Director of the Systems Immunology Lab @NeckerINEM @Univ_Paris @CNRS. Dissecting virus-host interactions and revealing cell circuits controlling innate immunity

Paris, France
Joined August 2019
Sagi Shapira retweeted
@NeckerInem is delighted to welcome Dr. Nicolas Venteclef @VenteclefNicol1, an internationally renowned expert in immunometabolism working on macrophages and type 2 diabetes, as new Group Leader, bringing considerable strength to our fundamental and translational activities.
3
9
1
34
Sagi Shapira retweeted
That we only vaccinated 292,552 Americans today, having been able to hit 800,000 Thursday (7 Jan), speaks to the lack of any 24/7 plan or ability to execute. Emergencies don't take off weekends.
65
389
48
2,541
I’m all for SciComm, but the explosion of discussion on Twitter about virus evolution and viral variants has devolved into a complete shit show, largely because of non-experts with blue checkmarks & large followings tweeting/publishing hyperbolic speculations. Needs to stop!
7
9
1
220
Sagi Shapira retweeted
For anyone who missed this paper, @gorkalasso BarryHonig & @ShapiraLab use protein structure similarity to scan for molecular mimicry between host & viral proteins. Several interesting candidates identified in pox, herpes, paramyxo, and coronaviruses. doi.org/10.1016/j.cels.2020.…
So proud of you. ❤️❤️🇺🇸🇺🇸
7,934
39,557
14,187
413,418
And here it is, your Moment of Zen
2,267
17,435
3,953
132,649
Viruses frequently mimic host proteins (e.g. due to horizontal gene transfer). This paper uses protein structure similarity to scan for mimicry, and points to mimicry as a pervasive strategy employed by viruses. cell.com/cell-systems/fullte…
1
38
2
89
Sagi Shapira retweeted
Global Release: Harvard Medical School Immunology Seminar Series Full schedule: dms.hms.harvard.edu/immunolo… Zoom link: harvard.zoom.us/j/9495334099… Passcode: 840345
3
93
6
227
A combination of clinical and molecular analyses supports an association between disorders of immune complement or coagulation with poor outcome in patients with SARS-CoV-2 infection #COVID19 @nicktatonetti @ShapiraLab @mason_lab @Columbia go.nature.com/31cL72Z
Sagi Shapira retweeted
Uncovering the role of clotting predisposition and the inter-related complement system in patients w/ #COVID19. —The risk of age-related macular degeneration, a complement disorder —Underpinnings of clotting and worse outcomes nature.com/articles/s41591-0…
10
56
8
120