@DKFZ postdoctoral fellowship awardee & @TMO_Heidelberg team member excited about unraveling targetable vulnerabilities in sarcomas | @NKI_nl & @zwartlab alumni
Joined February 2019
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Beyond excited to finally share our new publication in @CD_AACR, in which we show how prostate cancer cells hijack circadian rhythm regulators to sustain proliferative potential upon AR blockade. A true team effort! @zwartlab @NKI_nl @oncodeinstitute
loom.ly/lc-JIL0
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Simon Linder retweeted
@CancerCoreEU brachte vom 6. - 11.10. erneut Nachwuchskräfte und Expert:innen aus der Krebsforschung an der Algarve zur CCE Summer School in Translational Cancer Research zusammen.
Das NCT Heidelberg war dabei stark vertreten.
Hier zum Rückblick nct-heidelberg.de/das-nct/ne…
Simon Linder retweeted
🚀 Excited to share another successful CCE Summer School in Translational Cancer Research! ☀️🥼 A huge thank you to everyone who contributed to making #CCESummSchool24 memorable.
➡️ shorturl.at/G5Wce
Had an amazing time at #CCESumSchool24 in Albufeira, representing @NCT_HD and @DKFZ! A week of inspiring talks, hands-on workshops, and connecting with brilliant scientists from top EU cancer centers.
Thrilled to win the best participant talk prize! Big thanks to @CancerCoreEU!
Simon Linder retweeted
Wrapped up #CCESummSchool24 with fantastic talks on Tumor Microenvironment, Advanced Therapies & Sexual Dimorphism
Congrats to @HandlVerena @MedUniGraz, @MarikaReinius @CRUKCamCentre, @Manon_deGraaf @NKI_nl for Best Posters & @Simon_Linderson @NCT_HD for Best Participant Talk 👏
Simon Linder retweeted
Congratulations to the stellar @DKFZ PostDoc @Simon_Linderson for winning the award for Best Participant Presentation at #CCESumSchool24! 🎉🏆 He gave a talk on how enhancer hijacking events upregulate genes that could serve as targets for novel sarcoma therapies. @CancerCoreEU
Simon Linder retweeted
Exciting findings in #childhoodcancer
#oncofetal reprogramming of postnatal #stemcells and CD52 as a novel therapeutic target in #pediatric #leukemia
New preprint from our lab by
@mp_hartmann
@MaxSchoenung
@dblipka1
biorxiv.org/content/10.1101/…
ALT https://www.biorxiv.org/content/10.1101/2023.10.27.563754v1
Simon Linder retweeted
Ever wondered how transposable elements are used differently across development and towards oncogenesis - We provide insights on their role as regulatory elements across pluripotent, mature and cancer cells, with a focus on prostate cancer: aacrjournals.org/cancerdisco…
Simon Linder retweeted
Please RT: We are hiring informaticians for HEROES-AYA (bit.ly/3ziizaN), a multicenter program within the @XgegenKrebs that aims to understand and target tumor heterogeneity and evolution in adolescents and young adults with #sarcoma.
karriere.klinikum.uni-heidel…
Simon Linder retweeted
So proud of @IsabelMayayo who brilliantly defended her PhD! 🎓 As her co-promoter, alongside @zwartlab, at @NKI_nl, I've witnessed her unwavering determination & exemplary work first-hand. Excited for the brilliance her future holds! #WomenInSTEM #ProudMentor #AcademicChatter
Simon Linder retweeted
1/3 Are you struggling with different Hi-C data analysis and the handling of different input formats for different tools? Have a look at 𝘴𝘯𝘏𝘪𝘊: the new @zwartlab snakemake Hi-C pipeline, now published on @BioinfoAdv!
DOI: doi.org/10.1093/bioadv/vbad0…
academic.oup.com/bioinformat…
Simon Linder retweeted
🧬1/ How do SHRs regulate transcriptional activity, and which components of the SHR-coregulator complex are essential for transcription? Our study, published in @NAR_Open, used a FACS-based CRISPR screen to dissect the GR complex. academic.oup.com/nar/advance… 🧵
Many thanks to Leonie Young, @damirvareslija and @donaldmcdonnell for giving me the opportunity to present my @zwartlab PhD research on acquired prostate cancer vulnerabilities in the Young Investigator Session at the @Endoadapt Dublin Steroid Cancer Conference @RCSI_Irl. 🧬
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Simon Linder retweeted
September issue—
Drug-induced Epigenomic #Plasticity Reprograms #CircadianRhythm Regulation to Drive #ProstateCancer Towards Androgen-Independence, by @Simon_Linderson, @MarlousHoogstr1, @hvdpoel, @BergmanAndries, @zwartlab et al.
bit.ly/3qQxDqW
@NKI_nl @oncodeinstitute
I’m very happy to have received the best poster price at the @EMBO #NuclearReceptors meeting in beautiful Malta, where I presented our latest @zwartlab research. Kudos to @JCarrollLab and all other organizers - it was absolutely amazing. 🧬
Simon Linder retweeted
Excited to share our work on "cistrome-wide association studies" (CWAS) in @NatureGenet. #CWAS identifies #GWAS variants that influence traits and diseases through local effects on the #epigenome. rdcu.be/cU85l
Simon Linder retweeted
In the Spotlight: Why ARNT prostate tumors responding to enzalutamide? By Meng Zhang, Thaidy Moreno-Rodriguez, and @David_A_Quigley.
bit.ly/3Qp16CJ
@UCSFCancer
Thanks @CD_AACR for featuring our @zwartlab study 'in the spotlight' section of the September issue! Great commentary by @David_A_Quigley et al. 🧬
