Resistance to tyranny is obedience to God.
WV
Joined May 2021
- Tweets22.4K
- Following523
- Followers497
- Likes17K
Based in WV retweeted
I am extremely grateful for the intensity and toxicity of FinX. Nothing accelerates your learning curve like publishing your thoughts and bets into this environment. I can’t live without this - it’s the most productive addiction I’ve ever had
Based in WV retweeted
Life is all about being magnetic and the best way to start attracting everything you want to you is being attractive to life itself
And life, destiny and the world itself all are attracted to, is active people
Being average in today's world means passive
People wait for something to happen. Wait for the opportunity to show itself. Don’t take risks
"Don't stress"
This is being passive
By this same logic, being active is an above average trait. It's attractive
What does being active mean? Move. Have a purpose you chase. Have enough energy to do so
Are you chasing your dreams?
Being active is what's attractive to life. Having dreams is attractive to life.
Do you want life to love you back? Then ask yourself if you're even attractive to it
Life loves energy, movement, and purpose. And to have energy to do everything else, you need sugar
Sugar is what attracts life. What makes you admire the sun when it shines. What makes your dreams lucid and gives you a reason to jump out of bed
Without sugar the sun shines less. Your dreams can wait. Your bed starts being comfy enough for you to not want to wake up
This is what bioenergetics is all about
Once you achieve enough energy you can sense how you surround yourself in a magnetic field strong enough that things start to happen effortlessly
Very few people know this feeling. What a lot of people DO know, is the feeling of being ignored
Low vibrational. Sad. Invisible. This is because of low energy, and sadly, this is average in today's world
But life loves energy. Destiny loves energy. And they would never be attracted to someone who isn't abundant on it
So do you want to be attractive to destiny itself? Flow effortlessly through life? Do whatever you want?
Have enough energy then
Study bioenergetics
Do you understand?
Based in WV retweeted
you need to be getting better. you need to be everythingmaxxing. you need to be repeating the same boring routines consistently. mad competitive. sleepless nights. stacks of journals and empty redbull cans. delusionally optimistic about the future. life. business. martial arts. walks in nature. more life. training. reading. studying. analysing. recovering. emotionless. obsessed. addicted. detached. you need to max out everything in life. just do it, don't matter how hard it is or how long it's gonna take. stand out in a group of idiots and incels, be rare. you need to be the one of a kind that does it. 1 of 1.
Based in WV retweeted
One of the greatest cheat codes in life is brainwashing yourself into having absolute conviction that you're going to make it to the next level. Believe in your vision so deeply that the possibility of failure stops occupying your mind. Reinforce that belief every single day until it becomes part of your identity. You'll begin noticing opportunities you previously overlooked, attracting people who align with your ambitions, and taking actions you would have once considered impossible. You are capable of going far beyond the limits you've been conditioned to accept.
Based in WV retweeted
>be comp biologist in 2005
>chimp genome just dropped
>everyone comparing genes, looking for protein differences
>nah, i have a better idea
>find DNA that mouse, rat, and chimp all agree on
>stuff that hasn't changed in 300 million years
>*ultraconserved*
>then check if it suddenly breaks in humans anyway
>run the scan
>49 regions light up
>only 2 of them code for proteins
>mfw the most human parts of the genome aren't even protein genes
>top hit: 118 bases
>chicken vs chimp: 2 changes in 310 million years
>chimp vs human: 18 changes in ~6 million
>name it HAR1
>human accelerated region 1
>cyberpunk name af
>"what does it do?"
