Megan Orzalli (@VirulentMind) profile picture

Assistant Professor. @umass_id @UMassChanPII. Virologist. Lover of apocalyptic literature..not apocalyptic real life.

Boston, MA
Joined January 2011
Orzalli Lab: Day 1. #NewPI
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UMass Chan Medical School seeks the next generation of scientific leaders! Join our research community as a UMass Chan Early Independence Fellow. Get 3-5 years of support. Apply by Dec 1: academicjobsonline.org/ajo/j… @UMassChan @RTI_UMassChan
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SARM - an enzymatic TIR protein. Perhaps the most ancient immune regulator in the Tree of Life and the origins of innate immunity itself. But, is it an immune sensor in animals?
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Our August issue is out! hubs.la/Q02JTSw30. The cover shows HSV-1 infection inhibiting ASC speck formation in an A549 cell line. ASC-GFP is in green, ICP0 from HSV-1 is in red, & cell nuclei are in blue. From @JustKOS1 @VirulentMind et al. hubs.la/Q02JTy5C0
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Congratulations to Orzalli Lab MD/PhD student Jenny Powers on her outstanding F30 score! If paylines stay the same in FY25 (fingers crossed) her grant will likely be funded! @UMassChanPII
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The Orzalli lab’s first paper is out today @JExpMed! See the excellent tutorial from first author @JustKOS1 below.
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Honored to have been selected for this award. It has been a true joy mentoring the students in my lab as they pursue their PhD studies!
Congratulations to members of the Department of Medicine who were honored at yesterday’s @umasschan Educational Recognition Awards! #advancingtogether #advancingeducationtogether @RPWLab @VirulentMind @MoormsLab
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Congratulations to Jafira and our other IITP trainees!
We are thrilled to announce the 2023-24 Innate Immunity Training Program trainees! Learn more about this talented group of students here: umassmed.edu/pii/education-a… @umass_medicine @SilvermanNeal
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Accurate
Trainee: Do you have a minute? PI: I actually have to run to a meeting now. Trainee: Oh okay. I just finished graphing these data and wanted to show you, but that can wait until- PI:
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Hanging out with the lab at a WooSox game!
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On my way to #IHW2023...but likely going to get stuck in SLC tonight after a 3 hr delay on the tarmac in BOS. Hopefully won't miss too much of the Satellite sessions tomorrow.
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Love coming into the lab and seeing so many plaque assays!
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Thank you to the @IcahnMountSinai Department of Microbiology for hosting me today for a visit/seminar. Had a great time sharing our work and getting to talk science with the faculty and trainees!
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Congratulations, Andrea!!!! @ReboldiLab
Congratulations to the 2023 Investigators in the Pathogenesis of Infectious Disease @Mari_Byndloss @yiweichang @UTSWedu @HarrisTryonLab @MaayanLevy_Lab @DrShrutiNaik @ReboldiLab @TuftsMedSchool @TuftsUniversity @YanBiofilmLab #bwfpath
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On my way to DC for #AAI2023. Looking forward to sharing our work on inflammasomes in cutaneous antiviral defense tomorrow during Major Symposium B. Come say hi!
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Congratulations to Orzalli lab graduate students Jenny and Jafira for passing their Qualifying Exams! Excited to see where their projects take them over the next couple of years.
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Taking a break on the last day of #KSinnateimmune23 to get some runs in @Snowbird!
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Love this #notthecover from @RPWLab MD/PhD student @tse_elegans! The study it depicts is pretty fabulous as well.
#NottheCover, but still so awesome. Co-first author and graphic artist @tse_elegans created a image highlighting our @ImmunityCP paper (cell.com/immunity/fulltext/S…) (1/3)
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