussed issues related to #AI implementation with @BustaClot,
@TimShowalter1 and @viz_ai at the @ClevelandClinic Healthcare AI summit. Here are my thoughts on three quick questions to ask yourself about the scaling of #AI if you’re a clinician responsible for digital strategy at an academic cancer center.
2. What could this “look like” in a cancer center?
For marginal cost to come down, a good start might include the following: a smooth governance structure tiered to risk level of individual models, a portfolio-based strategy, fully developed data infrastructure and stack that (EDW, data lake, etc) to reduce friction in model deployment, and a seamless workflow for implementation and for broader operational deployment of successful pilots.
Great resources available, especially on governance from @CHAI_nonprofit
chai.org/workgroup/responsib…
3. How do you work with technology experts to get there?
Mutual understanding should prevail. Clinicians in these roles should invest in learning how common models work. You don’t need a degree in computer science but you do need to know the lexicon and general concepts. Technology experts and data scientists should be included early on when addressing a clinical problems. Finally, responsibility for long term quality assurance should be shared.
Lots of great resources out there.
Highly recommend asking your favorite #LLM how it works. Then prompt it to describe typical layers of data architecture in a typical cancer center.