Ryan Marks (@ryanmmarks) header
Ryan Marks (@ryanmmarks) profile picture

Ryan Marks

@ryanmmarks

gene editor 🧬 • PhD Molecular Genetics @uoftmedicine • Connaught Public Impact Fellow @uoft • Cohn Lab Genetics & Genome Biology SickKids @SK_GGB @SickKidsnews

 Toronto, Ontario
Joined March 2023
  • Tweets40
  • Following653
  • Followers75
3Media
Photo by Ryan Marks (@ryanmmarks)Photo by Ryan Marks (@ryanmmarks)Photo by Ryan Marks (@ryanmmarks)
Ryan Marks retweeted
nature (@Nature) profile picture
nature
@Nature19 May 2025
The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time go.nature.com/4kqr3RK
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In a world first, researchers report easing the symptoms of a baby boy with a rare, life-threatening disease by giving him a version of the #CRISPR gene editor tailored to a mutation he carries. scim.ag/3GU1Twg

Gene-editing therapy made in just 6 months helps baby with life-threatening disease

Custom CRISPR paves the way for treating genetic disorders in tailormade ways

science.org
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A gene-editing treatment used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases #NBTNewsBeat nytimes.com/2025/05/15/healt…
Baby Is Healed With World’s First Personalized Gene-Editing Treatment (Gift Article)

Baby Is Healed With World’s First Personalized Gene-Editing Treatment (Gift Article)

The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.

nytimes.com
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Ryan Marks retweeted
CIHR IG IRSC (@CIHR_IG) profile picture
CIHR IG IRSC@CIHR_IG28 Feb 2025
Today is #RareDiseaseDay. Let’s come together to support those impacted by rare diseases. See what IG patient partners had to say about their involvement in IG, and what researchers and students have to say about their focus on rare diseases. cihr-irsc.gc.ca/e/54218.html
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💜🌍 Today is Rare Disease Day! 🌍💜 Together, we stand with the 300 million people worldwide living with rare diseases. In uniting on this day we can raise awareness, advocate for change, and promote a more equitable future! ⚖️ Learn more: rarediseaseday.org/
Image from Rare Disease Day (@rarediseaseday)
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CONNOR MCDAVID! OVERTIME WINNER! 🚨 CONNOR MCDAVID TRANCHE EN PROLONGATION! 🚨 #4Nations
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Science Rendezvous is a free outdoor science festival to get kids and their families excited about all areas of science, technology, engineering, and mathematics. We are currently looking for volunteers to help us run the event. Link in bio to apply!
Image from SR UofT (St. George) (@UofTSR)
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On Remembrance Day, Canadians pause to honour members of the Canadian Armed Forces, past and present, for their service and sacrifice. They have bravely defended our borders, protected our citizens, and stood ready in the face of challenges at home and abroad. #CanadaRemembers
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🌟 We are getting ready to welcome students on Nov 6 for *Take Our Kids to Work* @SickKidsNews An exciting opportunity to explore the world of genetics 🧬✨. Can’t wait to see you all there! #FutureScientists #Genetics #genomics #toktw
Image from SickKids Genetics & Genome Biology Program (@SK_GGB)
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🚀 November 7th is Precision Child Health Day @SickKids Stop by our booth (4th floor, PSC) to hear about the incredible work our labs are doing to diagnose faster, predict better, and treat smarter. THIS is PrecisionHealth. #PCH2024 #Genetics #genomics
Image from SickKids Genetics & Genome Biology Program (@SK_GGB)
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MoGen Professor Dr. James Dowling & his team at SickKids administered the first-ever in-clinic gene therapy for SPG50, a rare neurodegenerative disorder. This breakthrough treatment is a milestone in #PrecisionChildHealth. uoft.me/Mogen-News
MoGen Professor James Dowling and His Team Administer First-Ever In-Clinic Gene Therapy for SPG50...

MoGen Professor James Dowling and His Team Administer First-Ever In-Clinic Gene Therapy for SPG50...

SPG50 is a rare and severe neurodegenerative disorder that has long lacked effective treatments. Jim Dowling and his team at SickKids have made history by administering the first-ever in-clinic gene...

moleculargenetics.utoronto.ca
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Today is #RareDiseaseDay, and at @SickKidsNews, resilient children like Rian continue to defy the odds. 💙 At 11 months old, Rian’s family received a diagnosis – something many kids with rare diseases are still looking for.
Image from SickKids Foundation (@sickkids)
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🔬 Will you be an undergrad and med student in Fall 2024? Are you searching for an opportunity to get hands-on experience in a #research lab? Look no further than the SickKids Summer Research Program! Learn more & apply now: sickkids.ca/ssure
Image from The Hospital for Sick Children (SickKids) (@SickKidsNews)
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We’re proud of @DrLisaRobinson for her appointment as Dean of @uoftmedicine. She's an outstanding clinician-scientist, mentor & leader who has lifted care, research & education at SickKids, #UofT & beyond to new heights. Congratulations on this achievement bit.ly/3NpbJ9U
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To those we loved and lost, To those who served and never came home, To those who continue to serve, Today on #RemembranceDay, and every day in between, We will remember them.

The Last Post – performed by members of The Central Band of the CAF

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Are you an Indigenous, Black or Filipino high school student? Want a career in science? Our paid six-week StAR program allows high school students to intern in an #SKResearch lab! 🔬 Learn more & apply by January 29 ➡️ bit.ly/3FT9asB #NationalSTEMDay
Researcher in a lab looking through a microscope.

ALT Researcher in a lab looking through a microscope.

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It's #WorldDuchenneAwarenessDay & today CRD is celebrating the community that inspires us - the researchers, families & boys that are breaking down barriers. Together, we will continue to create a better future for everyone impacted by #Duchenne. #WDAD2023 #WDAD #breakingbarriers
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🔬 Inspiring the next generation of scientists! Our MoGen grad students — Sina Fatehi, Ryan Marks, Sophie Karolczak, Yin Chen Wan, Francis Lefebvre & Chen Chen — spoke and connected with high school students at SMP and STEAM-D; programs run by @TemertyMedicine. #Mentorship
Image from Department of Molecular Genetics, U of T (@MoGen_Grad)
Image from Department of Molecular Genetics, U of T (@MoGen_Grad)
Image from Department of Molecular Genetics, U of T (@MoGen_Grad)
Image from Department of Molecular Genetics, U of T (@MoGen_Grad)
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Ryan Marks retweeted
ASGCT (@ASGCTherapy) profile picture
ASGCT
@ASGCTherapy13 Jul 2023
Last month, @US_FDA approved the first-ever #genetherapy for #Duchenne #musculardystrophy. Read comments from ASGCT President Jeffrey Chamberlain, PhD, who has pioneered development of micro-dystrophin GTs, about the significance of this approval. ow.ly/vP2q50PaEvW
Image from ASGCT (@ASGCTherapy)
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Ryan Marks retweeted
Feng Zhang (@zhangf) profile picture
Feng Zhang
@zhangf28 Jun 2023
Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in @Nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. nature.com/articles/s41586-0…
Fanzor is a eukaryotic programmable RNA-guided endonuclease

Fanzor is a eukaryotic programmable RNA-guided endonuclease

Nature - Fanzor is shown to be an RNA-guided DNA endonuclease, demonstrating that such endonucleases are found in all domains of life and indicating a potential new tool for genome engineering...

nature.com
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