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I suspect this is damage control. Doctors are not happy with UTC.
$LQDA didn't lose and that will be clear in the future. $380M to drop all litigations was worth it, risk removed completely.
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$MDGL Analysts question whistleblower allegations against Madrigal
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$KURA The most undervalued commercial onco-play?
Late 2025 approved AML drug ziftomenib is rapidly gaining traction: Q2 sales $9.1M (+57% QoQ), and they already have the majority of new starts in r/r NPM1m AML (per Kura). IMO, investors have underestimated the once-daily dosing vs $SNDX twice-daily + potential cardiac safety edge.
The biggest upside is still frontline AML: $350-400M current US TAM vs $7B expanded TAM. Mgmt sees $3B peak sales potential. ASH (abstracts Nov 4): possible aza/ven durability, FLT3 combos & broader AML data. Earlier 96% CRc with ziftomenib + 7+3. Durability will be a key, a lot to expect for esp. updated data at ASH in dec.
Risks: J&J bleximenib (Ph3, update schedule not given) & $SNDX competition.
A great commercial play with significant upsise, and if the frontline data holds up, we are looking at 3x-10x the valuation. CEO just having bought shares twice and talked about adding also reassures the long term theses.
Next catalyst: earnings and ASH abstracts both in two weeks.
Do your own DD.
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$TGTX Prakhar - Positioning seems long into earnings, as investors noted to us that third-party data sources, such as claims data, suggest a strong Q3
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$LQDA $xbi
Good news, and a victory for reasonableness.
A good outcome all around, and especially for patients — global settlement:
> Fully resolves all six ongoing lawsuits between the companies
> Maintains uninterrupted access to YUTREPIA® for patients with pulmonary arterial hypertension (PAH)
> Liquidia (LQDA) to pay net $380.7 million in multiple installments in 2026 and 2027, inclusive of payments to resolve antitrust litigation against United Therapeutics
> Strong financial position with $222.7 million in Q3’26 YUTREPIA net product sales (preliminary, unaudited), contributing to $396.1 million in cash and cash equivalents as of September 30, 2026
> Liquidia will continue to advance YUTREPIA and L606 clinical programs as previously outlined
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In 15 months $nktr has gone from
$8 to $37
$37 to $21
$21 to $65
$65 to $33
$33 to $73
$73 to $62
$62 to $109
$109 to $54
$54 to $77
$77 to $43
This latest move is “not different this time”.
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$CGEM initiates NDA submission for Zipalertinib in NSCLC under FDA’s Real-Time Oncology Review (RTOR) program
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Sometimes the ugliest headlines make for the most interesting entry points.
Case in point: $LQDA — Liquidia.
The stock closed at $30.26 after falling 57% yesterday and is now around $25.32 pre-market.
I spent this morning going through the decision, the numbers, some of the relevant patent case law, and the new sell-side work.
My conclusion: the headline looks considerably worse than the range of plausible economic outcomes.
Here’s how I’m thinking about it 🧵👇
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I find the Judge's reasoning on Claim 1 & Claim 14 very weird wrt $LQDA . Why would he say he was considering a motion to strike based on Rule 37 and probe the backdating and then do this?
In his opinion he says LQDA had adequate notice because common ownership was mentioned thrice in the pre-trial package and that was adequate disclosure.
Ok, so common ownership was mentioned thrice in 1,400 page pre-trial briefs. Two of those mentions were $UTHR saying they had common ownership, the third mention was them actually promising to produce proof of it.
LQDA submitted an interrogatory asking for said proof a full year even before the pre-trial package. UTHR never responded to that and the three responses the came later as I mention above, once again provide absolutely no proof at all.
For some reason Judge found this disclosure not only adequate but he also then accepted Byrd’s trial testimony as proof.
He resolved by accepting UTHR’s argument that managing Orange Book patents falls within Byrd’s disclosed regulatory responsibilities. He therefore found that LQDA had adequate notice of the subject.
But does familiarity with FDA patent listings necessarily establish knowledge of who owned the underlying inventions on particular historical dates?
All this while UTHR still had disclosure obligations, and Byrd needed a basis for personal knowledge.
