Ryan Marks (@ryanmmarks) header
Ryan Marks (@ryanmmarks) profile picture

Ryan Marks

@ryanmmarks

gene editor 🧬 • PhD Molecular Genetics @uoftmedicine • Connaught Public Impact Fellow @uoft • Cohn Lab Genetics & Genome Biology SickKids @SK_GGB @SickKidsnews

 Toronto, Ontario
Joined March 2023
  • Tweets40
  • Following653
  • Followers75
3Media
Photo by Ryan Marks (@ryanmmarks)Photo by Ryan Marks (@ryanmmarks)Photo by Ryan Marks (@ryanmmarks)
Ryan Marks retweeted
nature (@Nature) profile picture
nature
@Nature19 May 2025
The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time go.nature.com/4kqr3RK

World first: ultra-powerful CRISPR treatment trialled in a person

Nature - Immune-cell function improved in a teenager whose DNA was altered using prime editing.

nature.com
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In a world first, researchers report easing the symptoms of a baby boy with a rare, life-threatening disease by giving him a version of the #CRISPR gene editor tailored to a mutation he carries. scim.ag/3GU1Twg
Gene-editing therapy made in just 6 months helps baby with life-threatening disease

Gene-editing therapy made in just 6 months helps baby with life-threatening disease

Custom CRISPR paves the way for treating genetic disorders in tailormade ways

science.org
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A gene-editing treatment used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases #NBTNewsBeat nytimes.com/2025/05/15/healt…
Baby Is Healed With World’s First Personalized Gene-Editing Treatment (Gift Article)

Baby Is Healed With World’s First Personalized Gene-Editing Treatment (Gift Article)

The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.

nytimes.com
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Ryan Marks retweeted
CIHR IG IRSC (@CIHR_IG) profile picture
CIHR IG IRSC@CIHR_IG28 Feb 2025
Today is #RareDiseaseDay. Let’s come together to support those impacted by rare diseases. See what IG patient partners had to say about their involvement in IG, and what researchers and students have to say about their focus on rare diseases. cihr-irsc.gc.ca/e/54218.html
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💜🌍 Today is Rare Disease Day! 🌍💜 Together, we stand with the 300 million people worldwide living with rare diseases. In uniting on this day we can raise awareness, advocate for change, and promote a more equitable future! ⚖️ Learn more: rarediseaseday.org/
Image from Rare Disease Day (@rarediseaseday)
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CONNOR MCDAVID! OVERTIME WINNER! 🚨 CONNOR MCDAVID TRANCHE EN PROLONGATION! 🚨 #4Nations
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Ryan Marks retweeted
CIHR IG IRSC (@CIHR_IG) profile picture
CIHR IG IRSC@CIHR_IG18 Feb 2025
🔬Research students like Ryan highlight the importance of research and patient partners in our efforts to improving the lives of people affected by rare diseases. #RareDiseaseDay #RareDiseaseResearch #CIHRIG
“My research focuses on developing therapeutic applications of CRISPR/Cas9 and related genome editing technologies for the treatment of Duchenne muscular dystrophy. Rare Disease Day advocates for scientific progress driven by the lived experiences of patients and families. It’s a day to amplify voices and reaffirm our commitment to developing transformative therapies addressing urgent, unmet needs of the rare disease community. Their insights help shape meaningful research questions, ensuring that scientific advances translate into real-world benefits.”

ALT “My research focuses on developing therapeutic applications of CRISPR/Cas9 and related genome editing technologies for the treatment of Duchenne muscular dystrophy. Rare Disease Day advocates for scientific progress driven by the lived experiences of patients and families. It’s a day to amplify voices and reaffirm our commitment to developing transformative therapies addressing urgent, unmet needs of the rare disease community. Their insights help shape meaningful research questions, ensuring that scientific advances translate into real-world benefits.”

