SerpellLab (@SerpellLab) profile picture

SerpellLab

@SerpellLab

Research groupworking on molecular basis of Neurodegeneration and Alzheimer's disease. Dementia research group. Supported by Alzheimer's society and ARUK

Joined May 2016
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Thank you to @SerpellLab for their @alzheimerssociety guest blog discussing what the Alphafold artificial intelligence programme from @DeepMind could mean for #dementia research - early days but an important step alzheimers.org.uk/blog/can-a…
How artificial intelligence can help people affected by dementia

How artificial intelligence can help people affected by dementia

Artificial intelligence technology could be a game-changer for people affected by dementia. Find out why Alzheimer’s Society is supporting research in this area.

alzheimers.org.uk
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#Tau is a protein associated with many #brain diseases, including #Alzheimer's. @TauRx believe #education is essential in spreading awareness and understanding of how tau and Alzheimer's disease are connected. Learn more here #targetingtau ➡️ shorturl.at/xyK35
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Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuroscience frontiersin.org/articles/10.…
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I’m looking for a Phd student to join my lab at @SussexNeuro @SussexLifeSci in September 2021, to study the modulation of early visual processing by behaviour and neuromodulation. 👉bit.ly/3lcduHn But there is more...
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👏Highlighted in our new issue: #AmyloidBeta 1-42 internalisation and toxicity are influenced by conformation and assembly state rather than size. Study by @KarenEMarshall @Serpell1 & colleagues →bit.ly/38vXYCO #neurodegeneration #Alzheimers @Serpelllab @SussexNeuro
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Read @cathnaledi ‘s latest blog all about our #mrc funded research project investigating blood flow and #Alzheimers ! 🧠
Sussex Psychology (@Sussex_Psych) profile pictureSussex Psychology@Sussex_Psych10 Nov 2020
Do bad blood vessels trigger #Dementia? @BrainEnergyLab is trying to understand how changes in blood vessels in the brain are linked to the onset of #Alzheimer’s disease. Find out more about their research in our latest blog: ow.ly/IhjS50Cgldc
Image from Sussex Psychology (@Sussex_Psych)
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We're excited to announce this year's virtual Carols at Christmas concert (Thursday 17 Dec) will include a performance by musician Paul Harvey! We would love for you to join us! Book your free ticket today: bit.ly/3dIvFBu (with thanks to @mrnickharvey for the video).
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Our latest paper investigating the structural polymorphism of #amyloid fibrils is now published with @SpringerNature in @CommsChem :) we use AFM to reconstruct and quantify amyloid polymorphism: rdcu.be/b64Ar @LDAubrey @LiisaLutter @CJSerpell @psinomore @SerpellLab
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PostDoc position in Cryo-EM of Neurodegeneration in our group at the EPFL, Lausanne, Switzerland. We offer excellent working conditions with outstanding equipment in a beautiful city at the Lake of Geneva. More info at epfl.ch/labs/lbem/open-posit…
Image from Henning Stahlberg (@LabStahlberg)
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Can we distinguish seeding through templated elongation, where the specific conformation encoded by amyloid fibrils is propagated, from a more generic surface-catalysed seeding mechanism? Yes we can, our new manuscript shows how we did it 😊🔬💡: biorxiv.org/cgi/content/shor… 2/2
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We have two open possitions in the lab. A permanent Senior Lab Research Scientist (a mix of a permanent postdoc and lab manager) and a Postdoc. We investigate how neural circuits function and evolve using a multidisciplinary approach. For more info: prietogodinolab.org/team/joi…
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Crazy to think I can call myself an author! It's finally out onlinelibrary.wiley.com/doi/… Thank you so much to @Eddi34165646 @AndHaze #tauteam @UKDRI @SchiavoMNPlab Knockin’ on heaven’s door: Molecular mechanisms of neuronal tau uptake
Knockin’ on heaven’s door: Molecular mechanisms of neuronal tau uptake

Knockin’ on heaven’s door: Molecular mechanisms of neuronal tau uptake

The pathological spread of tau in Alzheimer's disease and other tauopathies follows a stereotypical pattern in the brain, proposed to occur via a prion-like trans-synaptic transfer. However, the...

onlinelibrary.wiley.com
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📣The deadline to apply for the ARUK David Hague Early Career Investigator of the Year 2021 is fast approaching. Applications must be submitted before the 25 September to be in with a chance of winning. Good luck! alzheimersresearchuk.org/for…
Image from ARUK Thames Valley Network (@ARUKThamesV)
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Interesting. It seems that GFPs bind amyloid structures. Sequence-independent recognition of the amyloid structural motif by GFP protein family pnas.org/content/early/2020/…
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Excited to see this update on #EuroTau. Great timing, hopefully things would have normalised by then – at Brighton, England
Luc BUEE (@LucBuee) profile pictureLuc BUEE@LucBuee25 Aug 2020
Great News : Eurotau 2021 will be held in Lille on October 26-27, 2021. Please stay tune for further information #eurotau @RCFNeuro @alzassociation @adpdnet
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We are hiring! Are you looking for a #postdoc in #Alzheimer's research? Do you love #neuropathology and #proteomics? Do you want to live in #NewYorkCity and work at the amazing NYU Langone? Then this job is for you - apply now jobs.sciencecareers.org/job/…
Post Doctoral Fellow in Alzheimer's Research - New York City, New York (US)

Post Doctoral Fellow in Alzheimer's Research - New York City, New York (US)

Postdoc position at NYU to study the role of apoE in Alzheimer's using a combination of neuropathological, proteomic and cell culture techniques.

jobs.sciencecareers.org
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Very grateful to anyone who can help Jamie out with his PhD project. Sorry, I know people have received many requests, but solidarity to all empiricists who have had to change to online testing due to COVID. RTs much appreciated.
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SerpellLab retweeted
Luc BUEE (@LucBuee) profile picture
Luc BUEE@LucBuee12 Aug 2020
Replying to @mahmoudbukar
@mahmoudbukar Eurotau is planned In Lille (if possible) but a virtual meeting is also on discussion. Thanks to @RCFNeuro #eurotau
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In the #chatathon 13:30-13:45 slot I'm joined by @TJParry from @AlzResearchUK. Tim is going to tell us all about some of their amazing work, and how they make your money work to find a breakthrough. See the full schedule at chatathon.uk raising £ for @AlzResearchUK
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These are exciting times for the North East of Scotland @Opportunity_NE1, with significant plans for investment in #lifesciences #targetingtau #dementia #Aberdeen
Opportunity North East (ONE) (@Opportunity_NE1) profile pictureOpportunity North East (ONE)@Opportunity_NE113 Aug 2020
North east Scotland is home to 75% of Scotland's late-stage drug discovery companies, including @TauRx - a global leader in Alzheimer's research, drug discovery, development & diagnostics. Industry's goal is to grow the company base 100% #ONELifeSciences #lifesciences #Aberdeen
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