I get that the law is blind, but can it blind to such an extent? The tricks played by UTHR in this case have already imo changed the IP litigation landscape.
What's to stop someone from doing the same underhanded things and citing Richard G. Andrews?
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Pretty good handicap outcome scenario for $LQDA $UTHR from sharp sell side analyst
Per legal KOL feedback, both parties have 1 week to agree on the injunction.
Our KOL doesn't expect LQDA to push back on this point, as they would likely want a cooperative Judge as they seek a skinny PAH label.
Appeal?
Both companies had said previously that they planned to appeal in a loss scenario.
Our legal KOL believes that LQDA's path to eventually winning requires the same strategy, which is to challenge the '793 patent as admissible prior art. However, the legal KOL thinks Judge Andrews conveyed that the issue of '793 admissibility was clear during the trial which he presided over, and thus he thinks it will be difficult for an appellate court to conclude this was not the case.
What happens next?
High probability - UTHR and LQDA reach agreement on injunction for judge to sign w/in a week, though the financial penalty (e.g., damage compensation, potential royalty) will be calculated later. The injunction should also provide clarity as to whether exiting Yutrepia PH-ILD patients will be allowed to stay on Yutrepia.
Low probability - if they do not agree on an injunction, we understand that the Judge may step in himself and give an injunction regardless.
What are the damages, and could there be a deal? Our KOL expects the economic value of the damages will be rooted in the lost profit to UTHR, of each Yutrepia unit sold for PH-ILD. Thus, if there is a royalty deal, we would expect it to likewise reflect this value. The value of a royalty is that it may be easier logistically, but we would expect this to also contemplate UTHR's lost profit to future PH-ILD through '327's expiry (~2042).
LQDA stock impact - We think LQDA shares could trade to the high $30's near term in this scenario. Per our model, removing future PH-ILD from Yutrepia lowers our Yutrepia value to $24/sh, though we anticipate some credit for L606.UTHR stock impact - We had been anticipating +5-10% in this scenario.
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We think that today or tomorrow are potential decision days for Andrews. He had 3 bench trials during this last term that were unresolved as of a week ago. He resolved one of them on Friday. He has still has the $LQDA case and the $WBD case. He has never had a bench trial appear on the CJRA list twice, which both of these would if we extend passed Wednesday.
It seems highly unlikely that he has a third clerk look at the $LQDA case (or the $WBD case), which means that we likely already have an opinion done. Perhaps there are some tweeks left but he has in the past shown that this CJRA deadline is meaningful (see below) with rulings coming slightly before and then the day of.
Let this long wait finally be over.
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$ABVX Combination strategy and next-generation pipeline updates expected around JPM
Q1 2027 should be very eventful
RT @seedy19tron: *** $nktr vs $lly breaking
3 more notes passed from jury this morning, feedback from sources on ground was they leaned po…
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Wall Street Jumped the Gun: The Big Overread in Nektar v. Lilly
On Tuesday, when the jury asked Judge Donato to clarify the difference between finding a breach with $1 in nominal damages versus finding no breach at all, Wall Street treated a single note as the verdict. Nektar ($NKTR) stock came under pressure on the headline: the Jury is letting Lilly ($LLY) walk.
Treating one note from an 8-person panel as the unanimous voice of the jury is a massive overread - especially in San Francisco.
Wall Street assumed a jury will take the simplest path. A San Francisco jury hasn’t appeared to do that. The Jury pool is drawn from a sophisticated Bay Area demographic with an unusually high understanding of data integrity issues. They understand the difference between a typo and a systemic review failure. The two notes this jury sent show that sophistication.
Tuesday's note at the roughly 13-hour mark confirms the $0-to-$1 outcome is being discussed, but it doesn't dictate direction.
Instructions 13 and 15 create a fork: Instruction 13 says Nektar must prove Lilly failed to use Commercially Reasonable Efforts and that it sustained damages, while Instruction 15 says damages must be reasonably certain. A jury that believes Lilly breached CRE but is divided on whether Nektar proved its full damages with reasonable certainty naturally asks: does that uncertainty force us to flip to no breach?