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Science Rendezvous is a free outdoor science festival to get kids and their families excited about all areas of science, technology, engineering, and mathematics. We are currently looking for volunteers to help us run the event. Link in bio to apply!
Image from SR UofT (St. George) (@UofTSR)
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On Remembrance Day, Canadians pause to honour members of the Canadian Armed Forces, past and present, for their service and sacrifice. They have bravely defended our borders, protected our citizens, and stood ready in the face of challenges at home and abroad. #CanadaRemembers
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🌟 We are getting ready to welcome students on Nov 6 for *Take Our Kids to Work* @SickKidsNews An exciting opportunity to explore the world of genetics 🧬✨. Can’t wait to see you all there! #FutureScientists #Genetics #genomics #toktw
Image from SickKids Genetics & Genome Biology Program (@SK_GGB)
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🚀 November 7th is Precision Child Health Day @SickKids Stop by our booth (4th floor, PSC) to hear about the incredible work our labs are doing to diagnose faster, predict better, and treat smarter. THIS is PrecisionHealth. #PCH2024 #Genetics #genomics
Image from SickKids Genetics & Genome Biology Program (@SK_GGB)
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Looking forward to sharing our work on new genome editing techniques for DMD!
ASGCT (@ASGCTherapy) profile pictureASGCT
@ASGCTherapy4 Nov 2024
JUST RELEASED: The full collection of #ASGCTBreakthroughs24 abstracts! Read + download more than 60 pieces of original research into #genetherapy and #celltherapy treatments for #MuscularDystrophy, and register to join us in Chicago. bit.ly/40QPrWj
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MoGen Professor Dr. James Dowling & his team at SickKids administered the first-ever in-clinic gene therapy for SPG50, a rare neurodegenerative disorder. This breakthrough treatment is a milestone in #PrecisionChildHealth. uoft.me/Mogen-News
MoGen Professor James Dowling and His Team Administer First-Ever In-Clinic Gene Therapy for SPG50...

MoGen Professor James Dowling and His Team Administer First-Ever In-Clinic Gene Therapy for SPG50...

SPG50 is a rare and severe neurodegenerative disorder that has long lacked effective treatments. Jim Dowling and his team at SickKids have made history by administering the first-ever in-clinic gene...

moleculargenetics.utoronto.ca
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Honoured to receive a Canada Graduate Scholarship - Doctoral (CGS-D) from @CIHR_IRSC ! Very excited to continue our work developing precision genome editing therapeutics in the @ronald_cohn & @EIvakine labs! @SickKidsNews @MoGen_Grad @uoftmedicine @UofT
Image from Ryan Marks (@ryanmmarks)
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Today is #RareDiseaseDay, and at @SickKidsNews, resilient children like Rian continue to defy the odds. 💙 At 11 months old, Rian’s family received a diagnosis – something many kids with rare diseases are still looking for.
Image from SickKids Foundation (@sickkids)
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Today, in @NatureBiotech we share our perspectives on recent developments in prime editing enabling various high efficiency applications in vivo and identify future opportunities for precision genome editing in the clinic. #NBTNV
Nature Biotechnology (@NatureBiotech) profile pictureNature Biotechnology
@NatureBiotech29 Jan 2024
Replying to @NatureBiotech
An optimized toolkit for prime editing #NBTNV go.nature.com/3HCAlIX
Image from Nature Biotechnology (@NatureBiotech)
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🔬 Will you be an undergrad and med student in Fall 2024? Are you searching for an opportunity to get hands-on experience in a #research lab? Look no further than the SickKids Summer Research Program! Learn more & apply now: sickkids.ca/ssure
Image from The Hospital for Sick Children (SickKids) (@SickKidsNews)
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We’re proud of @DrLisaRobinson for her appointment as Dean of @uoftmedicine. She's an outstanding clinician-scientist, mentor & leader who has lifted care, research & education at SickKids, #UofT & beyond to new heights. Congratulations on this achievement bit.ly/3NpbJ9U
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To those we loved and lost, To those who served and never came home, To those who continue to serve, Today on #RemembranceDay, and every day in between, We will remember them.

The Last Post – performed by members of The Central Band of the CAF

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