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DuharcourtLab (@DuharcourtLab) profile picture

DuharcourtLab

@DuharcourtLab

Paramecium genome(s) afficionado; @IJMonod, Paris, France; @sandraduharcourt.bsky.social

 Institut Jacques Monod, Paris, France
Joined November 2018
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  • Followers546
Preprint alert. We’re thrilled to announce the latest work from our lab: The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium. A thread with our key findings: (1/6) biorxiv.org/content/10.1101/…
The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in...

The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in...

Ciliates undergo developmentally programmed genome elimination, in which small RNAs direct the removal of target DNA segments, including transposable elements. At each sexual generation, the develo...

biorxiv.org
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now at @sandraduharcourt.bsky.social
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#SaveTheDate 🗓️7th June 📍Institut Jacques Monod Invited by the @DuharcourtLab, Nick Irwin will give an Institut Jacques Monod Seminar on the theme "Self-assembling viral histones unravel early nucleosome evolution" ➡️urlz.fr/qCsx
Image from Institut Jacques Monod (@IJMonod)
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❗@IJMonod seminar❗ "Self-assembling viral #histones unravel early #nucleosome evolution" by Nick Irwin (@dinokaryon, @gmivienna, @viennabiocenter) 🧬 Invited by @DuharcourtLab 🗓️Tomorrow, Friday, June 7, at 11.45 am 📍François Jacob room ijm.fr/nick-irwin/

Séminaire IJM – Nick Irwin – 7/06/2024

Invité par l'équipe Duharcourt, Nick Irwin (Gregor Mendel Institute, Vienna BioCenter) présentera un séminaire de l'Institut Jacques Monod sur le thème : Self-assembling viral histones unravel early...

ijm.fr
Institut Jacques Monod (@IJMonod) profile pictureInstitut Jacques Monod@IJMonod10 May 2024
#SaveTheDate 🗓️7th June 📍Institut Jacques Monod Invited by the @DuharcourtLab, Nick Irwin will give an Institut Jacques Monod Seminar on the theme "Self-assembling viral histones unravel early nucleosome evolution" ➡️urlz.fr/qCsx
Image from Institut Jacques Monod (@IJMonod)
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Congratulations Thomas! #ProudPI
PeerJ Publishing (@thePeerJ) profile picturePeerJ Publishing@thePeerJ6 Jun 2024
PeerJ congratulates Thomas Balan (@Thomas_Balann) and Clément Goubert (@clementgoubert) award winners at ICTE 2024 (@ICTE2024) Learn more about their research on the PeerJ blog bit.ly/4ecaIxz #Transposableelements #mobileDNA #DNA @clementgoubert
Image from PeerJ Publishing (@thePeerJ)
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#ICTE2024 congrats to the three poster winners: @clementgoubert , @toma_bln and Victor Billon!
Image from International congress on transposable elements (@ICTE2024)
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Brilliant keynote by Sandra @DuharcourtLab on the extraordinary epigenetic gymnastics of TE DNA elimination in ciliates. So much good science at #ICTE2024 it’s guaranteed to send me back home with no brain left 🤯🤯🤯
Image from Cedric🧬➰🧬Feschotte (@CedricFeschotte)
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DuharcourtLab retweeted
Paul Conduit (@PaulConduit) profile picture
Paul Conduit@PaulConduit15 Apr 2024
🚨‼️postdoc positions available‼️🚨 If you’re interested in #microtubules and #neurons and you want to work within a friendly but ambitious team in the city of lights, then apply now! #drosophila #microscopy @IJMonod @Fondation_BS @CNRS
Image from Paul Conduit (@PaulConduit)
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Happy to share our review dx.doi.org/10.1002/wrna.1848 we highlight the similarities and differences between ciliates and other eukaryotes in small-RNA-directed chromatin silencing. @IJMonod @CNRSbiologie @toma_bln @DannyHoloch
Small‐RNA‐guided histone modifications and somatic genome elimination in ciliates

Small‐RNA‐guided histone modifications and somatic genome elimination in ciliates

In ciliates, an ancestral pathway for transposable element repression by small RNAs and histone methyltransferases has evolved into a highly orchestrated process to eliminate unwanted sequences from...

wires.onlinelibrary.wiley.com
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Happy to share our last work: "Alternative silencing states of Transposable Elements in Arabidopsis" biorxiv.org/content/10.1101/…
Alternative silencing states of Transposable Elements in Arabidopsis

