Jack Nicoludis (@_jackn_) header
Jack Nicoludis (@_jackn_) profile picture

structural biology, computational biophysics, genomics, ML/AI |🏳️‍🌈 (my own posts and opinions)

San Francisco, CA
Joined April 2015
Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)Photo by Jack Nicoludis (@_jackn_)
Also noting that the person biking fell into the travel lane where, if there was a car/truck driving there, they would have been run over and potentially killed. Sandwiching people between two lanes of driving cars/trucks is a dangerous idea, and this bikeway should be replaced. – at San Francisco, CA
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The Valencia center bikeway is causing head-on collisions between people, resulting in serious injuries. Mayor Breed and SFMTA should replace the center bikeway with curbside protected bike lanes or pedestrianization immediately. Please take action now: BetterValencia.com – at San Francisco, CA
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Thanks @SFMTA_Muni. Your design is working as intended.
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What happens to the Valencia Street center cycle track when a vehicle obstructs the driving lane? Exactly what you expect. This wouldn’t happen with curbside protected bike lanes (@BetterValencia), which are better for safety, business, and climate. Please end the “experiment.” – at San Francisco, CA
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SFMTA insists that people on bikes “share the road” with cars on Valencia while SFMTA installs its unprotected center cycle track that’s supposedly “closed.” I followed SFMTA’s guidance; look and see what it got me. The center cycle track is flawed; the rollout is almost worse. – at San Francisco, CA
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SFMTA is proposing a center bikeway for Valencia Street, sandwiching people on bikes between two lanes of driving cars. Valencia should have parking-protected bike lanes along the curb. Support the vision at actionnetwork.org/letters/va… or send an email using tinyurl.com/ValenciaBikeLane… – at San Francisco, CA
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Why is San Francisco afraid of this? – at San Francisco, CA
One of the most successful pedestrian streets in the world, the Strøget in Copenhagen, was filled with cars until a 2 year 1962 pilot project. The opposition argued “no cars means no business,” but the street has been a massive retail success, the city’s busiest shopping street.
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Jack Nicoludis retweeted
Happy to share my new paper (arxiv.org/abs/2210.04893) with @cwcoley that introduces a new equivariant shape-conditioned generative model, SQUID, for generating chemically diverse 3D molecules in poses that fit a target shape. (1/9)
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Jack Nicoludis retweeted
“Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning” Here, structural ensembles are generated using ML, MD, and coevolution. From @DelemotteLab and Drew lab (couldn’t find twitter handle). biorxiv.org/content/10.1101/…
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Jack Nicoludis retweeted
it blows my mind that people can see the skyrocketing housing prices, homelessness, and inequality in California and still be a NIMBY, but I guess it’s a lot easier when you bought a home in Marin for $112K that’s now worth millions
This quoted post is unavailable.
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Jack Nicoludis retweeted
AI is “poised” to transform biology. Here’s how AI succeeded in predicting protein structure. Step 1: Invest >$10B dollars over 40 yrs to create the dataset. Step 2: Spend >>$100M @buildmodels @PDBeurope curating the dataset to ensure highest quality. Step 3. Find the patterns.
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One hot encoding summer ☀️
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Jack Nicoludis retweeted
Sherloc clinical classification challenge of CAGI6: Predict the classification of 122,000 novel coding and non-coding variants encountered across genetic tests conducted by Invitae. @acolavin @rachel_hovde @naomina @invitae #CAGI6 genomeinterpretation.org/cag…
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🚨 #HARVARD ALUMNI 🚨 The Board of Overseers election is open! Vote for @mredshirtshaw, @unatalie, and @DrYvetteE to move #HarvardForward on climate action, racial justice, and inclusive governance today: HarvardForward.org/vote
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Jack Nicoludis retweeted
She deserves the Nobel, but this article is such a missed opportunity and missed understanding of the structural problems with academic labor and precarious employment. Unbelievable that ‘postdoctoral student’ and ‘low level PhD’ are dropped in here. nytimes.com/2021/04/08/healt…
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Jack Nicoludis retweeted
Proud to see the final paper from my PhD out today! We used evolutionary couplings-based models to discover protein interactions with residue-level detail. A collaborative effort with co-first @HadeerElhabashy and PIs @deboramarks @OKohlbacher go.nature.com/3b8bInU
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Jack Nicoludis retweeted
I just nominated the 3 pro-climate @HarvardForward candidates for the Harvard Board of Overseers! They need 700 more alumni signatures in the next 10 days to get on the ballot. Please spread the word! Let's show Harvard that the world is watching! harvardforward.org/sign
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Jack Nicoludis retweeted
While I'm here for fast over fair, I want to get it off my chest that struggling to get my dad a vaccine before his chemo starts, while seeing grad student / postdoc friends who WFH & are among lowest risk get vaccinated through affiliations has been quite frustrating.
Similar struggles as I tried to figure out how my dad, 72, w/T2D, and a cancer dx over Xmas (leading him to move in w/me to get treated @UCSF) could get vaccinated. The SF system let me know he was eligible, and after numerous phone calls the best I could get was "Hang tight".
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Jack Nicoludis retweeted
Among 25,000+ U.S. STEM professionals, those who are LGBTQ were more likely to face career barriers, harassment, and professional devaluation than those who are non-LGBTQ, even when accounting for STEM field and other demographic and job-related factors advances.sciencemag.org/cont…
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