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Membrane Protein Bioreagents, Gene-to-Protein CRO, Genetic Diagnostics

Mountain View, CA
Joined January 2013
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And for more on applications of machine learning in drug discovery and development, here's a recent review go.nature.com/2GgbGuK
ProNovus Bioscience retweeted
Just had coffee with a friend and biotech CEO. They’re moving operations out of the Bay Area and California entirely, decamping for sites back East, eg RTP. It’s gotten to the point where you have to be a Pharma or enjoy setting cash on fire to operate a lab in the Bay Area.
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Deadly Superbugs Win as Wall Street Flees Makers of Antibiotics bloom.bg/304uzI8
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New computational tool enables powerful molecular analysis of biomedical tissue samples rna-seqblog.com/new-computat…
The trickster microbes that are shaking up the tree of life, from @nature nature.com/articles/d41586-0…
ProNovus Bioscience retweeted
Fierce competition among biosimilar manufacturers in China, India and South Korea means they are outcompting Western biosimilar manufacturers in low-income markets go.nature.com/2PWYnmd
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Antibiotic mechanisms are revealed by a white-box machine-learning approach that integrates biochemical screening and metabolic network modeling. #NBThighlight bit.ly/2HcX4eV
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ProNovus Bioscience retweeted
These 6 biotech stocks are promising takeover targets dlvr.it/R3xjly
ProNovus Bioscience retweeted
.@NIH is seeking public comments on future plans for the #BRAINInitiative. Submit your input here: bit.ly/2Gl6fK5 #studyBRAIN
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Great review on tractability of allosteric binding sites on GPCRs informed by x-ray structures ncbi.nlm.nih.gov/pubmed/3099…
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“Everyone agrees that there is an absolute need for new antibiotics but there is no sustainable market,” @IFPMA’s Thomas Cueni warns on the growing threat of antimicrobial resistance. buff.ly/2LeTpmf
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.@deevybee urges researchers to rein in the four horsemen of the reproducibility apocalypse: publication bias, low statistical power, P-value hacking and HARKing. go.nature.com/2L0zWpr
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Two new studies report the first cryo-EM structures of a GABAA receptor in a physiological conformation and in complex with various drugs. These structures could provide the basis for future structure-based drug discovery. go.nature.com/2QD9wY7 @RaduAricescu and @MRC_LMB
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Researchers develop a method to investigate how bacteria respond to starvation and to identify which proteins bind to the “magic spot” — ppGpp. Explore in 3D at RCSB PDB: rcsb.org/structure/6CZF news.mit.edu/2018/mit-biolog…
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Advanced biomaterials and drug delivery systems could improve the potency of cancer immunotherapies while reducing toxicities - find out more in this new review by Rachel Riley, Carl June, Robert Langer and Michael Mitchell go.nature.com/2TG3c4f