ProNovus Bioscience (@ProNovusBio) header
ProNovus Bioscience (@ProNovusBio) profile picture

ProNovus Bioscience

@ProNovusBio

Membrane Protein Bioreagents, Gene-to-Protein CRO, Genetic Diagnostics

 Mountain View, CA
pronovusbio.com
Joined January 2013
  • Tweets602
  • Following656
  • Followers319
15Media
Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)Photo by ProNovus Bioscience (@ProNovusBio)
And for more on applications of machine learning in drug discovery and development, here's a recent review go.nature.com/2GgbGuK
Image from Nature Reviews Drug Discovery (@NatRevDrugDisc)
28
1
50
ProNovus Bioscience retweeted
Ethan Perlstein 1-to-N (@eperlste) profile picture
Ethan Perlstein 1-to-N
@eperlste8 Jul 2019
Just had coffee with a friend and biotech CEO. They’re moving operations out of the Bay Area and California entirely, decamping for sites back East, eg RTP. It’s gotten to the point where you have to be a Pharma or enjoy setting cash on fire to operate a lab in the Bay Area.
16
17
3
173
ProNovus Bioscience retweeted
SynBioBeta (@SynBioBeta) profile picture
SynBioBeta
@SynBioBeta15 May 2019
Gene Hackers: The Young #Biotech #Entrepreneurs Looking To Make Billions By Editing Life Itself bit.ly/2Q3Vnok @ellie_kincaid @mtindera07 #geneediting #genomeediting #CRISPR #synbio @CaribouBio @eGenesisBio @mammothbiosci
8
15
ProNovus Bioscience retweeted
Big4Bio (@big4bio) profile picture
Big4Bio
@big4bio15 May 2019
#Biotech companies raised $16.8 billion in #venturecapital in 2018 compared to $12.1 billion in 2017. Additionally, the average amount per round of financing was 42 percent more than in 2017. fiercebiotech.com/special-re…
Biotech's top 10 money raisers of 2018

Biotech's top 10 money raisers of 2018

If 2017 was a banner year for biotech venture capital, 2018 blew it out of the water. Last year, private biotech companies reeled in a grand total of $16.8 billion, eclipsing 2017’s then-record $12.1...

fiercebiotech.com
1
ProNovus Bioscience retweeted
Kelly A. Hogan Ph.D. (@Loose_Lab_Rat) profile picture
Kelly A. Hogan Ph.D.@Loose_Lab_Rat15 May 2019
New computational tool enables powerful molecular analysis of biomedical tissue samples rna-seqblog.com/new-computat…
1
ProNovus Bioscience retweeted
Fiona Marshall (@FionaHMarshall) profile picture
Fiona Marshall@FionaHMarshall14 May 2019
Fascinating paper on changes in levels of mGlu5 in PTSD linked to suicidal thoughts. Potential biomarker and pathway for treatment. pnas.org/content/early/2019/…

In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation | PNAS

Recent evidence implicates dysregulation of metabotropic glutamatergic receptor 5 (mGluR5) in pathophysiology of PTSD and suicidality. Using positr...

