Associate Dean for Undergraduate Education @IUBloomington @IUluddy • multicellular systems & cancer with @PhysiCell • #OpenSource • astrophotography

Bloomington, IN USA
Joined July 2011
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Replying to @astrocatinfo
Thanks! Alas not a dual--just the one Tak. – at Ralston, NE
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Replying to @astrocatinfo
Looks really nice, Aleix! I'm setting up my Tak-Epsilon 180ed right now, and hope to give it a shot on a comet. f/2.8 hopefully will work for getting some tail details! Any advice?
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That was fast! Amazed you got in to even see that result! I was at error 429 even at 10:59 am
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Yep, this is pretty much how I figured the 11 am caviar promo would turn out at @McDonalds
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Replying to @Magnetodawn
Happy 2026 to you! Please LMK if you do find yourself on BlueSky. (I'm there under same username.)
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Paul Macklin retweeted
Waited in a 90-minute line in the rain to get one last Sprinkles Cupcake before all of the stores shut down forever. Corporate America delivering one last shitty moment to ring out a very shitty year. Fuck 2025 and fuck private equity.
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Paul Macklin retweeted
Thrilled to see our project on the cover of this week's @ScienceMagazine. Incredibly fun and rewarding collab with the public, @eliz_aguilar2 @JuncoWren @imillercrews @MathCancer
As the Moon eclipsed the Sun on 8 April 2024, birds took note. Leveraging nature’s own experiment, scientists and the public joined forces to show how different species responded to sudden midafternoon darkness followed by a new “dawn.” Learn more this week in Science: scim.ag/46J1bN5
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Epic indeed, @JoshuaABull !
What's it like round here? What are the people like? What do they do when they are not doing maths? Do they have fun? Films about people who also do maths. @JoshuaABull
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Paul Macklin retweeted
This week in Math Onco 345: Darwinian evolution, digital twins, multiscale modeling, and antifragility Art: @MathCancer & Heber L Rocha 😎💯
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In a serious case of a weirdly small world, I ran into @Seirin_Lab at @OxUniMaths in the visitor office. What a joy!
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Replying to @FabianSpill
Thanks, Fabian! and was great to see you at SMB!!!
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And we're just getting started! We are now working to make it easier to load, export, share, and recombine models written in the grammar, and next-generation extensions of the language. Also working with other open source leaders to support the grammar for model exchange
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Thank you! Yes, the grammar is already fully incorporated in @PhysiCell, and you can try it yourself with web-based PhysiCell Studio. Please do!! I suggest a recent short course we taught last week that gives a taste! :-) github.com/physicell-trainin…
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And we're beyond grateful for early support by the @JKTGFoundation (and even earlier by @BCRFcure) and @theNCI and @NIH. Without early support for basic sciences, we would never have been in the position to create this work today! 17/17
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It was a great honor to work with this team. We have accomplished something beautiful together we could never have done on our own. It is an honor to count them as colleagues and friends! 16/n
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You may notice that these examples are 2D. We used 2D to rapidly iterate development of each of these models, but the grammar is tied to cell behaviors, not 2D or 3D. We were able to rapidly convert a 2D tumor-immune model to 3D, with ZERO changes to the model rules! 14/n
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And in work led by Genevieve Stein-O'Brien (@GenesOfEve) and her team, she showed that the grammar isn't just limited to cancer or even cancer immunology. They built a model with @AllenCellInst brain atlas data, and modeled neurocortex development! 13/n
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In their work, they were able to show how combining simple rules that "encode" single immunotherapies (again, no hand-written code!) could simulate and predict combination therapies, with big differences in ranked efficacy based on initial immune profiles! 12/n
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