Organisation for the Prevention of Intense Suffering is a think-and-do tank promoting ethical governance based on compassion for all sentient beings

Switzerland
Joined March 2017
Our new paper "The Moral Blind Spot in AI Governance: Risks of Large-Scale Suffering". Technically aligning powerful AI systems with flawed societal values risks preserving our moral blind spots and locking them in as durable features of the future papers.ssrn.com/sol3/papers.…
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Jonathan Leighton of Organization for the Prevention of Intense Suffering (OPIS): 𝗥𝗲𝘀𝘂𝗹𝘁𝘀 𝗳𝗿𝗼𝗺 𝗢𝗣𝗜𝗦'𝘀 𝘀𝘂𝗳𝗳𝗲𝗿𝗶𝗻𝗴 𝘀𝘂𝗿𝘃𝗲𝘆 > Last autumn and winter, we carried out a survey to evaluate the suffering people experience from a range of conditions and experiences, collecting 485 responses. The goal was to gather data on suffering intensity and duration, which can be used to influence policy-setting and prioritisation, and ensure that those experiencing the most severe suffering are not neglected. Current metrics used in healthcare economics don't directly measure suffering, and I have argued for the use of specific metrics that focus on severe and extreme suffering. I've just published a post in the EA Forum with an analysis of our survey results. This analysis will help in designing a much larger round that can generate reliable data for a wide range of conditions. Link in the first comment.
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We are pleased to announce our new, wide-ranging publication "Compassionate Governance: A Strategic Guide to Preventing and Alleviating Global Suffering" available for free download or paperback order. Launch webinar on 25 June. preventsuffering.org/compass…
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Our new case series on 9 cluster headache patients treated with psychedelics + ketamine under compassionate use provisions at the Zurich pain clinic of Livia Granata, adding to the evidence pool and supporting an expanded role for such treatments @OPISOrg doi.org/10.1177/251581632513…
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𝗪𝗲'𝗿𝗲 𝗱𝗲𝗹𝗶𝗴𝗵𝘁𝗲𝗱 𝘁𝗼 𝗮𝗻𝗻𝗼𝘂𝗻𝗰𝗲 @JonLeighton1 𝗮𝘀 𝗮 𝘀𝗽𝗲𝗮𝗸𝗲𝗿 𝗮𝘁 𝗔𝗜, 𝗔𝗻𝗶𝗺𝗮𝗹𝘀, & 𝗗𝗶𝗴𝗶𝘁𝗮𝗹 𝗠𝗶𝗻𝗱𝘀 𝗟𝗼𝗻𝗱𝗼𝗻 𝟮𝟬𝟮𝟱! 🌍 Jonathan is the Executive Director of the Organisation for the Prevention of Intense Suffering @OPISOrg , a Swiss think-and-do tank he founded to prioritize preventing suffering across all sentient beings. His talk at #AIADM25 "Embedding Compassionate Ethics into AI and Governance" will address the urgent challenges of incorporating ethical frameworks into AI systems and governance structures, drawing from his recent book "The Tango of Ethics" and OPIS's upcoming Guide to Compassionate Governance. 🎟️ 𝗝𝗼𝗶𝗻 𝗮 𝗰𝗼𝗺𝗺𝘂𝗻𝗶𝘁𝘆 𝗼𝗳 𝟭𝟬𝟬+ 𝘁𝗵𝗼𝘂𝗴𝗵𝘁 𝗹𝗲𝗮𝗱𝗲𝗿𝘀 𝗮𝗻𝗱 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗼𝗿𝘀! 𝗙𝗶𝗻𝗮𝗹 𝗿𝗲𝗴𝗶𝘀𝘁𝗿𝗮𝘁𝗶𝗼𝗻 𝗰𝗹𝗼𝘀𝗶𝗻𝗴 𝘀𝗼𝗼𝗻: Link in bio! 30th May - 1st June 🗣️ Friday | Conference @ UCL | 𝗔𝗹𝗺𝗼𝘀𝘁 𝘀𝗼𝗹𝗱 𝗼𝘂𝘁 - 𝘀𝗲𝗰𝘂𝗿𝗲 𝘆𝗼𝘂𝗿 𝘀𝗽𝗼𝘁 🔴 Sat-Sun | In-person Unconference | 𝗦𝗢𝗟𝗗 𝗢𝗨𝗧 💻 Sat-Sun | Virtual Unconference | 𝗧𝗶𝗰𝗸𝗲𝘁𝘀 𝗮𝘃𝗮𝗶𝗹𝗮𝗯𝗹𝗲
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Important analysis of the global burden of cluster headache pain, applies our proposed suffering metrics YLSS (Years Lived with Severe Suffering) and DLES (Days Lived with Extreme Suffering) @FeliciaKnaul @Cluster_buster @PainNewsNetwork
🧬 New publication alert: "Quantifying the Global Burden of Extreme Pain from Cluster Headaches" by Alfredo Parra @alfredoparrah in collaboration with the Qualia Research Institute @QualiaRI A deep dive into why current health metrics catastrophically fail at measuring extreme suffering, based on analysis of 30+ years of clinical data across 24 countries. Let me explain why this matters. 🧵 (1/15)
