Thomas Balan (@Thomas_Balann) header
Thomas Balan (@Thomas_Balann) profile picture

Thomas Balan

@Thomas_Balann

PhD student @DuharcourtLab Sudying developmentally programmed genome rearrangments in Paramecium #Paramecium #TEs #Histones (https://nitter.gq/t.co/AgDO0Vl0cX)

 Paris, France
Joined September 2013
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Very happy to share my first review! We explore the unique similarities and differences between ciliates and other eukaryotes regarding small-RNA-directed chromatin silencing.
DuharcourtLab (@DuharcourtLab) profile pictureDuharcourtLab@DuharcourtLab15 Apr 2024
Happy to share our review dx.doi.org/10.1002/wrna.1848 we highlight the similarities and differences between ciliates and other eukaryotes in small-RNA-directed chromatin silencing. @IJMonod @CNRSbiologie @toma_bln @DannyHoloch
Small‐RNA‐guided histone modifications and somatic genome elimination in ciliates

Small‐RNA‐guided histone modifications and somatic genome elimination in ciliates

In ciliates, an ancestral pathway for transposable element repression by small RNAs and histone methyltransferases has evolved into a highly orchestrated process to eliminate unwanted sequences from...

wires.onlinelibrary.wiley.com
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❗️Institut Jacques Monod Seminars❗️ Tomorrow, Till Bartke will give an Institut Jacques Monod Seminars on the theme "Decoding chromatin states by proteomic profiling of modification-dependent nucleosome readers" ➡️urls.fr/aFo0u8 @CNRS_Villejuif @univ_paris_cite
Image from Institut Jacques Monod (@IJMonod)
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⚓️The departure of the last race was pretty tough, but thanks to the great tactics abilities of their captain @Thomas_Balann our youngest crew ended up 7/19 in the final ranking!
Image from Institut Jacques Monod (@IJMonod)
Image from Institut Jacques Monod (@IJMonod)
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Congratulations Thomas! #ProudPI
PeerJ Publishing (@thePeerJ) profile picturePeerJ Publishing@thePeerJ6 Jun 2024
PeerJ congratulates Thomas Balan (@Thomas_Balann) and Clément Goubert (@clementgoubert) award winners at ICTE 2024 (@ICTE2024) Learn more about their research on the PeerJ blog bit.ly/4ecaIxz #Transposableelements #mobileDNA #DNA @clementgoubert
Image from PeerJ Publishing (@thePeerJ)
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Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
Image from Demis Hassabis (@demishassabis)
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Glad to announce the publication in @NatureComms of our study rdcu.be/dFBcE by Pierre Romero & Laia Richart in Raphaël Margueron’s lab at @institut_curie on the molecular consequences of EZH2 mutations found in non-Hodgkin lymphoma. (1/3)
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So honored of this! Amazing discussions at #ICTE2024 during the poster sessions! Already looking forward to the next edition !
International congress on transposable elements (@ICTE2024) profile pictureInternational congress on transposable elements@ICTE202423 Apr 2024
#ICTE2024 congrats to the three poster winners: @clementgoubert , @toma_bln and Victor Billon!
Image from International congress on transposable elements (@ICTE2024)
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#ICTE2024 congrats to the three poster winners: @clementgoubert , @toma_bln and Victor Billon!
Image from International congress on transposable elements (@ICTE2024)
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Thomas Balan retweeted
Roman Barth (@RomanBarth2) profile picture
Roman Barth@RomanBarth224 Mar 2024
Today on @biorxivpreprint 📜: SMCs WITH A TWIST 🌀 Back-to-back with Iain Davidson, Jan-Michael Peters et al., @IMPvienna we uncovered a phenomenon shared by all eukaryotic SMC proteins: they twist DNA during loop extrusion. Buckle up, we have a lot to walk you through… 🧵 1/
Image from Roman Barth (@RomanBarth2)
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Excited to see our paper "Decoding Chromatin States by Proteomic Profiling of Nucleosome Readers" out in @Nature! rdcu.be/dAv5S Explore our data on how epigenetic modifications modulate protein binding to chromatin with MARCS marcs.helmholtz-munich.de/ Details below 👇
Image from Andrey Tvardovskiy (@ATvardovskiy)
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#JobOffer 💼Ingénieur d'études en biologie moléculaire (H/F) 📍@DuharcourtLab 🗓️ 22 janvier 2024 Candidatez avant le 28 décembre➡️emploi.cnrs.fr/Offres/CDD/UM…
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⛵️Notre équipage a décroché la 7e place (sur 17) et a été décoré du prix de courtoisie pour avoir remoqué un bateau en détresse lors de la course de nuit !⚓️
Image from Institut Jacques Monod (@IJMonod)
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⛵️Voici une image des six matelots de l'@IJMonod en route pour leur course de nuit du GLAZ avec le déploiement du SPI gonflé ⚓️
Image from Institut Jacques Monod (@IJMonod)
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Special thanks to Canceropole CLARA @canceropoleCLARA for sponsoring Poster Prizes ! ▶️ @CharmantOlivia from @DuharcourtLab ▶️ @PNgsabrina ▶️ Ivona Biocanin from Barneche lab
Image from Jérôme Govin (@JeromeGovin)
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Captivating discussions during the poster session at #Epi_Gre2023 !
EMBL Grenoble (@EMBLGrenoble) profile pictureEMBL Grenoble@EMBLGrenoble3 Oct 2023
#Epi_Gre2023 Day 1 recap Shelley Berger from the University of Pennsylvania gave a keynote talk to initiate the sessions on epigenetics complexes & on the Chromatin / nuclear structure and RNA. Then participants gathered for the traditional poster sessions! Enjoy Day 2!
Image from EMBL Grenoble (@EMBLGrenoble)
Image from EMBL Grenoble (@EMBLGrenoble)
Image from EMBL Grenoble (@EMBLGrenoble)
Image from EMBL Grenoble (@EMBLGrenoble)
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🚨Cool new preprint from the lab! Congrats @CharmantOlivia 🎉
DuharcourtLab (@DuharcourtLab) profile pictureDuharcourtLab@DuharcourtLab20 Sep 2023
Preprint alert. We’re thrilled to announce the latest work from our lab: The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium. A thread with our key findings: (1/6) biorxiv.org/content/10.1101/…
The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in...

