Dissecting the Tumour Specificity of Cancer Drivers @CRUKresearch Grand Challenge team funded in partnership with @TheMarkFdn
Joined April 2019
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SPECIFICANCER retweeted
Fascinating latest findings from @cancergrand @SpecifiCancer team exploring how cancers in different parts of the body use unique strategies to avoid attack by the immune system. This innovative thinking could lead to more effective cancer treatments cancergrandchallenges.org/ne…
SPECIFICANCER retweeted
A year of scientific creativity: check out Discover, our annual progress magazine showcasing the exciting discoveries our global community of teams have made over the past year:
bit.ly/2WcKMyE
#CancerGrandChallenges #sciencenews
SPECIFICANCER retweeted
We found that one of the reasons why Apc is a potent tumour suppressor in the intestine is that once it’s lost in a stem cell, notum a wnt target gene will inhibit wnt signalling in neighbouring stem cells. This allows Apc mutant cells to “win”. More details in Dusty’s thread
How do mutants win the game of clones? 🏆🤷
In this week's @Nature, Dustin Flanagan @CRUK_BI + @owen_sansom, with the great @KatajistoLab and @SPECIFICANCER team, find out how APC mutations cause #cancer in the #gut ... with help from NOTUM
A 🧵by Dustin
1/11
SPECIFICANCER retweeted
How do mutants win the game of clones? 🏆🤷
In this week's @Nature, Dustin Flanagan @CRUK_BI + @owen_sansom, with the great @KatajistoLab and @SPECIFICANCER team, find out how APC mutations cause #cancer in the #gut ... with help from NOTUM
A 🧵by Dustin
1/11
SPECIFICANCER retweeted
Congratulations to @SpecifiCancer and @KatajistoLab on their latest discovery in @nature! The team identified the molecule Notum as a key player in the early stages of apc-driven #colorectalcancer. - bit.ly/3nrHyAN @owen_sansom @CRUK_BI #specificancer
SPECIFICANCER retweeted
Amy Schade and Karen Cichowski of our SPECIFICANCER team discuss the importance of mentorship. Amy joined Karen's lab (@BrighamWomens) as a postdoctoral research fellow in 2019.
Find out more about their relationship: bit.ly/3cw4o5h
SPECIFICANCER retweeted
The @KevinHaigisLab and @peter_j_park labs show that KRAS mutations across multiple cancer types have allele- and tissue-specific mutagenic origins, comutation patterns, and dependency interactions
go.nature.com/3lHkoFv
#cancerresearch @NatResCancer
Check our second advocate/scientific team's conversation video. Patient advocate, @helenkmatthews interviewed @owen_sansom, a professor of @CRUK_BI and the @UofGlasgow. @owen_sansom talked about how he has approached the team's scientific goal.
specificancer.org/team-conve…
SPECIFICANCER retweeted
You don't need to be a cancer researcher to lead a #CancerGrandChallenges team - we're looking for new thinking from diverse teams to address our challenges.
Download our Expression of Interest guidelines to find out how you can apply your expertise: cancergrandchallenges.org/re…
Team's patient advocate representative, Fran Visco has invited two leading scientists, Dr. Elledge and Dr. Cichowski to the conversation. They explained the team's research to the public.
Watch “Specificancer Interview” on #Vimeo vimeo.com/480478214?ref=tw-s…
SPECIFICANCER retweeted
Meet the #CancerGrandChallenges teams
#SPECIFICANCER led by Prof Stephen Elledge are unravelling the riddle of #tissuespecificity in cancer, to ensure cancer types are best matched to therapies for increased #patientbenefit. Co-funded by @TheMarkFdn.
cancergrandchallenges.org/te…
SPECIFICANCER retweeted
#CancerGrandChallenges partnership between @CR_UK and NCI has been ceremonially signed. “The two largest funders of cancer research unite to define a new era in research and discovery for the future benefit of patients with cancer.” – Dr. Iain Foulkes @Iain_CRUK @NCIDirector
SPECIFICANCER retweeted
PhDs @BeumerJoep and @jeltevdvaart from the group of @HansClevers set up collaboration with to show that #SARSCoV2 may infect cells in the intestine. Just out in @ScienceMagazine!
New research in Science reveals that #SARSCoV2 can infect and replicate in cells that line the human intestine, helping to explain why some #COVID19 patients experience gastrointestinal symptoms. Learn more: fcld.ly/qh61e9b
SPECIFICANCER retweeted
To prevent the spread of #COVID19, HHMI Investigator Steve Elledge’s lab has emptied out. However, he, Nouran Abdelfattah (@Abdelfattah_NS) (shown), & six other researchers have continued working in person, under new safety rules, studying the coronavirus: bit.ly/2XlVyAZ
SPECIFICANCER retweeted
Today is #GivingTuesdayNow, a global day of unity and giving. The #coronavirus outbreak has slowed us down, but we will never stop. If you can, please visit bit.ly/2W3fis5 to make a donation towards our life-saving research
SPECIFICANCER retweeted
Three new studies from @KevinHaigisLab at @BIDMChealth have revealed that cancer disease incidence and severity are influenced by the specific type of #KRAS mutation, as well as by the tissue in which the mutation is located. bit.ly/2ZVv4bk
SPECIFICANCER retweeted
Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation cell.com/cell-systems/fullte…
SPECIFICANCER retweeted
We’re committed to equality, diversity and inclusion in everything that we do. Because cancer doesn’t discriminate. This year, we’re celebrating #Pride Month by sharing what Pride means to our staff and supporters. For more info visit po.st/u5yTTn #PrideinResearch
SPECIFICANCER retweeted
Fran keeps our #CRUKGrandChallenge science focused on the wellbeing of the patients. Listen below👇 and read more here 👉 : po.st/89AKJr
@SpecifiCancer team had a successful video meeting. Collaborative research team moves forward to the goal.