pnas.org
7
17
ProNovus Bioscience retweeted
Nature Biotechnology (@NatureBiotech) profile picture
Nature Biotechnology
@NatureBiotech9 May 2019
Fierce competition among biosimilar manufacturers in China, India and South Korea means they are outcompting Western biosimilar manufacturers in low-income markets go.nature.com/2PWYnmd
Image from Nature Biotechnology (@NatureBiotech)
3
5
ProNovus Bioscience retweeted
Nature Biotechnology (@NatureBiotech) profile picture
Nature Biotechnology
@NatureBiotech9 May 2019
Antibiotic mechanisms are revealed by a white-box machine-learning approach that integrates biochemical screening and metabolic network modeling. #NBThighlight bit.ly/2HcX4eV
24
56
ProNovus Bioscience retweeted
cafepharma (@cafepharma) profile picture
cafepharma@cafepharma2 May 2019
These 6 biotech stocks are promising takeover targets dlvr.it/R3xjly
1
ProNovus Bioscience retweeted
NIH NCCIH (@NIH_NCCIH) profile picture
NIH NCCIH@NIH_NCCIH1 May 2019
.@NIH is seeking public comments on future plans for the #BRAINInitiative. Submit your input here: bit.ly/2Gl6fK5 #studyBRAIN
5
4
ProNovus Bioscience retweeted
Fiona Marshall (@FionaHMarshall) profile picture
Fiona Marshall@FionaHMarshall21 Apr 2019
Great review on tractability of allosteric binding sites on GPCRs informed by x-ray structures ncbi.nlm.nih.gov/pubmed/3099…
12
28
“Everyone agrees that there is an absolute need for new antibiotics but there is no sustainable market,” @IFPMA’s Thomas Cueni warns on the growing threat of antimicrobial resistance. buff.ly/2LeTpmf
3
4
ProNovus Bioscience retweeted
Nature Portfolio (@NaturePortfolio) profile picture
Nature Portfolio
@NaturePortfolio24 Apr 2019
.@deevybee urges researchers to rein in the four horsemen of the reproducibility apocalypse: publication bias, low statistical power, P-value hacking and HARKing. go.nature.com/2L0zWpr
69
7
109
Two new studies report the first cryo-EM structures of a GABAA receptor in a physiological conformation and in complex with various drugs. These structures could provide the basis for future structure-based drug discovery. go.nature.com/2QD9wY7 @RaduAricescu and @MRC_LMB
Image from Nature Reviews Drug Discovery (@NatRevDrugDisc)
10
18
Top product forecasts for 2019 @ByLisaU @EvaluatePharma go.nature.com/2Hc7OO8
Image from Nature Reviews Drug Discovery (@NatRevDrugDisc)
1
40
7
46
Researchers develop a method to investigate how bacteria respond to starvation and to identify which proteins bind to the “magic spot” — ppGpp. Explore in 3D at RCSB PDB: rcsb.org/structure/6CZF news.mit.edu/2018/mit-biolog…
RCSB PDB - 6CZF: The structure of E. coli PurF in complex with ppGpp-Mg

RCSB PDB - 6CZF: The structure of E. coli PurF in complex with ppGpp-Mg

The structure of E. coli PurF in complex with ppGpp-Mg

rcsb.org
6
2
12
Advanced biomaterials and drug delivery systems could improve the potency of cancer immunotherapies while reducing toxicities - find out more in this new review by Rachel Riley, Carl June, Robert Langer and Michael Mitchell go.nature.com/2TG3c4f
Image from Nature Reviews Drug Discovery (@NatRevDrugDisc)
24
2
31
ProNovus Bioscience retweeted
Hideaki E. Kato (@emeKato) profile picture
Hideaki E. Kato@emeKato3 Dec 2018
human TP bound to two antagonists, ramatroban and daltroban nature.com/articles/s41589-0… human EP3 bound to misoprostol-FA nature.com/articles/s41589-0… human EP3 bound to endogenous ligand PGE2 nature.com/articles/s41589-0… 今週のNCBはclass A GPCRの新規構造祭り。
Structural basis for ligand recognition of the human thromboxane A2 receptor

Structural basis for ligand recognition of the human thromboxane A2 receptor

Nature Chemical Biology - Structures of the human thromboxane A2 receptor, a member of the prostanoid family of G-protein-coupled receptors, in complex with two synthetic antagonists reveal that...

nature.com
5
6
17
NMR can be used to study biased GPCR ligands in drug discovery, providing dynamic information that complements insights from X-ray and cryo-EM structures - find out more in this review go.nature.com/2yZiAkg
Image from Nature Reviews Drug Discovery (@NatRevDrugDisc)
12
2
21
ProNovus Bioscience retweeted
Hideaki E. Kato (@emeKato) profile picture
Hideaki E. Kato@emeKato5 Sep 2018
New release2 6CSM "Crystal structure of the natural light-gated anion channel GtACR1" Kobilka & Deisseroth labs. Nature.
1
4
1
11
Load more