@UCDavisIPN

Our mission is to advance our understanding of the basic neurobiology of psychedelics and translate this knowledge into safe and effective therapeutics

 UC Davis
neurotherapeutics.ucdavis.edu/
Joined February 2023
  • Tweets103
  • Following50
  • Followers503
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The UC Davis Institute for Psychedelics and Neurotherapeutics is making the move to BlueSky where we'll continue to share our latest research, events, and more. Follow us now @ucdavisipn.bsky.social. bsky.app/profile/ucdavisipn.…
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Check out this IPN research featured on @VICE: "Psychedelics Minus the Trip: Powerful Anxiety Relief," vice.com/en/article/psychede… @UCDavisCNS @UCDLandS @UCDavisMed #psychedelics #mentalhealth

Psychedelics (Minus the Trip) Could Provide Powerful Anxiety Relief

Separating the anti-anxiety effects from the hallucinogenic effects of psychedelic drugs could be a game-changer for anxiety relief.

vice.com
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Our Fall 2024 newsletter is live! Get the inside scoop on cutting-edge research, staff spotlights, and general updates from the #UCDavisIPN. neurotherapeutics.ucdavis.ed… #psychedelics #neurotherapeutics

Newsletter Fall 2024

neurotherapeutics.ucdavis.edu
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Exciting new research in @ScienceMagazine from the labs of IPN researchers @tinakim_neuro @DEOlsonLab reveals that the neural circuitry mediating the anti-anxiety and hallucinogenic effects of #psychedelics are distinct. @UCDavisCNS @UCDLandS @UCDavisMed science.org/doi/10.1126/scie…

Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states

Psychedelics hold promise as alternate treatments for neuropsychiatric disorders. However, the neural mechanisms by which they drive adaptive behavioral effects remain unclear. We isolated the...

science.org
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Institute for Psychedelics and Neurotherapeutics retweeted
UC Davis Department of Chemistry@UCDChem3 Oct 2024
Exciting news! We've launched a crowdfunding campaign for a new art installation in the Chemistry Building! 🎨 Help us raise $5,000 for the amazing artists! Every contribution and share counts. Let’s create something extraordinary! 🙌💙 Join us: shorturl.at/jL8rb
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The FDA has made the decision to reject Lykos Therapeutics' MDMA-Assisted Therapy for hashtag#PTSD at this time. Read more here: lnkd.in/eQ_PszYC

LinkedIn

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lnkd.in
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While we desperately need new treatments for #PTSD, we believe that this is an opportunity for the field to ensure studies are conducted with sufficient rigor to establish safety and efficacy for novel treatments. The future is still bright for this promising class of compounds.
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IPN faculty affiliate @tinakim_neuro and team just published in @naturemethods about a protein-based tool expected to aid in identifying how #psychedelics impact brain disorders by tagging neurons activated by psychedelics. nature.com/articles/s41592-0…

Rapid, biochemical tagging of cellular activity history in vivo

Nature Methods - CaST is a Ca2+-activated version of split-TurboID. The tool allows labeling active neurons quickly, simply by administration of exogenous biotin, thus enabling the study of...

nature.com
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Still curious about the implications of the FDA advisory committee's review of #MDMA as a treatment for #PTSD? Check out this @JAMA article for more insight. jamanetwork.com/journals/jam…

Psychedelic Therapy Scrutinized by FDA Advisory Committee

This Viewpoint analyzes the Psychopharmacologic Drugs Advisory Committee’s decisions regarding 3,4-methylenedioxymethamphetamine–assisted therapy and what they mean for psychedelic research.

jamanetwork.com
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At the IPN, we're eagerly awaiting the outcome of the FDA's August 11th decision. This is a pivotal moment to refine the field's research and ensure scientific rigor.
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The IPN is hiring a Director of Pharmacology. Join our team and play a key role in advancing cutting-edge research and innovative treatments in mental health. Apply now and help shape the future of psychedelic research! Learn more and #applynow: recruit.ucdavis.edu/JPF06614
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A new study published in @Nature reveals how #psilocybin, the active compound in magic mushrooms, can profoundly impact the human brain. Check out the full study! nature.com/articles/s41586-0… #Psychedelics #MentalHealth #NeuroResearch #Psilocybin #BrainHealth

Psilocybin desynchronizes the human brain

Nature - Healthy adults were tracked before, during and after high doses of psilocybin and methylphenidate to assess how psychedelics can change human brain networks, and psilocybin was found to...

nature.com
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The closure of the 1st UK #psychedelic-assisted therapy clinic underscores the need for developing low-cost compounds that can be safely used at home. Read more in this @BBC article: bbc.in/3WkqS11 Follow @UCDavisIPN to learn more about psychedelic-inspired compounds.

What happened to UK's first ketamine-assisted clinic?

The first ketamine-assisted clinic was a pioneering treatment centre for depression and anxiety.

bbc.com
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The newest research from IPN Director @DEOlsonLab and team suggests that tropane analogs can promote #neuroplasticity with fewer side effects than compounds like scopolamine. Read more here: pubs.acs.org/doi/10.1021/acs…

Identification of Psychoplastogenic Tropanes Lacking Muscarinic Activity

Abstract. Tropane-containing small molecules like scopolamine are a promising class of psychoplastogens. However, their potent antagonism of all muscarinic

pubs.acs.org
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Check out the latest IPN paper in J. Med. Chem. on the development of psychoplastogenic DYRK1A inhibitors with potential for treating Alzheimer's disease especially early-onset Alzheimer's disease associated with Down Syndrome pubs.acs.org/doi/10.1021/acs….

Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer’s Disease

Abstract. Tauopathy, neuronal atrophy, and psychological impairments are hallmarks of neurodegenerative diseases, such as Alzheimer’s disease, that current

pubs.acs.org
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@UCDavisIPN Director @DEOlsonLab talks about psychedelics and nonhallucinogenic psychoplastogens on the @UChicago's Big Brains podcast news.uchicago.edu/psychedeli…

Psychedelics without the hallucinations: A new mental health treatment? with David E. Olson

Scientist examines how non-hallucinogenic drugs could be used to treat depression, addiction and anxiety

news.uchicago.edu
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IPN director @DEOlsonLab was interviewed for this PNAS news feature on the mechanisms of psychedelics pnas.org/doi/10.1073/pnas.23…

If psychedelics heal, how do they do it? | PNAS

If psychedelics heal, how do they do it?

pnas.org
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Institute for Psychedelics and Neurotherapeutics retweeted
UC Davis Letters and Science@UCDLandS27 Dec 2023
Want a preview of what you'll find in @UCDavisIPN’s first newsletter? Check out “A View Inside: How #Psychedelics Promote Neuroplasticity” and scroll down to sign up for the newsletter here: lettersandscience.ucdavis.ed… #health #neurotherapeutics #chemistry #brainhealth
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From #marijuana legalization to the groundbreaking potential of #psychedelics in #psychiatry— @johnalangray and a wave of researchers are reshaping #psychiatric treatments. A paradigm shift in how we approach mental health may just be on the horizon. cleveland.com/news/2023/11/a…

As Americans accept marijuana, use of LSD and other psychedelic drugs as medicine could also grow

Could wider acceptance of marijuana be leading to more open minds on research for the medical use of LSD?

cleveland.com
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Within #psychedelic science, the debate lingers: Is it mind-blowing experiences or powerful #molecules that spur change? Join @TTBOOK to hear David E. Olson's take. Also available on @Spotify! youtu.be/JunhDmkrM88?si=OzEE…
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