Donato's answer gave them permission to keep liability intact - breach with nominal is a finding of liability, no breach is not. That clarification is most useful to a panel that is coalescing around breach and is trying to preserve that finding while it works through damages.
The sentence the market ignored
One potential reason the jury may have spent another 10-plus hours after that instead of going home is in Instruction 15 itself:
"It is for you to determine what damages, if any, have been proved... When the existence of damage is certain and the only uncertainty is as to its amount, Nektar may not be denied recovery as long as it shows a stable foundation for a reasonable estimate of damages."
That is the opposite of a $1 trap. It instructs the jury they are forbidden from denying recovery if there is a stable foundation, even if they reject the exact expert number.
The sushi test: why Jury’s other questions matters so much
Late Wednesday, at roughly the 24 hours of deliberations mark, the jury asked (paraphrased): “If a business works with a company that you know is at a higher risk of inaccurate data, is that business' normal data-review efforts reasonable with the known risks?"
Think of it like a sushi restaurant.
You normally trust your fish delivery and do a quick smell test. Then you learn your supplier just had two FDA warnings for spoilage. Is it still "reasonable" to do the same quick smell test? No. A reasonable owner starts opening boxes, checking temps, may even consider switching suppliers. Doing "what you usually do" when you know risk is higher is the definition of unreasonable.
That is exactly what is at issue under CRE. Under the Agreement, Lilly is liable for PRA's acts and omissions, including the miscalculation that reported Rezpeg's efficacy at 66% at EADV 2022 when the corrected data showed 83%. Lilly's defense has been "we did what we normally do for comparable products."
This jury - a Bay Area jury that lives with QA - is asking whether normal is still reasonable when you are on notice that your data source is high-risk.
If they believed standard oversight was sufficient to satisfy CRE, they would have returned a defense verdict. Instead, they are testing whether Lilly's failure to add safeguards when it knew risk was elevated.
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$NKTR
Lots of funky action in this name the past few days, some specific to the ongoing court case and some from bio as a whole. Let's unpack it.
The jury note, paraphrased as "Is there a difference between breach + $1 and no breach + $0?", spooked the market and sent the stock down sharply. Two sides to this.
First, the note is informative, but only a little. It tells us at least one juror sees the $0/$1 outcome as part of their possible resolution space. Where I think the market (or at least fintwit) got it wrong is treating the note as the voice of the entire jury. It could reflect the whole panel, or it could be a single juror's question. It doesn't even tell us direction: it could come from a juror looking for a way to find breach despite doubting the damages case. The price action implied the whole jury is now choosing between $0 and $1, which I think is a big overread.
Second, this is NKTR: a retail/fintwit-heavy, relatively illiquid SMID-cap biotech that moves 5% on a random Tuesday with no news. A 10% move on this headline looks extreme, but near-term price action here mostly reflects value-agnostic traders playing local news and liquidity flow, not a considered repricing of long-term value.
The bigger picture: the case is largely a distraction from the real value, which is Rezpeg. I'm not a biotech expert, but the sell side and most biotech specialists I respect see it as a likely viable commercial product that's underpriced here. If anything, the case matters mainly as an overhang. An uncertain $0-to-$1B+ claim is hard for any acquirer or partner to price, so resolution in almost any direction clears the path for corporate action.
The distraction is creating the opportunity.
Disclosure: Creek Drive and its affiliated funds holds a long position in NKTR. Views expressed are current opinions for information only, subject to change and are not investment advice or a recommendation to buy or sell any security. Investing involves the risk of loss and past performance is not indicative of future performance. See the disclosures link in my bio for more important information.
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$NKTR v $lly
No verdict today. Getting closer to AA data which might be a good thing. Anyways, Jury back tomorrow.
They’re now into their 4th day. And shame the stocks given up nearly $200m in mc on a simple question jury asked. Just goes to show how broken mechanics are right now across the board. A jury that settled on $1 nominal after Tue's note would have been done by now. More likely they're working through liability and the damages number, which needs to be unanimous.
Nothing to do but wait.
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$NKTR Oct 1 DATA ORAL presentation pagv3.virtual-meeting.org/ea…























