GM²| 🤹‍♂️ | ẞĪÕTĒÇH | 🪄 $IDIA 🐛;🦋; 🐦‍🔥

In case you missed our latest insight on new investment into Matter Machine Technologies (MMT)… 🌍 We take a closer look at why we’re backing the University of Liverpool spinout, which is combining AI with world-leading materials science to accelerate the discovery of new materials for applications spanning batteries, clean energy and computing. 🔗 Read more: lnkd.in/da5-dnWX

this is really why we need at least a datacenter/home:

It’s been an exciting week for portfolio company @IksudaT, which has announced encouraging clinical data from two of its antibody drug conjugate (ADC) programmes. 🩸 IKS03 has shown promising early anti-tumour activity in patients with advanced B-cell lymphoma, including patients previously treated with CAR-T therapy. 🎗️ IKS014 has demonstrated promising activity across HER2-expressing solid tumours, including in breast cancer patients previously treated with Enhertu (T-DXd). Both programmes also demonstrated encouraging and manageable safety profiles in these early-stage studies. Congratulations to the Iksuda Therapeutics team👏 Read the full press releases: lnkd.in/dbY9UMQD

Sharing my art until the algorithm finds me people who will like it!

Yes it is a new one. Not sure how new but it’s called daridorexant (brand name Quviviq). It’s non addictive and can be taken long term. I used to sleep maybe 1030-2 on a good night. Now I don’t wake until 5-6. Huge difference.

daridorexant has a lower half life - i switched to it from lem and haven't looked back. no more morning grogginess!

Idorsia: Breakthrough Therapy Designation granted by the FDA for daridorexant in pediatric insomnia disorder #Idorsia, #IDIA crweworld.com/article/news-p…

There is evidence that some with diagnosed ADHD are actually sleep deprived. I am not sure that DORAs like daridorexant are the correct solution, though I will note that DORAs contrary to many other sleep medication tend to protect sleep architecture (deep sleep).

CONNOR MCDAVID HAS MORE ASSISTS THAN ANY OTHER PLAYER HAS POINTS!!! 🤯

🚨 TIRZEPATIDE: FROM 2.5MG TO 15MG — WHAT DO CLINICAL STUDIES ACTUALLY SHOW? Tirzepatide is one of the most discussed medications in metabolic health and weight management. But understanding the science means looking beyond the numbers. 🧬 🧬 1. HOW DOES TIRZEPATIDE WORK? Unlike semaglutide, which targets the GLP-1 receptor, tirzepatide activates two pathways: 🔹 GLP-1: Helps regulate appetite, food intake, and blood glucose. 🔹 GIP: Plays a role in insulin secretion and metabolic regulation. 💡 This dual-receptor activity is what makes tirzepatide different. 📊 2. WHAT DID THE SURMOUNT-1 TRIAL STUDY? The 72-week Phase 3 trial included 2,539 adults with obesity or overweight and weight-related health conditions, without diabetes. Participants were assigned to: 💉 5mg once weekly 💉 10mg once weekly 💉 15mg once weekly ⚖️ Placebo The study included gradual dose escalation and lifestyle support. 📉 3. WHAT WERE THE RESULTS AT 72 WEEKS? Average body-weight changes: 🟢 5mg: −15.0% 🔵 10mg: −19.5% 🟣 15mg: −20.9% ⚪ Placebo: −3.1% 📌 These are clinical trial averages, not guaranteed individual outcomes. ⚖️ 4. WHY WAS DOSE ESCALATION PART OF THE STUDY? Participants did not start at their final target dose. The trial used gradual increases over a 20-week escalation period. Why does this matter? ⚠️ Gastrointestinal side effects were among the most common adverse events, including: • Nausea • Diarrhea • Constipation • Vomiting These effects were particularly relevant during dose escalation. 💡 Key takeaway: A higher dose is not automatically better for everyone. 🔬 5. WHAT DOES THE APPROVED LABEL SAY? In the United States, the Zepbound prescribing information describes: • A 2.5mg starting dose • Increases of 2.5mg after at least four weeks, when appropriate • Maintenance doses of 5mg, 10mg, or 15mg once weekly for weight reduction ⚕️ This is prescription-medication information, not a self-treatment guide. Treatment decisions require a qualified healthcare professional. 💪 6. THE BIGGER PICTURE Weight management is about more than the number on the scale. 🥗 Nutrition 💪 Adequate protein and resistance training 😴 Sleep and recovery 🩺 Long-term medical follow-up All play important roles in overall health and body composition. 🧠 Tirzepatide demonstrates how targeting multiple metabolic pathways can influence weight regulation. But clinical results should never be confused with guaranteed individual outcomes. 👇 WHAT WOULD YOU LIKE TO UNDERSTAND NEXT? A️⃣ Tirzepatide vs. Semaglutide B️⃣ Tirzepatide vs. Retatrutide C️⃣ How clinical trials evaluate dose escalation and side effects #Tirzepatide #GLP1 #GIP #MetabolicHealth #WeightManagement #PeptideScience

🚨BREAKING: Weight loss transformations lead to nearly 2x MORE divorce, Swedish study of 12,000+ people find!

BREAKING: Retatrutide trial had 9 major heart events on the drug vs 1 on placebo

Crazy stat: Tech momentum is now below the dot-com bust, per Morgan Stanley

1. More billionaires are associated with less poverty. 2. Increasing billionaires per capita by ten fold lowers poverty by 43 percentage points. 3. Sweden has more billionaires per 10M people than the U.S. (34 vs 30) 4. Correlation is fairly strong (R-squared of 0.6 for two variable cross-section data) 4. Since the graph is only a correlation, what do you think is the cause? 🔗in🧵

It's the Great Sweater Reveal, Charlie Brown! 🐾 Here's your first look at the P-Bruins all-new Snoopy-inspired sweaters, to be worn January 16th & 17th on Peanuts Weekend at The AMP! 🥜