Research groupworking on molecular basis of Neurodegeneration and Alzheimer's disease. Dementia research group. Supported by Alzheimer's society and ARUK
Joined May 2016
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We were really excited to write this short article for @alzheimerssoc about AlphaFold2. Lovely work @KarenEMarshall alzheimers.org.uk/blog/can-a…
SerpellLab retweeted
Thank you to @SerpellLab for their @alzheimerssociety guest blog discussing what the Alphafold artificial intelligence programme from @DeepMind could mean for #dementia research - early days but an important step alzheimers.org.uk/blog/can-a…
SerpellLab retweeted
#Tau is a protein associated with many #brain diseases, including #Alzheimer's. @TauRx believe #education is essential in spreading awareness and understanding of how tau and Alzheimer's disease are connected.
Learn more here #targetingtau ➡️ shorturl.at/xyK35
Delighted with this newly submitted paper!
Read our new work from @SerpellLab using PHF-core Tau fragment, showing that oxidative stress conditions that induce dityrosine crosslinking lead to the trapping of Tau intermediates, preventing them from transforming into fibrils.
Sharing our two articles from @alzheimerssoc DTC APOE research and Protein misfolding with @TauRx @SussexUni @SussexNeuro @BrainEnergyLab @OGSteele healthawareness.co.uk/neurol…
Lovely paper from generated from a chance meeting at a conference! Well done Guna and @mahmoudbukar pubmed.ncbi.nlm.nih.gov/3327…
SerpellLab retweeted
Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuroscience frontiersin.org/articles/10.…
Frontiers | MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments | Frontiers in Molecular Neuroscience frontiersin.org/articles/10.…
SerpellLab retweeted
I’m looking for a Phd student to join my lab at @SussexNeuro @SussexLifeSci in September 2021, to study the modulation of early visual processing by behaviour and neuromodulation.
👉bit.ly/3lcduHn
But there is more...
SerpellLab retweeted
👏Highlighted in our new issue: #AmyloidBeta 1-42 internalisation and toxicity are influenced by conformation and assembly state rather than size. Study by @KarenEMarshall @Serpell1 & colleagues →bit.ly/38vXYCO #neurodegeneration #Alzheimers @Serpelllab @SussexNeuro
SerpellLab retweeted
Read @cathnaledi ‘s latest blog all about our #mrc funded research project investigating blood flow and #Alzheimers ! 🧠
Do bad blood vessels trigger #Dementia? @BrainEnergyLab is trying to understand how changes in blood vessels in the brain are linked to the onset of #Alzheimer’s disease. Find out more about their research in our latest blog: ow.ly/IhjS50Cgldc
We loved working with you!
This work, during my undergrad @SussexUni in the wonderful @SerpellLab, was what made me pursue a career in research! I contributed a very small amount to this paper but it was a very significant part of my baby science career 🤩 #neuroscience
Latest work from Devkee Vadukul with @KarenEMarshall and @mahmoudbukar Plus 2 ug project students!! @neuroblonde and Astrid!. Internalisation and toxicity of amyloid‐β 1‐42 are influenced by its conformation and assembly state. febs.onlinelibrary.wiley.com…
SerpellLab retweeted
We're excited to announce this year's virtual Carols at Christmas concert (Thursday 17 Dec) will include a performance by musician Paul Harvey!
We would love for you to join us! Book your free ticket today: bit.ly/3dIvFBu (with thanks to @mrnickharvey for the video).
SerpellLab retweeted
Our latest paper investigating the structural polymorphism of #amyloid fibrils is now published with @SpringerNature in @CommsChem :) we use AFM to reconstruct and quantify amyloid polymorphism: rdcu.be/b64Ar @LDAubrey @LiisaLutter @CJSerpell @psinomore @SerpellLab
SerpellLab retweeted
PostDoc position in Cryo-EM of Neurodegeneration in our group at the EPFL, Lausanne, Switzerland. We offer excellent working conditions with outstanding equipment in a beautiful city at the Lake of Geneva. More info at epfl.ch/labs/lbem/open-posit…
SerpellLab retweeted
Can we distinguish seeding through templated elongation, where the specific conformation encoded by amyloid fibrils is propagated, from a more generic surface-catalysed seeding mechanism? Yes we can, our new manuscript shows how we did it 😊🔬💡: biorxiv.org/cgi/content/shor…
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SerpellLab retweeted
We have two open possitions in the lab. A permanent Senior Lab Research Scientist (a mix of a permanent postdoc and lab manager) and a Postdoc. We investigate how neural circuits function and evolve using a multidisciplinary approach. For more info: prietogodinolab.org/team/joi…
SerpellLab retweeted
Crazy to think I can call myself an author! It's finally out
onlinelibrary.wiley.com/doi/…
Thank you so much to @Eddi34165646 @AndHaze
#tauteam @UKDRI @SchiavoMNPlab
Knockin’ on heaven’s door: Molecular mechanisms of neuronal tau uptake
