Neurodegeneration Pathobiology Lab studying TDP-43, on a mission to cure #MND #ALS & #FTD. Led (and most tweets) by @adamkeithwalker. @QldBrainInst, @UQ_News.
Beautiful Brisbane, Australia
Joined March 2017
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Walker Neuro Lab retweeted
The @dehorterlab is excited to share a new study demonstrating a causal link between #immune activation, #alphasynuclein and #Parkinson onset.
This work establishes the first immune-induced model to investigate the prodromal phase of idiopathic #Parkinson.
@QldBrainInst @JCSMR
Alpha Synuclein Induced Immune Response Triggers Parkinson's Disease Like Symptoms biorxiv.org/cgi/content/shor… #biorxiv_neursci
Walker Neuro Lab retweeted
Today would have been Justin's 50th birthday, but as many of you know, Justin passed away last year after a long battle with MND
This weekend the Yerbury lab are taking part in the walk to defeat MND to raise vital funds to support those living with MND ⬇️
walktodefeatmnd.org.au/fundr…
Walker Neuro Lab retweeted
Excellent piece on frontotemporal dementia by @AmyBrodtmann.
Watch Dementia Australia Honorary Medical Advisor Prof Amy Brodtmann MBBS, FRACP, PhD in an on-demand webinar about frontotemporal dementia, discussing the symptoms, strategies, and support available for those impacted by FTD.
Watch now at youtu.be/sD0XpAJ1s0o?si=HA7b…
Walker Neuro Lab retweeted
SAVE THE DATE!
We will be holding the 3rd Australian and New Zealand MND Research Symposium in Melbourne on Tuesday 27th and Wednesday 28th of August.
An MND Connect session will also run on the Wednesday.
Further information to come as we progress with the event.
Walker Neuro Lab retweeted
Trikafta — a triple small molecule combo therapy — can be considered functionally curative, though variant specific top-ups are still in play.
More of this please!
Walker Neuro Lab retweeted
World-renowned scientist Dr. Virginia Man-Yee Lee at @PennMedicine has made groundbreaking contributions to our understanding of tau, earning her the 2024 #RainwaterPrize for Outstanding Innovation in Neurodegenerative Research, to be awarded at #Tau2024. rainwatercharitablefoundatio…
Walker Neuro Lab retweeted
"We found several proteins that were driving disease forward and making it worse... we also found proteins that are increased early in disease and are protective."
@QldBrainInst researcher @Rebecca_SanGlia explains how her protein map could offer therapeutic pathways for #MND.
Walker Neuro Lab retweeted
Congratulations to @elise_kellett, who received the Joan Lawrence Endowment Prize for High Achieving Women in Neuroscience. 💜
Elise is currently doing her #PhD in the @WalkerNeuroLab at the @QldBrainInst, researching potential therapeutic interventions in Motor Neuron Disease.
Walker Neuro Lab retweeted
@TrendsNeuro 'Spotlight' by Matisse Jacobs, Rebecca San Gil & Adam Walker @WalkerNeuroLab
sciencedirect.com/science/ar…
discussing Guo et al. 2023 ‘Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies’
nature.com/articles/s41422-0…
Walker Neuro Lab retweeted
Want to deliver gene therapies broadly, but activate them only in diseased neurons?
TDP-REG "hacks" TDP cryptic mis-splicing to drive expression only WHEN and WHERE needed! Less toxicity, wider therapeutic window, new options for sporadic ALS therapies.
biorxiv.org/content/10.1101/…
Walker Neuro Lab retweeted
Join us on 24 October at 12pm AEDT to hear about how patient registries are helping to accelerate clinical discoveries in MND research.
Register at: fightmnd.org.au/fightmnd-sci…
Walker Neuro Lab retweeted
Super proud of @JulieNecNeuro for the long journey and the massive amount of work that went into this paper. You will be missed!
Our paper is (finally) officially published! Check out our work showing that acetylation-mimic TDP-43 impairs RNA regulation, alters protein localization and solubility, and induces behavioral deficits in aging mice. doi.org/10.7554/eLife.85921.… (1/2)
Walker Neuro Lab retweeted
I'll be sharing our latest results tomorrow as part of the @FightMND Scientific Seminar series. Register using the link: fightmnd.org.au/fightmnd-sci…
Join us on September 26 to hear from our inaugural FightMND Early Career Research Fellow Dr @Rebecca_SanGlia, from the @UQ_News on the topic of protein signatures of TDP-43 proteinopathies in the brain.
For more information or to register visit fightmnd.org.au/fightmnd-sci…
Walker Neuro Lab retweeted
Cryptic RNAs in Alzheimer’s brains with TDP-43 pathology!
New work from @PrudencioLab and wonderful colleagues at Mayo Clinic! Shout out to Virginia Estades Ayuso, her first author publication!
molecularneurodegeneration.b…
Walker Neuro Lab retweeted
We are recruiting a #postdoc who wants to use biochemical approaches to understand how disease happens in #ALS #MND #FTD #dementia apply via the link below. @TargetALS_fdn @alzheimerssoc @ARUKscientist @EuansCentre @MNDScotland @mndassoc . Please retweet.
dundee.t1cloud.com/T1Default…
Walker Neuro Lab retweeted
Dr Odette Leiter and Dr Tara Walker's #research has discovered that platelets, the tiny blood cells critical for blood clotting, secrete a protein that rejuvenates #neurons in aged mice in a similar way to physical #exercise.
Read more:
🔗 bit.ly/3P0anUe
Walker Neuro Lab retweeted
@VAInstitute is hiring faculty in the Department of Neurodegenerative Disease! Come join us in this highly-collaborative institute with excellent support!
nature.com/naturecareers/job… 🧠🧪
Walker Neuro Lab retweeted
QBI's Dr Matilde Balbi and her team study the brain’s recovery from stroke. They aim to identify intrinsic neuroprotective mechanisms and harness them to improve stroke treatments.
Listen now:
🔗bit.ly/3YgJNt3
#podcast #brain #stroke #strokerecovery #strokeweek2023
Walker Neuro Lab retweeted
Postdoc position in molecular mechanisms of neurodegeneration!
Experience with one of the following is a plus: Biophysics, biochemistry, proteomics, RNA biology or neuropathology.
More details and link to apply can be found here 👇
stellenboerse.uni-mainz.de/H…
Walker Neuro Lab retweeted
Our new study of spatial and single-nucleus transcriptomics in Alzheimer's Disease is now on bioRxiv! Immensely grateful to all who contributed to this project, especially to my amazing co-first author Emily and my mentor Vivek @swaruplab1
biorxiv.org/content/10.1101/…