@jpzargs

Senior Scientist, Discovery Biologics @ Merck, previously @ UC Berkeley and Johns Hopkins. He/him 🇵🇭

 Berkeley, CA
scholar.google.com/citations?user=Pp6vfD0AAAAJ&hl=en
Joined May 2009
  • Tweets7.4K
  • Following634
  • Followers205
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Paulo Zaragoza retweeted
Marie Heffern@marieheffern24 Jul 2023
Excited to share the lab's latest #bioinorganic work in @J_A_C_S showing that copper can facilitate complexation of C-peptide and albumin, offering important implications on C-peptide's biological activity and application as a biomarker. pubs.acs.org/doi/full/10.102…

Copper(II) Affects the Biochemical Behavior of Proinsulin C‑peptide by Forming Ternary Complexes...

Abstract. Peptide hormones are essential signaling molecules with therapeutic importance. Identifying regulatory factors that drive their activity gives im

pubs.acs.org
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Honored to be part of this year’s C&EN's Talented 12 class! #CENT12 #FilipinoChemist cen.acs.org/materials/inorga…

Maxx Arguilla

This materials chemist creates atom-thin wires and sheets with exciting electronic and optical properties

cen.acs.org
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Hola, our latest work is now up on PNAS. Mechanical disassembly of nucleosomes using optical tweezers with fluorescence detection (Fleezers). @CesarDiazC, @cccDNA, Robert, Juan Pablo, @Meng3054, Enze, @AndyQuaen, Michael, Ryan, Bibiana, and Carlos. pnas.org/doi/10.1073/pnas.22…

Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disass...

Nucleosome DNA unwrapping and its disassembly into hexasomes and tetrasomes is necessary for genomic access and plays an important role in transcri...

pnas.org
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Paulo Zaragoza retweeted
Victoria Gao@S_H_Gao21 Jul 2022
New paper from Klinman lab! authors.elsevier.com/c/1fS81…
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Temporal and Spatial Resolution of a Protein Quake that Activates Hydrogen Tunneling in Soybean Lipoxygenase biorxiv.org/cgi/content/shor… #biorxiv_biophys
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Paulo Zaragoza retweeted
Goldberg Lab@Goldberg_Lab27 Jan 2022
Congratulations to our incredible PI, Prof Goldberg, for his election to this year’s AAAS Fellows, among the most distinct honors in the scientific community. He is being recognized for contributions in inorganic and bioinorganic chemistry! bit.ly/3o12kZs

Seven Johns Hopkins researchers named AAAS fellows

The American Association for the Advancement of Science recognizes scholars for their contributions to chemistry as well as biological, pharmaceutical, and medical sciences

hub.jhu.edu
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Paulo Zaragoza retweeted
Flood Group@floodgroup_iub12 Jan 2022
In the world of host-guest chemistry, nothing is certain except the taxes of host organization – come learn how we measured it for the first time using molecular origami pubs.acs.org/doi/10.1021/jac…

Revealing the Hidden Costs of Organization in Host–Guest Chemistry Using Chloride-Binding Foldamers...

Abstract. Preorganization is a key concept in supramolecular chemistry. Preorganized receptors enhance binding by minimizing the organization costs associa

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Paulo Zaragoza retweeted
J. Am. Chem. Soc.@J_A_C_S7 Jan 2022
Nonequilibrium Catalytic Supramolecular Assemblies of Melamine- and Imidazole-Based Dynamic Building Blocks @iiserkol #Supramolecular #Melamine #Dynamic #Nonequilibrium pubs.acs.org/doi/10.1021/jac…

Nonequilibrium Catalytic Supramolecular Assemblies of Melamine- and Imidazole-Based Dynamic...

Abstract. The development of synthetic nonequilibrium systems has gathered increasing attention due to their potential to illustrate the dynamic, complex,

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First paper of 2022 out today in @NatureChemistry! Combining single-molecule spectroscopy 🔬 + ultrafast spectroscopy --> new insights into how photosynthetic organisms🦠 capture light w/ high quantum efficiency despite protein fluctuations @ChemistryMIT nature.com/articles/s41557-0…

Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-...

Nature Chemistry - In photosynthesis, photoenergy transfers through chromophore-containing proteins, which exhibit thermal fluctuations that change the positions of the chromophores. Now the...

nature.com
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Want to improve your academic writing? Here are 5 tweets full of excellent writing tips. Because it’s about time I start sharing all the great tweets I bookmark. @AcademicChatter #AcademicTwitter
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Dr. Hannah Schacter@hannah_schacter27 Jul 2021
I've come to learn that my (problematic) writing quirk is (way too frequently) using parentheses to (attempt to) increase clarity, thus ultimately undermining (i.e., destroying) clarity.
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Paulo Zaragoza retweeted
Tonyo Cruz@tonyocruz26 Jul 2021
THIS IS OUR MOMENT: #PHI's first-ever #Olympics gold medalist Hidilyn Diaz salutes the Philippine flag as the national anthem Lupang Hinirang is played for the first time in the Games
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It was harder than I thought to write this, but my piece on my journey from immigrant girl to research scientist/professor is out today in @ScienceMagazine How I learned to embrace my identity as an academic with immigrant working-class roots sciencemag.org/careers/2021/…
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Paulo Zaragoza retweeted
Powers Lab@Powers_Lab23 Jun 2021
In our new @ChemRxiv submission we report the synthesis and nitrene transfer photochemistry of Mn(III) N-haloamide complexes. Low temperature spectroscopy indicates that photolysis of N-iodoamides yields Mn(IV) nitrenoids. Check it out! chemrxiv.org/engage/chemrxiv…

Nitrene Photochemistry of Manganese N-Haloamides | ChemRxiv

Here we report the synthesis and nitrene transfer photochemistry of Mn(III) N-haloamide complexes. Photolysis results in both C–H bond amination and olefinic aziridination products. Low-temperature...

chemrxiv.org
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Paulo Zaragoza retweeted
Jahan Dawlaty@JahanDawlaty27 May 2021
Our recent work on understanding the interplay between electrochemical proton-electron transfer, desolvation, and interfacial electrostatics is just published in @J_A_C_S . The trick was to attach a vibrational probe to the proton donor. pubs.acs.org/doi/full/10.102…

Mechanistic Insights about Electrochemical Proton-Coupled Electron Transfer Derived from a Vibrat...

Abstract. Proton-coupled electron transfer (PCET) is a fundamental step in a wide range of electrochemical processes, including those of interest in energy

pubs.acs.org
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Paulo Zaragoza retweeted
Klinman Lab UCB@klinmanlab3 May 2021
Gorgeous day in Sebastopol to celebrate the lab’s first in-person gathering after more than a year, Judith’s 80th, and Wen’s going away party as she leaves for UK for her new job— We will miss you Wen!!
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Paulo Zaragoza retweeted
Dan Ibarra@Dan_E_Ibarra18 Apr 2021
Replying to @UC_PPFP
@UC_PPFP retreat this weekend - really wonderful STEM discussion session! Great to see friendly faces incl. @AlyssaJGriffin @DrYemiAdebiyi @TadesseberhanuA @jpzargs @JesseLPeltier and many thanks to @SarahAarons @ScottMoura and others for moderating the talks and sessions!
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Please join us on Tuesday, April 13 to recognize the achievements of our colleagues, Kenneth D. Karlin @KarlinLab @JohnsHopkins, Katherine Franz @FranzLabDuke @DukeChemistry, David Mitzi @DukeU and Paul J. Chirik @pchirik @PrincetonChem
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Our latest collaborative work on allosteric communication in Class A β-lactamases is out in @eLife elifesciences.org/articles/6…
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