@youklab

Physicist & Quantitative Biologist @ UIUC Physics 🇨🇦🏳️‍🌈

 UIUC
youklab.org
Joined August 2014
  • Tweets368
  • Following492
  • Followers739
62Media
1/n: How slowly can life progress? It’s obvious that cells cannot duplicate in a nanosecond. But is there a limit to how slowly cell's life can progress without stopping? We answered this for budding yeast by decreasing temperature [movie of yeast at 1 C]: biorxiv.org/content/10.1101/…
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Why are some non-antibiotic drugs toxic to bacteria 💊☠️🦠? Do they work like standard #antibiotics (ABX)? Our latest work by @MarianaNoto published @ScienceMagazine addresses this fundamental question (1/n) science.org/doi/10.1126/scie…
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It's official. Thanks to the MIRA grant, my lab gets to live to fight another day (or five years!). We are now actively recruiting. Spread the word, and reach out if you are interested in doing a postdoc with me. One position is available jointly with Terry Hwa's lab. Exciting!
Sergey Kryazhimskiy 🇺🇦@skryazhi17 Oct 2023
I am cautiously optimistic that my lab will have an open postdoc position in 2024. If you are potentially interested, please reach out. Or if you know somebody who might be interested, please connect us. My email is on our lab website sklab.science
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New manuscript from former @MitacsCanada student Mathis and postdoc Jannik! Analyzes the role of information flow in a model two-component molecular motor. @SFUResearch @SFU_Science @SFUPhysics Thanks for support @NSERC_CRSNG @TIPS_SPIIE
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Microbial life in slow and stopped lanes @TrendsMicrobiol from @youklab sciencedirect.com/science/ar…
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Congrats to Diederik Laman Trip, our lab's former student, for receiving 2023 APS PhD-thesis prize in biological physics! (@ApsDbio @APSphysics ) [1/2] aps.org/programs/honors/priz…
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A joy of being a PI is learning from "trainees". I learned so much from Diederik. I'm immensely proud and privileged to have been associated with this remarkable scientist. These two papers describe his work [2/2]: 1. nature.com/articles/s41564-0… 2. nature.com/articles/s41467-0…
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What if we could learn cellular automata models of biological pattern formation directly from data? New preprint by Alex Richardson, Tibor Antal, @DrAlgernon, and myself: arxiv.org/abs/2310.14809

Learning spatio-temporal patterns with Neural Cellular Automata

Neural Cellular Automata (NCA) are a powerful combination of machine learning and mechanistic modelling. We train NCA to learn complex dynamics from time series of images and PDE trajectories. Our...

arxiv.org
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It turns out that sparkling water and raisins are *fascinating*. My daughter and I happened upon this effect playing together in the kitchen a long time ago, and I couldn't help but explore the system more deeply... 1/n arxiv.org/abs/2308.12927
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Interested in quantitative biology of microbial behavior and information processing? We are looking for postdocs, PhD students, and research assistants. Pls spread the word! imb.sinica.edu.tw/en/faculty…
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Great postdoc program at an amazingly collaborative intellectual environment. Speaking from personal experience. Feel free to reach out if you have any questions.
MPI-PKS Dresden@mpi_pks10 Aug 2023
The call of the ELBE Postdoctoral Fellows Program at the Center for Systems Biology Dresden @csbdresden @mpicbg @mpi_pks @tudresden_de is now open! Great opportunity for interdisciplinary research, apply here (deadline 25 Sept) csbdresden.de/join-us/as-a-p…
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Replying to @Ariel_4321 @BarkaiLab
We found that this mechanism can lead to higher specificity and faster search, and analyze the "design principles" involved. Work led by Wencheng Ji @wencheng__ji, in collaboration with Ori Hachmo and Naama Barkai. arxiv.org/abs/2307.11180 3/3

Design principles of transcription factors with intrinsically...

Transcription Factors (TFs) are proteins crucial for regulating gene expression. Effective regulation requires the TFs to rapidly bind to their correct target, enabling the cell to respond...

arxiv.org
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Motivated by experiments in the Barkai lab @BarkaiLab on the role of Intrinsically Disordered Regions in the search process in eukaryotes, we considered the search process of a *polymer* with multiple, weak bindings to a region flanking the target site on the DNA. 2/3
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Opportunities to work with an exceptional quantitative biologist, who speaks both theoretical and experimental languages
Wei-Hsiang Lin@WeiHsiangLin37 Aug 2023
Our group (at Taipei, Taiwan) is looking for postdoc and research assistant! If you are interested in Q-bio, nonlinear physics or cellular modeling, please contact us: [tinyurl.com/mr332pwj] [tinyurl.com/5e7nvrw7]
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Our group (at Taipei, Taiwan) is looking for postdoc and research assistant! If you are interested in Q-bio, nonlinear physics or cellular modeling, please contact us: [tinyurl.com/mr332pwj] [tinyurl.com/5e7nvrw7]
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Hyun Youk retweeted
Athma Pai@athmapai1 Aug 2023
Long-read RNA-seq promises to revolutionize RNA biology with  id'ing and quantifying full-length mRNA isoforms. However, be wary of read quality and interpretation. A tweetorial on our new preprint (1/6): biorxiv.org/cgi/content/shor… #RNAseq #LongReadSequencing 🧬🔬
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Just out in PNAS: how do fibroblasts respond to topological defects imposed on them? Modeling by @kurmankaiyrbek, great collaboration with @SerraLab_LC + Kirsten Endresen for the experiments! doi.org/10.1073/pnas.2301197…
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Very excited to share my first (co-)first author paper! We reveal GPCR domains at the plasma membrane (PM) of living cells & we find ways to modulate their spatial organisation. Interested? Here, is a thread 🧵rdcu.be/dg3bd
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Great @EMBO_YIP meeting on chromatin & transcription right across the species & experimental approaches spectrum. Attendees from Bangalore to Boston in Copenhagen. Thanks for the open data sharing & superb organization by Sebastian @marquardtlab & Daniel Messerschmidt @EMBOPress
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Totally agree fab @EMBO_YIP chromatin and transcription meeting. Presentations & discussions were great, I learned a lot. Thank you to Sebastian @marquardtlab , Daniel Messerschmidt for kicking it off - and let's keep the ball rolling!
Bernd Pulverer@BerndPulverer7 Jul 2023
Great @EMBO_YIP meeting on chromatin & transcription right across the species & experimental approaches spectrum. Attendees from Bangalore to Boston in Copenhagen. Thanks for the open data sharing & superb organization by Sebastian @marquardtlab & Daniel Messerschmidt @EMBOPress
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PSFs are just Gaussians, right?? Not when your fluorophore💡is close to a nanoparticle 🟠! Excited to share our preprint in which we present a novel PSF-fitting approach for localization microscopy near nanoparticles.🥳 doi.org/10.48550/arXiv.2306.… Main findings below: [1/9]
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