Biochemistry of immunology, protein structure and protein folding. Flipping the classroom into the digital world for Tulane students and everyone else.
Tulane University
Joined April 2013
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Sam Landry retweeted
Based on pioneering work by @BAGarvy and Fran Lund that B cells are key antigen presenting cells for Pneumocystis (a common fungal pneumonia in infants), @MNoell_12 figured infants must have anti-fungal IgMs that predict T cell responses. They do! insight.jci.org/articles/vie…
Sam Landry retweeted
This is why 2nd boosters should be available for all health care workers now. A report on ~30,000 Israeli HCWs indicates 65% lower risk of breakthrough infections during the Omicron wave (4 vs 3 doses) @JAMANetworkOpen
jamanetwork.com/journals/jam…
I’m a Virologist, and I’m Setting the Record Straight on Variants and Reinfections nytimes.com/2022/07/22/opini…
Sam Landry retweeted
Just published @NEJM
During Omicron, the 2-shot mRNA vaccine effectiveness among >250,000 children age 5 to 11 years old:
vs hospitalizations was very high—83%
vs PCR confirmed infections 65%
nejm.org/doi/full/10.1056/NE…
Sam Landry retweeted
Although the handshake and other types of physical contact are gradually returning, they have been on hiatus due to #COVID19. Such changes have already altered the epidemiology of a range of infectious diseases.
Learn more in a new #SciencePerspective: fcld.ly/al7glzl
Sam Landry retweeted
Researchers know little about the global diversity and distribution of #soil fungi
To change that - @spununderground - a new nonprofit is funding a global network of subterranean sleuths
Learn more: science.org/content/article/… via @ScienceMagazine
Sam Landry retweeted
What is immune imprinting and why it is important?
A superb explainer
“Our first encounter with the spike antigen, either through infection or vaccination, shapes our subsequent pattern of immunity through immune imprinting" —@BoytonRosemary
ft.com/content/4f71ac72-0aff…
Sam Landry retweeted
When it comes to #SARSCoV2 and Covid, it's important to keep your eyes on the ball. The ball is BA.5 and here is what we know about it
erictopol.substack.com/p/the…
Second paper showing unfavorable imprinting by omicron, likely meditated by antigen processing...Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure science.org/doi/10.1126/scie…
Sam Landry retweeted
A new report on Covid reinfections is particularly concerning. I've written about it here erictopol.substack.com/p/a-r…
T cells could account for slower loss of vaccine protection against severe disease.
A @NatureMedicine paper presents a model that predicts the effectiveness of COVID-19 vaccines against circulating SARS-CoV-2 variants, which could help guide more rapid public health and research responses to new variants of concern. go.nature.com/3O5b8Za
Graph is from experience.arcgis.com/experi…. Green, patients; orange, ventilators. Cases not shown.
On Jan 5 the State would have actually had 400,000 cases and reported (accurately?) 1412 hospitalizations (0.35% of cases). All this to say that the current infection rate is probably 194/0.0035=55,000. That's 52 times higher than reported. I'm not going out again for a while.
As we approached the peak of Omicron (Jan 5), 12,757 cases were reported, but the number was likely higher than 10% of the population. Tulane was testing like crazy and getting 12.5 % positive.
COVID infections are grossly under-reported. On May 31st, the 7-day average was reportedly 1,064, and hospitalizations were at 194, or 18%. Of course, we know that 18% of COVID+ people are not going to hospitals.
Jan 5 the State would have actually had 400,000 cases, and reported (accurately?) 1412 hospitalizations (0.35% of cases). All this to say that the current infection rate is probably 194/0.0035=55,000. That's 52 times higher than reported. I'm not going out again for a while.
This quoted post is unavailable.
As we approached the peak of Omicron (Jan 5), 12,757 cases were reported, but the number was likely higher than 10% of the population. Tulane was testing like crazy and getting 12.5 % positive.
This quoted post is unavailable.
Bargain compared to gas tax.
Louisiana owners of all-electric vehicles will be charged annual fees of $110, while hybrid owners will be charged $60. wwltv.com/article/travel/lou…
Oh well. Here's motivation to cultivate more thoughtfully. The concept of one crop one herbicide resistance needs to go. @BeesNativePlant
Exposure to glyphosate—one of the most widely used herbicides worldwide—can significantly impair bumblebees’ collective ability to maintain hive temperature, specifically when food is scarce, researchers report in Science. fcld.ly/io2opqh
Sam Landry retweeted
Gov Edwards @LouisianaGov What a great selection is the the Gulf Frittillary for our state butterfly.