>"we'll find out later"
>be wet lab biologist down the hall
>handed a 118-base mystery
>colleague in Brussels is staining embryonic brain tissue
>mail him a probe, "try this"
>months pass
>email arrives
>it lights up in Cajal-Retzius neurons
>7 to 9 weeks gestation, right when the cortex is building its layers
>it's an RNA gene, folds into a new shape in humans
>10 of the 18 changes keep the fold intact
>evolution was being careful
>still can't say what it actually does
>be enhancer lab in 2008
>run your own human accelerated scan
>top hit: HACNS1, another HAR
>stick human version into a mouse embryo with a blue dye reporter
>blue in the paw
>specifically where the thumb and wrist will form
>chimp version barely does it
>swap 13 human mutations into the chimp version
>now it does it
>we may have found part of the genetic story of the human hand
>still not sure of the general human accelerated function though
>be population geneticist
>see everyone celebrating "positive selection"
>notice the mutations are suspiciously biased toward G and C
>gc_biased_gene_conversion.jpg
>recombination can fake a selection signal for free
>build a model to separate them
>somehow the HARs survive the cut
>about a fifth of them are probably just gene conversion
>be the guy who brings this up at every conference
>nobody likes this guy
>but this guy is right
>be autism geneticist in 2016
>if these regions made the human brain
>breaking them should break something human
>check families where parents are related
>find HAR mutations disrupting both copies
>up to 5% of autism cases in those families
>some reviewers: "most of those CNVs hit genes too"
>shrug
>be machine learning guy, 2023
>train a model to read enhancers
>score every human-chimp difference in ~2,600 HARs
>expect all mutations to push the same direction
>43% of HARs have mutations fighting each other
>one turns the enhancer up, the next turns it down
>evolution overshot and corrected
>let's keep pushing
>huh, human DNA folds differently in the nucleus than chimp DNA
>structural rearrangements over a million years ago
>suddenly old enhancers are next to new genes
>"enhancer hijacking"
>post it, feels good, finally solved
>be yale lab, 2025
>map what 1,590 HARs actually touch, human and chimp side by side
>nearly 3,000 targets
>almost all shared between species
>no hijacking, just retuning old genes
>say the other guys were wrong
>post it, this is *not*solved
>be 2025
>we have CRISPR, organoids, and humanized mice
>put human HARs in chimp neurons
>they grow more branches
>put human HARE5 in mice
>more neurons, bigger cortex
>delete HAR123
>mice get worse at unlearning things
>finally testing them one at a time
>~3,000 to go
>be present day, present time
>telomere-to-telomere genomes for every great ape
>find whole new rapidly evolved regions that weren't even in the old reference
>call them HAQERs
>mfw more HARs
>the list keeps growing
>these things keep popping in every genome scan
>mfw the only thing accelerating here is our confusion
>mfw we still don't fully know what HAR1 does
>be cell biology postdoc at UCLA, 1986
>job: purify vesicles from rat liver
>ez
>purify the vesicles
>something else in the tube
>weird little barrels, way bigger than a ribosome
>fkisdis
>purify the barrels instead
>mostly protein, tiny bit of RNA
>not related to vesicles at all
>new organelle just dropped?
>lab holds a naming contest
>"vaults" "sure, "great name" "
>write it up, publish
>conclusion section: "function: unknown"
>surely we'll figure it out in a couple years
>reviewers: "are you sure this isn't just a virus"
>prove it isn't a virus
>apply for grants to study it
>first question on every call: "what does it do"
>"we're working on it"
>be early 90s
>vaults hang around the nucleus
>"they must plug the nuclear pores"
>they do not
>be different scientist, Netherlands, 1995
>chasing LRP, mystery protein that shows up in chemo-resistant tumors
>clone it
>~88% identical to rat vault protein
>it was vaults the whole time
>whole cancer field piles on
>a decade of papers on vaults and drug resistance
>nobody ever proves vaults cause it
>back at UCLA
>one of the vault proteins binds telomerase
>"guys what if this is the fountain of youth"
>knock it out in mice
>telomeres fine, aging fine, mice fine
>2002
>knock out the main vault protein
>mice: perfectly healthy
>knock out all three vault proteins
>completely vaultless mice
>mice: basically fine, some subtle immune stuff
>mfw something in every cell since the dawn of eukaryotes does nothing obvious
>"just test it in yeast"
>yeast don't have vaults
>"worms then"
>no vaults
>"fruit flies"
>no vaults
>mfw every easy model organism dropped them
>try making recombinant vaults in insect cells
>expecting to get some loose protein at best
>get fully assembled vaults
>can't find a single free copy of the protein anywhere
>turns out ribosomes 3D-print the barrel straight off the mRNA
>lolwut
>still no function
>be structural biologists
>spend years modeling it as 96 proteins with 8-fold symmetry
>2009 X-ray structure
>it's 78 proteins, 39-fold
>caps still blurry
>2025: caps are closed, 13-fold, tiny hole in the middle
>still no function
>NIH funds vault research for 15 years
>NIH: "so what does it do"
>"...we're working on it"
>NIH stops returning calls
>if we can't figure out what it does, we'll make it do something
>stuff a cancer-fighting chemokine inside the barrel
>inject into mouse lung tumors
>immune cells swarm in, tumors shrink
>2011: "human trials within three years"
>2024: "human trials next year"
>2025 database: preclinical
>start a YouTube channel explaining vaults to anyone who'll listen
>be different scientist, Broad Institute
>want to record what genes a cell turned on over time
>try tethering mRNA to a bacterial protein
>doesn't work
>stumble onto a YouTube channel about some obscure barrel organelle
>engineer vaults to grab mRNA
>RNA half-life goes from ~17 hours to ~132 hours
>publish in Science, 2026
>use it to catch drug-resistance genes in lung cancer cells before the drug even hits
>the vault guy is thrilled
>still nobody knows what vaults are for
>be epigeneticists
>screen the whole genome for methylation set at random in the early embryo
>separately study kids conceived in different seasons in rural Gambia
>both screens independently point at the same gene
>it's the goddam vault RNA gene
>its methylation depends on conditions around conception, locked in for life
>linked to cancer outcomes, blood sugar, cleft palate
>mfw the mystery barrel has a mystery RNA that remembers when you were conceived
>40 years later
>one of the most abundant structures in your cells
>still not in a single textbook cell diagram
>we use it anyway because yolo
>function: unknown
Based in WV retweeted
holy shit physicists have confirmed a THIRD type of magnetism, after over 90 years of thinking there were only two.
it's called altermagnetism, and it could change how computer memory gets built.
inside magnetic materials, electrons behave like tiny magnets pointing in different directions.
until now, we had two main types:
> ferromagnets:
the tiny magnets point the same way.
easy to read, but outside magnetic fields can interfere with them.