Alternative silencing states of Transposable Elements in Arabidopsis

The DNA methylation/H3K9me2 and Polycomb-group proteins (PcG)-H3K27me3 pathways have long been considered mutually exclusive and specific to TEs and genes, respectively. However, H3K27me3 can be...

biorxiv.org
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Hi! Only two more weeks to register for #ICTE2024 & to submit an abstract for a talk on one of the different topics below: 1) TEs, genome evolution and adaptation 2) TEs in health and disease 3) TE control & epigenetics 4) Transposition mechanisms and applications See you soon!
Image from International congress on transposable elements (@ICTE2024)
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Our paper elucidating the process by which chromatin orchestrates non-coding RNA transcription for small RNA-chromatin communication has been officially published online in eLife! doi.org/10.7554/eLife.95337 @eLife #Tetrahymena #ciliate
A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA...

A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA...

The identification of a SUMO E3 ligase engaged in lncRNA transcription, subsequently leading to target-directed small RNA degradation, reveals an unexplored layer of regulatory mechanisms within...

elifesciences.org
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A dual histone code specifies the binding of heterochromatin protein Rhino to a subset of piRNA source loci biorxiv.org/cgi/content/shor… #biorxiv_molbio
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DuharcourtLab retweeted
Itai Yanai (@ItaiYanai) profile picture
Itai Yanai
@ItaiYanai8 Jan 2024
Out today in @NatureBiotech! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. nature.com/articles/s41587-0…… @MartinJLercher
Image from Itai Yanai (@ItaiYanai)
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Dear TE family, it is time! 🏃‍♀️🏃‍♂️ The early-bird registration ends January 15th already! Abstract for talks ends February 15th! Start procrastinating by doing something useful: register to #icte2024 ! See you soon! #transposon
Image from International congress on transposable elements (@ICTE2024)
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#JobOffer 💼Ingénieur d'études en biologie moléculaire (H/F) 📍@DuharcourtLab 🗓️ 22 janvier 2024 Candidatez avant le 28 décembre➡️emploi.cnrs.fr/Offres/CDD/UM…
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DuharcourtLab retweeted
Roli Roberts (@RoliRoberts) profile picture
Roli Roberts@RoliRoberts21 Nov 2023
What's your favourite #protist? Magnificent protist image resource from Yana Eglit & @pjkeelinglab just out in @PLOSBiology journals.plos.org/plosbiolog…
Image from Roli Roberts (@RoliRoberts)
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The Institut Jacques Monod is recruiting new group leaders. Please spread the word and/or apply to be our neighbor! Don’t hesitate to contact me if you want more information.
Institut Jacques Monod (@IJMonod) profile pictureInstitut Jacques Monod@IJMonod14 Nov 2023
❗️Call for Group Leaders❗️ The @IJMonod, a leading center for fundamental interdisciplinary research in biology, is seeking to appoint at least two new group leaders. ➡️ijm.fr/?lang=en Apply before February 16th 2024 Application form➡️urlz.fr/ordV
Image from Institut Jacques Monod (@IJMonod)
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Check out our primer on a great paper by @MfPez & @PSarkies uncovering histones as methylation sinks in human cells. Histone methylation reflects cellular methylation potential independently of gene reg. Time to consider chromatin a metabolic organelle 1/3 journals.plos.org/plosbiolog…
Metabolic sinkholes: Histones as methyl repositories

Metabolic sinkholes: Histones as methyl repositories

Perez and Sarkies uncover histones as methyl group repositories in normal and cancer human cells, shedding light on an intriguing function of histone methylation in optimizing the cellular methylat...

journals.plos.org
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DuharcourtLab retweeted
EMBL Events (@EMBLEvents) profile picture
EMBL Events
@EMBLEvents23 Oct 2023
Transposable elements (TEs) are major drivers of genetic diversity and contribute to human disease. Want to know more? You are still on time to attend #EMBOMobileGenome virtually💻🙌. Don't miss your chance! 🛎️Register by 1 November ➡️s.embl.org/mge23-01
Image from EMBL Events (@EMBLEvents)
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⛵️Voici une image des six matelots de l'@IJMonod en route pour leur course de nuit du GLAZ avec le déploiement du SPI gonflé ⚓️
Image from Institut Jacques Monod (@IJMonod)
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