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Support us and our work to promote compassionate governance and effectively address some of the worst forms of suffering. Our autumn fundraiser: gofundme.com/f/kymdqc-opis-a…
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We are currently running a unique, large-scale survey to assess suffering due to a wide range of life conditions. Please consider participating and sharing widely! Info & link on this page: preventsuffering.org/metrics… #PublicHealth #MentalHealth #Wellbeing
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OPIS is conducting a survey to gather information about suffering caused by a wide range of conditions, including intensity & duration. Anyone who has experienced significant suffering, past or present, can participate. 5-15 min to complete docs.google.com/forms/d/e/1F…
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As a result of a partnership we initiated 3 years ago with @TheraPsil, Health Canada has provided legal access to psilocybin for the first cluster headache patient. We are hopeful that the barriers to access will continue to fall everywhere. preventsuffering.org/wp-cont…
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Dr Nimrod Rosler from @TelAvivUni on the psychology of conflict & strategies to shift attitudes in Israel-Palestine, speaking at a peacebuilding retreat we co-organised in Greece in April @cfpeace youtube.com/watch?v=__cVJrD5…
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Our case study showing that ayahuasca and other psychedelics suspended symptoms in a patient with an agonising headache condition called SUNCT
Clinical correspondence: @JonLeighton1 et al share a case of suspension of Short-lasting, Unilateral, Neuralgiform #headache attacks with Conjunctival injection & Tearing (#SUNCT) symptoms with #ayahuasca & serotonergic #psychedelics headachejournal.onlinelibrar…
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My talk at EAGxAustralia in September 2023 on prioritising the urgency of suffering youtube.com/watch?v=4M5fgkWW…
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My conversation with @JamieWoodhouse for the @Sentientism podcast is now out. We discuss core questions like What's real?, What matters?, Who matters?, and finally, How to make a better world? @OPISOrg youtube.com/watch?v=Lddo2sTX…
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So many wonderful quotes from our upcoming #Sentientism episode with @JonLeighton1 @OPISOrg 🤩 "...without subjective experience there's nothing for anything to matter to." "This is what makes suffering unique... suffering is a state of being that inherently calls for action."
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The recording of our webinar is available here: youtube.com/watch?v=ZSDrGfyP…
Join us on 17 Jan for a webinar (link: bit.ly/zoomco17) with 4 visionaries on building peace in Israel-Palestine. @maozinon @2states1homelan @omdimbeyachad @cfpeace @ALLMEP @ThePCFF @peacenowisrael @WomenWagePeace
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Join us on 17 Jan for a webinar (link: bit.ly/zoomco17) with 4 visionaries on building peace in Israel-Palestine. @maozinon @2states1homelan @omdimbeyachad @cfpeace @ALLMEP @ThePCFF @peacenowisrael @WomenWagePeace
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