The nuclear PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in...

Ciliates undergo developmentally programmed genome elimination, in which small RNAs direct the removal of target DNA segments, including transposable elements. At each sexual generation, the develo...

biorxiv.org
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#SaveTheDate 📅 21 septembre à 14h 📍 Salle François Jacob @CharmantOlivia (équipe de @DuharcourtLab ) présentera sa soutenance de thèse "Elimination programmée d'ADN chez Paramecium tetraurelia : caractérisation de protéines contrôlant la dynamique des petits ARN".
Image from Institut Jacques Monod (@IJMonod)
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#joboffer Ingénieur en biologie moléculaire (H/F) 📅 1er janvier 2024 📍@DuharcourtLab, Institut Jacques Monod, Paris ➡️ijm.fr/recherche/duharcourt-… Candidatez sur emploi.cnrs.fr/Offres/CDD/UM… avant le 18 septembre
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#SaveTheDate 🗓️ September 15th Invited by the @DuharcourtLab, Peter Sarkies (@PSarkies) will give an IJM seminar entitled "Using evolution to understand epigenetic mechanisms" ➡️ijm.fr/ijm-seminar-peter-sar… @CNRS_Villejuif @univ_paris_cite
Image from Institut Jacques Monod (@IJMonod)
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Very glad to share our preprint: Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium biorxiv.org/content/10.1101/…. Feedback and comments are welcome !
Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome...

Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome...

To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, bind to...

biorxiv.org
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