Gastric carcinogenesis / Stem cells / Transgenic mouse models / Organoid models
VUMC
Joined August 2021
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We are hiring a postdoc to work on patient-derived pre-cancer organoids to examine the susceptibility of pre-cancerous lesions to drug treatment and to optimize possible therapies using Pyrvinium (Phase II trial) to reduce the risk of gastric cancer. lab.vanderbilt.edu/choilab/
Excited to share our new paper led by @AlexisGuenther1 and out in @gastroenterology; SOX9-driven SPEM cell lineage plasticity is a potential therapeutic target that mitigates risk of metaplastic progression to gastric cancer - Gastroenterology gastrojournal.org/article/S0…
#DDW2026, my group will share much of our recent work!
Day 1
Oral Presentation-no. 279
Poster Presentation-Sa1213
Day 3
Oral Presentation-no. 666
Day 4
Oral Presentation-no. 1012
Poster Presentation-Tu1817
Invited Talk-Eunyoung Choi, Sp1199
@VUMChealth
I’m happy to share that I’ve been appointed to a new role as VICC Gastrointestinal Cancer Research Program Fellow at VUMC!
Congratulations to Dr. Alexis Guenther on the successful defense of her PhD dissertation! I am grateful to have had the opportunity to supervise her as my first graduate student! I should get more photos of her, but I can’t wait and am just posting this now! @AlexisGuenther1
CHOI LAB retweeted
Registration is now open for Gastrointestinal Tract XXII
Snowbird Ski Resort | Salt Lake City, UT
August 30-September 3, 2026 #GITractSRC
events.faseb.org/event/72886…
@GoldenringLab @magnesslab
@The_Choi_Lab
@JosephBurclaff
@millsjc67 @BusadaLab
@DelgiornoKathy @AmyEngevik
Excited to share the upcoming FASEB Catalyst Conference, “Tumor Organoid Modeling in Cancer Biology,” in November 2026! We’ll highlight mechanistic cancer biology, lineage plasticity, single‑cell/spatial approaches, and translational organoid research. @dechen_lin @FASEBorg
Great day of bowling and good food with this awesome group! Loved getting to know everyone better! @GoldenringLab @ZachosLab @iKajiLab @tae_hwang
CHOI LAB retweeted
I don't understand how someone can read this and not think that the American biomedical research system is a modern miracle that should be protected at all costs
In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe, rapidly progressing genetic disease... all in an astounding 7 months. Best of all, the infant patient shows apparent benefit. Congratulations to @kiranmusunuru, Rebecca Ahrens-Nicklas, and other team members for this heroic and inspiring effort, which has implications for the hundreds of millions of patients that suffer from thousands of genetic diseases.
drive.google.com/file/d/1Jfk…
Always amazing science and people @DDW1025. So proud to be part of @AmerGastroAssn. 5 presentations from my trainees and my Young Investigator Award. Lots of good things to recap!
A big congratulations to my lab members, Youngwon Cho, a recipient of AGA Fellow Abstract Award, and
@AlexisGuenther1, a recipient of AGA–Radhika Srinivasan Student Abstract Prize! gastro.org/news/introducing-…
CHOI LAB retweeted
Attending #DDW2025? Don’t miss the May 4, 8AM Translational Symposium: Cellular Plasticity in Metaplasia-with @GoldenringLab, @Aiims1742, Stuart McDonald & Juanita Merchant discussing GI lineage progression, evolution, & immune signaling. Honored to co-moderate w/ @The_Choi_Lab
CHOI LAB retweeted
🎉 We’re proud to announce the recipients of our 2025 AGA Recognition Awards! These GI leaders, such as @MichelleKimMD @traceyg_md @LewisRobertsMD @MicrobiomeDoc and @ibbnida, are advancing patient care and driving research innovation. 👏 Read more: ow.ly/HHKU50VxA1P
CHOI LAB retweeted
Calling all students in NIDDK relevant disease research fields! 🔬📊 Ready to explore data management, #FAIR data, rigor and reproducibility, and #datascience? The dkNET Summer of Data program offers training to boost your research skills.
Apply now! ✨ dknet.org/about/Summer-Progr…
CHOI LAB retweeted
The PI of a research lab in academia is the CEO/CSO/CFO combined, and this is on target for that as well. There is no substitute for hustle when you are a PI. The most successful colleagues I see at Anderson are the ones sending me 1AM or 4AM emails. I wish I had their energy!
CHOI LAB retweeted
👋Welcome to our five new governing board members! We're excited to welcome Drs. Richard Peek, Michael Kochman, @KanwalFasiha, @brownbrij76 & Russ Arjal to AGA's leadership. Get to know these distinguished upcoming leaders: ow.ly/ZWG650VgsqK
Check out our new paper in collaboration with the Weaver lab! @AWeaverLab Cortactin facilitates malignant transformation of dysplastic cells in gastric cancer development - CMGH cmghjournal.org/article/S235…
Very excited to welcome @tae_hwang officially!
VUMC to launch Molecular AI initiative to spur precision medicine, transplantation news.vumc.org/2025/01/16/vum…
CHOI LAB retweeted
Excited to start my new role as Founding Director of the Center for Molecular AI, Director of AI Research in Surgical Sciences, & Endowed Chair at @VUMChealth and @VanderbiltU ! Excited to lead AI-driven innovations in biology & medicine to improve patient care. #AI #Innovation #PrecisionMedicine
