Professor. Chemical Biology/Synthetic Biology. Tweets are personal opinions. https://xitter.cf/t.co/YiwoIk2LOp
Boston
Joined November 2013
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🚨🚨 A comprehensive review by Rahul Sarkar and @Manas_M_Joshi on encoded bioorthogonal noncanonical amino acids, chemical reactions that enable their chemoselective labeling, advantages and limitations of each approach, and the applications they unlock! onlinelibrary.wiley.com/doi/…
Thank you @OnoInitiative for the support!
The 2026 Ono Initiative Award is presented to @BalskusLab, @brian_belardi, @AChemSynBio as noted. Congratulations!
Emily P. Balskus, @HarvardCCB
Brian Belardi, @UTChemistry
Abhishek Chatterjee, @BostonCollege
Abhishek Chatterjee retweeted
Welcome Senior Editor Abhishek Chatterjee, PhD, who brings expertise in chemical and synthetic biology, proteomics, novel bioconjugation chemistries, and therapeutic protein conjugates. Learn more about Molecular Cancer Therapeutics: brnw.ch/21x3LB2 @BostonCollege
Abhishek Chatterjee retweeted
Co-Translational Incorporation of (R)- and (S)-β2-Hydroxyacids In Vivo: Directed Evolution of Efficient Aminoacyl-tRNA Synthetases | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…
Chintan's @cpsoni_74 work demonstrating the efficient incorporation of non-α-amino acid backbones into proteins expressed in both E. coli and mammalian cells, just came out! A great collaborative effort from @cgem_cci! pubs.acs.org/doi/10.1021/jac…
An accompanying paper from @AlannaSchepartz and Jamie Cate groups shows how the E. coli ribosome supports the incorporation of the non-α-amino acid monomers pubs.acs.org/doi/10.1021/jac…
Starting 2026 with Quan Pham's paper expanding the chemical toolbox for engineering AAV
- New bioorthogonal labeling, including IEDDA, for efficient macromolecule attachment
- Incorporation of two different chemistries for dual capsid labeling & much more:
onlinelibrary.wiley.com/doi/…
Excited to share our work with Eranthie Weerapana and Tim van Opijnen, co-led by @conor_loynd, @SinghaSoumya, and @SCanarelli! We introduce a new generation of BONCAT tools for versatile characterization of newly synthesized proteins in pathogenic bacteria rdcu.be/eI4M5
Abhishek Chatterjee retweeted
A facile chemical strategy to synthesize precise AAV-protein conjugates for targeted gene delivery dlvr.it/TMfgwR
Cool work from @Han_Xiao2016 on site-specific incorporation of an environment-sensitive fluorescent noncanonical amino acid to visualize protein microenvironment changes in living cells
Genetically incorporating environment-sensitive noncanonical amino acids containing rotor-based fluorophores to target proteins enables real-time visualization of microenvironment changes in protein substructures
nature.com/articles/s41589-0…
Our work @cgem_cci on co-translational incorporation of a noncanonical monomer into a protein, followed by its triggered post-translational chemical rearrangement, yielding novel backbone modifications. nature.com/articles/s41589-0…
Abhishek Chatterjee retweeted
Happy to see this new T7 replicon based orthogonal replication system in E. coli. Congrats to the Diercks and Schultz lab teams at Scripps Research! science.org/doi/10.1126/scie…
Abhishek Chatterjee retweeted
I discuss the urgent crisis from the loss of federal support of science in the US and recent clinical gene editing breakthroughs with @WalterIsaacson & @amanpour on @AmanpourCoPBS, airing on @PBS tonight at 11 pm ET, and on @cnni earlier today. Pls share!
youtube.com/watch?v=8YhJM6zx…
Abhishek Chatterjee retweeted
Today in @ScienceMagazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with @SternbergLab.
1/13
drive.google.com/file/d/1I-U…
Abhishek Chatterjee retweeted
Writing in @J_A_C_S, we report a sugar-derived single-addition monomer that can be added together with other monomers in #ROMP and install functional groups at the chain end of metathesis polymers. #glycotime #polymer #NSFfunded
pubs.acs.org/doi/10.1021/jac…
Abhishek Chatterjee retweeted
NIH is centralizing peer review of all applications for grants, cooperative agreements and research and development contracts within the agency’s @CSRpeerreview. This is expected to save NIH more than $65 million annually & make the review process more efficient. go.nih.gov/iGmUyfH
Abhishek Chatterjee retweeted
This isn't science fiction. This is real sequencing biotechnology just introduced by Roche. Wild and wonderful.
Abhishek Chatterjee retweeted
We are excited to report the discovery of TIGRs, a widely-occurring RNA-guided system found in bacteria and their viruses. TIGRs consist of a peculiar repeat region which is transcribed into RNA and processed into multiple guide RNAs to direct TIGR-associated proteins to their DNA targets. science.org/doi/10.1126/scie…
