Dan Patrick retweeted
Restricting carbs after a glycogen-depleting workout nearly doubled peak fat oxidation during a workout the next day.
It also shifted Fatmax from 41% to 56% of VO2 peak.
But it came with a cost…
a ~7% drop in maximal power output at a higher perceived effort.
And low-glycogen training didn’t enhance markers of mitochondrial efficiency or energy production.
Dan Patrick retweeted
The biggest cheat code for your brain is telling yourself everything will always work out in your favor.
Dan Patrick retweeted
Regular exercise improves mental health (anxiety, depression, cognition). Improved cerebral oxygenation and mitochondrial function may be key mechanisms. Therapeutic mild hypoxia combined with exercise could enhance benefits, but evidence is limited.
sciencedirect.com/science/ar…
Dan Patrick retweeted
I can’t stop thinking about this
my spidey senses are telling me the labs are, as we speak, using unguardrailed versions of their unreleased models to systematically reverse-engineer ALL of the internet’s software, apps, and games, then feeding the reconstructed source code straight into their training pipelines while simultaneously building guardrails to ladder-pull the rest of us
Dan Patrick retweeted
“Write to please just one person. If you open a window and make love to the world, so to speak, your story will get pneumonia.”
— Kurt Vonnegut
Dan Patrick retweeted
You can legally load your whole family into a single-engine plane and fly them over the ocean with about 40 hours of flying lessons. That's roughly one work week.
Once you have the license, the FAA asks you to go up with an instructor once every two years. Airline pilots need 1,500 hours just to get hired, and they're back in a simulator getting tested every single year.
You can see what that does in the crash data. Personal flights, meaning weekend trips and family vacations, had 21.1 fatal accidents per million flight hours between 2012 and 2021. Student pilots on training flights, mostly in the same kind of small planes, had 2.3. So the people still learning to fly crash about 9 times less often than the people who already passed.
Compared to your car, personal flying in a small plane comes out about 27 times deadlier per hour. Worse than a motorcycle.
When investigators go through the wreckage, about 69% of the time they pin the crash on the pilot. Mechanical problems caused 7% of the deadly ones in 2021. Even an engine quitting, which is what everybody pictures, killed people in 6 of 57 cases that year.
The biggest killer is flying into bad weather, and it comes down to your inner ear.
There's fluid in there that sloshes around when you turn, and that's how your brain knows you're tilting. Hold a gentle turn for about 15 seconds and the fluid settles down, so your brain decides you're flying straight again. When you can see the horizon you catch it right away. Inside a cloud there's nothing to look at, so the plane keeps tipping, the nose drops, the speed climbs, and your body keeps telling you everything's fine.
Back in 1954, the University of Illinois put 20 pilots with zero instrument training into simulated clouds. Every one of them lost control of the plane. It took 178 seconds on average, a little under three minutes.
Pilots still end up in clouds they were never trained for, and more than 75% of those crashes kill someone. No weather accident in small planes is deadlier.
Small-plane people have joked about this since the 1950s. The Beechcraft Bonanza was one of the fastest single-engine planes you could buy, and so many wealthy doctors bought one and crashed it that people started calling it the "doctor killer." When people finally ran the numbers, the Bonanza crashed about as often as any other small plane. It just had a lot of rich owners with more money than flight time.
Look at the back of that cabin. One teenager's asleep under a plaid blanket and the other one's buried in a book. The biggest safety feature on that flight is the judgment of whoever's sitting up front.
Dan Patrick retweeted
just remember
people need zero evidence to accept a convenient lie
and endless evidence to accept an uncomfortable truth
Dan Patrick retweeted
Lying on a vibrating mattress for 40 minutes, combined with taking two pills that release nitric oxide into the body, enhanced the clearance of an Alzheimer's-related protein via the brain's waste-disposal system newscientist.com/article/259…
Dan Patrick retweeted
Look, if it weren’t for competition they could literally sell Opus 5.5 tokens forever and companies would pay for it until the end of time
The AI bubble bursting is going to be one of the biggest reality checks in tech history. These companies have spent years convincing us that AI is the future while burning billions, destroying jobs, draining natural resources and forcing products nobody asked for into our daily lives. Eventually, the hype has to meet reality.