> antiferromagnets:
they point in opposite directions and cancel each other out.
much more stable, but really hard to read.
> altermagnets:
they somehow do BOTH.
their tiny magnets cancel each other out,
making them resistant to magnetic interference,
but they can still produce signals that computers could use to read information.
so scientists may have found a way to make computer memory that's both harder to accidentally scramble AND easier to read.
researchers led by SLAC studied manganese telluride, a material we'd been calling an ordinary antiferromagnet for decades.
they fired left and right handed X-rays at it.
the material reacted differently to each one, revealing a hidden magnetic structure that ordinary antiferromagnets shouldn't have.
they first measured it in 2024,
repeated the experiment in 2025 and published the results in Science in October 2026.
the name "altermagnetism" was only proposed in 2022.
we've been studying magnets for centuries and apparently we're still discovering new kinds of magnetism in 2026 😭
Based in WV retweeted
Wow!!!
The Vice President of the United States just did the strangest thing a serving VP can do.
He wrote a public autopsy blaming his own administration's war for a historic defeat.
By the time I read it, it had 38 million views.
If you read it as "venting" then you missed the whole point. But if you read it as positioning and it snaps into focus.
A loyal number two eats a loss like this quietly. You do NOT go out in public and pin the worst night your party has had in years on the signature policy of the president @POTUS you serve.
@JDVance did exactly that, and he gave himself cover doing it, "the president himself said so last night."
He is using Trump's own words as a shield while making Trump's war THE reason the GOP lost the SENATE for six years.
Call that what it is, a man building distance and making sure he cannot be blamed for building it...
Now look at his four reasons, the ones he hangs on the base.
1. End the war.
2. Cost of living.
3. America First.
4. And then, change our relationship to Israel.
Three of those are safe populist lines any Republican can shout.
The fourth is the one that ends careers in this party and this America, and instead of saying it in his own voice, he put it in the mouths of the voters.
That is how you float the most dangerous position in the GOP without owning it. I am only telling you what the base wants.
So the real signal is underneath all of it.
Vance is reading where the Republican coalition is GOING, well ahead of where it is today.
He is planting a flag in the anti-war lane while the war is still on, because if it goes badly through 2027 every I-told-you-so compounds in his favour.
And he is loosening the one tether, Israel, that a post-war base may punish hardest.
He is buying a cheap option on 2028 and letting the party's own anger pay for it.
The order of effects runs outward from there.
1. First he boxes Trump, who cannot disown the war-cost-us line without contradicting his own mouth.
2. Second he claims the restraint wing of the party before any rival moves into it.
3. Third, and the region is reading this too, the second most powerful man in Washington just told the world that the American appetite for this war is cracking.
4. Allies and adversaries both price that in.
This is what the opening of a succession looks like.
A weakened principal, a war that split the coalition, and a VP who is first into the crack. None of that was a slip. He drew a map for his own career.
I fear for his safety.
𝗦𝗜𝗚𝗡𝗔𝗟, 𝗡𝗢𝗧 𝗡𝗢𝗜𝗦𝗘!
Based in WV retweeted
Photo 1: circa 2009, ~145 lbs
Photo 2: last week, ~140 lbs
In the ~17 years between these photos I spent most of my time between 130-145 lbs trying to make the scale go down. Eating less, exercising more, doing all the cardio. But sometimes (many times, especially for women) the answer isn’t losing more weight. It’s building more muscle. At some point u will likely need to worry less about the number on the scale & more about the number on the barbell.
I think the longer u do this & the more advanced u get, ur relationship with the scale changes & u no longer see the scale number as a goal. I’ve looked like a sack of potatoes at 140 lbs and now I have faint abs & vascularity at 140 lbs. so in hindsight It makes me mad that I spent so many years just trying to make the number on the scale go down. It wasn’t the answer. Now I see the scale as just an accountability tool, not a goal driver.
Based in WV retweeted
Just FYI as someone who works in consumer tech and sees a whole lot of conversations online daily: people are starting to snap. Between the price of everything and being surrounded by these foreigners who don't belong here who are somehow better off than our own people who are struggling and the politicians who are enriching themselves and kissing Israel's ass on TV all day people have had enough. It's a pressure cooker out there.
Based in WV retweeted
almond milk production killed 4 billion bees and used hundreds of billions of gallons of water
meanwhile cows enjoy being milked
veganism is a con
