Development, heredity and structure. Postdoc, https://xitter.cf/t.co/h3PPClRkQN Columbia University PhD, @wbderry lab University of Toronto
Joined September 2011
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Why are so many inherited traits not explained by genome sequence variation? In my PhD work with @wbderry we describe a new mechanism of inheritance in animals that may account for this ‘missing heritability' 🧵nature.com/articles/s41556-0…
Matthew Eroglu retweeted
We are pleased to congratulate Matthew Eroglu of @Columbia on joining the 2025 cohort of #LeonLevyScholars in partnership with the Leon Levy Foundation. 👏
Learn more about Matthew & meet each of the Scholars in our latest press release.
Read more: bit.nyas.org/3Yoa6Pf
Matthew Eroglu retweeted
Congratulations to all our @Columbia scientists recognized with @NYASciences 2025 Leon Levy Scholarships in Neuroscience: @matt_eroglu, @YukiHaba_, @sreejan_kumar, @YutaMabuchi and Keshav Suresh. 👏 👏👏
Congratulations to the 2025 #LeonLevyScholars!🎉
Announcing the 2025 #LeonLevyScholars, in partnership with the Leon Levy Foundation. Recipients participate in a multi-year postdoctoral program to advance their careers.
Read more about the Scholars: bit.nyas.org/3Yoa6Pf
Matthew Eroglu retweeted
Congratulations to the 2025 #LeonLevyScholars!🎉
Announcing the 2025 #LeonLevyScholars, in partnership with the Leon Levy Foundation. Recipients participate in a multi-year postdoctoral program to advance their careers.
Read more about the Scholars: bit.nyas.org/3Yoa6Pf
Very grateful to the @NYASciences for supporting me with the Leon Levy fellowship for my postdoctoral work @Columbia
Congratulations to the 2025 #LeonLevyScholars!🎉
Announcing the 2025 #LeonLevyScholars, in partnership with the Leon Levy Foundation. Recipients participate in a multi-year postdoctoral program to advance their careers.
Read more about the Scholars: bit.nyas.org/3Yoa6Pf
Small but significant results that led to our amyloid inheritance study
“Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans vulval development”
micropublication.org/journal…
Matthew Eroglu retweeted
Gut epithelium modifies enteric behaviors during nutritional adversity via distinct peptidergic signaling axes
biorxiv.org/content/10.1101/…
Matthew Eroglu retweeted
"Leaving sticky notes for the children" - Here's a new "Dispatch" @EthanEwe and I wrote in @CurrentBiology about the super cool discovery that @matt_eroglu and Brent Derry had about transgenerational amyloids! (published recently in @NatureCellBio)
authors.elsevier.com/a/1kCED…
Matthew Eroglu retweeted
MoGen researchers at @UofT found that amyloids—proteins tied to diseases like #Alzheimers—can influence heritable traits in C. elegans w/o DNA changes. Published in Nature Cell Biology.
Study led by @wbderry and @matt_eroglu
Read👉 uoft.me/HeritableAmyloids
#Epigenetics #DNA
Matthew Eroglu retweeted
Our neurotransmitter atlas is officially published! This final version includes a lot of extra data (incl. in suppl. files) that weren't in the earlier versions, but I think they could be useful—feel free to check them out!
#neurotransmitter #celegans
elifesciences.org/articles/9…
Delighted that our image was selected as cover for the October issue of @NatureCellBio
👋Our October issue's out!
Cover: Heritable #Amyloids
👉🏻Comment on #EmbryoModels
👉🏼Review: #mitophagy #pink1 #neuroprotection
🔬on: #gastruloids #mechanobiology #Golgi #polycomb #epigenetics #HSF1 #antitumor #Pbodies #cancer & more!
nature.com/ncb/volumes/26/is…
Matthew Eroglu retweeted
👋Our October issue's out!
Cover: Heritable #Amyloids
👉🏻Comment on #EmbryoModels
👉🏼Review: #mitophagy #pink1 #neuroprotection
🔬on: #gastruloids #mechanobiology #Golgi #polycomb #epigenetics #HSF1 #antitumor #Pbodies #cancer & more!
nature.com/ncb/volumes/26/is…
Matthew Eroglu retweeted
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Matthew Eroglu retweeted
Noncanonical inheritance of phenotypic information by protein amyloids: nature.com/articles/s41556-0…
Matthew Eroglu retweeted
💫NEW: @wbderry, @matt_eroglu & co describe protein amyloid structures that are stably inherited across generations and transmit #EpigeneticMemory in C. elegans. MSTR protein loss results in #transgenerational feminization through ectopic GLD-1 expression.
nature.com/articles/s41556-0…
Matthew Eroglu retweeted
Not DNA
Not RNA
Not even epigenetic marks
Inherited amyloid proteins
nature.com/articles/s41556-0…
Matthew Eroglu retweeted
Why are so many inherited traits not explained by genome sequence variation? In my PhD work with @wbderry we describe a new mechanism of inheritance in animals that may account for this ‘missing heritability' 🧵nature.com/articles/s41556-0…
Matthew Eroglu retweeted
Excited to share that I’ve been awarded a fellowship from the American Parkinson Disease Association (APDA)! Huge thanks to APDA for the generous support and to my mentor, Dr. Lorenz Studer, for his guidance! @APDAParkinsons @studerl @MSKCancerCenter
APDA is excited to announce the inspiring researchers and exciting projects being funded for the 2024-2025 year! With $2.6 Million in new funding an increase of over 30 percent from the year before, find out more on our website and see the full list:
apda.link/MakingHopePossibil…
Matthew Eroglu retweeted
😮😮🤯
"...heritable amyloids across generations, which enables proper germ cell sex differentiation. We propose that inheritance of a proteinaceous epigenetic memory coordinates developmental timing and patterning with the environment to confer adaptive fitness." – at Phoenix, AZ
Not DNA
Not RNA
Not even epigenetic marks
Inherited amyloid proteins
nature.com/articles/s41556-0…