Dan Patrick retweeted
3 eggs/day is the prescription to keep the brain from fading away
Higher choline intake thru diet = 33% lower odds of cognitive decline
Dan Patrick retweeted
The Dietary Polyphenol Epigallocatechin Gallate Delays Biological Aging by Activating Peroxisome Biogenesis and Peroxisomal Fatty Acid β‐Oxidation
Tea, both black and green, is the major source of EGCG
onlinelibrary.wiley.com/doi/…
Dan Patrick retweeted
Pro tip: just send the link to this article directly to your dot and it'll create a responsibilities page for you
Then go into that Page and delete the ones you don't want, and ask dot to add the ones you do want
Dan Patrick retweeted
We are part of something so awe inspiring.
We were taught that Earth orbits the Sun in a closed circle. In reality, Earth has never returned to the same point in space once in 4.5 billion years.
Right now, the Sun is carrying Earth and every planet around the center of the Milky Way at 230 km/s (828,000 km/h), more than 18,000 kilometers every 80 seconds.
Because the Solar System is tilted 60.2° to the galactic plane and bobs up and down through the galactic disc roughly every 30 million years, the planets trace open 3D corkscrew helices across deep space rather than flat loops.
The last time the Sun stood where it stands today, one Galactic Year (230 million years) ago, the very first dinosaurs were only beginning to appear on Earth. Since forming 4.6 billion years ago, our Sun has completed only 20 laps.
Dan Patrick retweeted
Absolutely incredible: MIT researchers say GPT-6 Astra improved a small Qwen model’s math score from 7.9% to 48.1% by directly editing just 0.016% of its weights, without gradient-based training.
The result points toward AI systems that can diagnose and improve other models directly, a potential step toward self-improving AI.
We asked GPT-6 Astra to edit Qwen3.5-0.8B weights to improve math.
It directly changed only 0.016% of weights, fixing 0.8B's reasoning loops & improving math up to 6x and even instruction following 3x, without gradients or training.
We call this Weight-Space Programming: frontier LLMs can now natively read/write neural network weights! 🧵
Blog: rikiyat.github.io/blog/weigh…
Readers added context they thought people might want to know
LLM was given weights explicitly as text in prompt and used code/forward passes (per authors' logs) to ablate Qwen looping direction, a known thinking-mode issue per model card. Primarily fixed repetition in that mode, not general 'natively' improving weights/math.
rikiyat.github.io/blog/weight-sp…
github.com/RikiyaT/lm_und…
huggingface.co/Qwen/Qwen3.5-0…
huggingface.co/RikiyaT/Qwen3.…
Dan Patrick retweeted
Running had similar effects to antidepressants for mental health, but significantly outperformed on physical health metrics.
Dan Patrick retweeted
Listen, I can get behind some high-quality content even if it’s AI-generated.
But the clearly AI formulated replies to posts are cringe. Like, you can’t put any constructive thought into a response?
What’s to be gained from this strategy anyway?
Dan Patrick retweeted
‘People don’t expect me to have a Yorkshire accent.’
Sir Patrick Stewart @sirpatstew has been embracing his Yorkshire roots with @SamiraAhmedUK on @bbcRadio4 this week.
Catch up with the full interview on @bbcsounds now. ⬇️
Patrick Stewart: It wasn't just an accent, it was a foreign language
Sir Patrick Stewart talks to Samira Ahmed about his Yorkshire roots.
Dan Patrick retweeted
Very cool! Babies’ internal clocks may even start developing before birth.
Expecting mothers with more regular sleep schedules also tended to have babies who slept more at night.
Your sleep schedule during pregnancy may help shape your baby’s body clock.




































