Tom Elliot (@TomAshEmElliot) header
Tom Elliot (@TomAshEmElliot) profile picture

Tom Elliot

@TomAshEmElliot

[email protected]

 Manchester, England
Joined December 2018
  • Tweets132
  • Following625
  • Followers337
Tom Elliot retweeted
Sky News (@SkyNews) profile picture
Sky News
@SkyNews19 Nov 2024
Salmonella could be engineered to help fight bowel cancer after research found the bacteria stops the body's own immune cells attacking the disease. 🔗 Read more trib.al/uGiqsQU
'Disease-causing' salmonella could actually help combat bowel cancer, study suggests

'Disease-causing' salmonella could actually help combat bowel cancer, study suggests

Salmonella, which can cause food poisoning, could be engineered to allow a type of white blood cell that protects the body from infection and disease to kill cancer cells.

news.sky.com
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We're hiring! 3year post-doc available in the lab on fungal adaptation to the host. Funded by @wellcometrust and working closely with @BECKS_182 team. Further details in link below, informal enquiries welcome! uk.indeed.com/m/viewjob?jk=e…
Research Fellow - Department of Immunology and Immunotherapy - 104822 - Grade 7 - Birmingham -...

Research Fellow - Department of Immunology and Immunotherapy - 104822 - Grade 7 - Birmingham -...

University of Birmingham

uk.indeed.com
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Very excited to share our latest work, out today in @ScienceMagazine, on the serendipitous finding that vitamin D ☀️ regulates the gut microbiome to promote cancer immunity🦠 science.org/doi/10.1126/scie… 🧵👇 @ReiseSousaLab @TheCrick
Image from Evangelos Giampazolias (@giampazolias)
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Tom Elliot retweeted
Harriet (@harriet_jg) profile picture
Harriet@harriet_jg23 Apr 2024
✨New preprint ✨ So pleased to share my first ever paper from @DrMicroMandroid’s lab at @IMIBirmingham. Here, we used multiplex imaging to show a correlation between H. pylori and invasion of gastric microbiota during gastric cancer development 🧫 doi.org/10.1101/2024.04.22.5…
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Paper publication day! Our latest work online now in @NatureComms on the role of microglia in cryptococcal meningitis. Turns out these cells help the fungus more than us. Short thread of the main findings. nature.com/articles/s41467-0… – at Birmingham, England
Microglia are not protective against cryptococcal meningitis

Microglia are not protective against cryptococcal meningitis

Nature Communications - Cryptococcal meningitis is a life-threatening fungal infection. Here, Mohamed et al find that brain resident microglia do not provide protection against this infection and...

nature.com
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Our review is out now in Essays in Biochemistry. T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures. doi.org/10.1042/EBC20220247 (1/2) @BendingLab @DavidLeckyBio

T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment...

Abstract. Immune checkpoint immunotherapies act to block inhibitory receptors on the surface of T cells and other cells of the immune system. This can increase activation of immune cells and promote...

portlandpress.com
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Here we discuss fundamental mechanisms of negative feedback control of TCR signalling, signatures of repsonse to checkpoint blockade, and how combination therapy strategies may overcome acquired resistance. (2/2)
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Looking forward to present at #BSI22 my poster 466 this afternoon and discuss how combination therapy of anti-Lag3 and anti-PD-L1 can increase TCR signalling duration.
Image from Dr Lozan Sheriff (@LozanSheriff)
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Come check out my poster 432 at #BSI22 today. Talking about regulation of TCR signalling. Also interested in discussing post doc work (graduating in about a year)
Image from Tom Elliot (@TomAshEmElliot)
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Happy birthday to meeeeeeeeeee #BSI22
Image from Poppy Nathan (@poppynathan)
Image from Poppy Nathan (@poppynathan)
Image from Poppy Nathan (@poppynathan)
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💥 A new tool to assess rapid changes in TCR & BCR signalling dynamics #InVivo @TomAshEmElliot & colleagues relay a new transgenic reporter of antigen receptor signalling that expresses Fluorescent Timer protein under the regulation of Nur77 👉bit.ly/3gCvX2U 1/
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Glad to see this out! Thanks for support of @BendingLab and co-authors. In lymphocytes, expression of Nr4a family genes is controlled by antigen receptor signalling - making them great biomarkers of antigen detection. 1/
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Differences in sensitivity between the two systems could well be due to much higher number of Nr4a1 transcripts over Nr4a3 in activated T cells. Please reach out to @BendingLab if you are interested in using Tempo mice! 12/
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CC @MaslowskiLab @LozanSheriff @DavidLeckyBio @GillianMackie_ @LisaScarfe2 @SophieRouvray Thanks for work on this project!
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