Man of Science 🧬 AI & Gerophysics to understand Aging. 🇸🇬 Rethinking the Fundamentals of Aging & Rejuvenation Biology @TTIScience 🇺🇸
Singapore & Europe
Joined October 2018
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Very short but on point summary of some recent talks I gave on maximum lifespan, comparative biology, and biomedical mega projects!
To find why some mammals live many times longer than others, @MaxUnfried of @TTIScience proposes a shared freezer bank of tissue from about 200 species, young to old, all stored and measured the same way, so lab quirks stop passing for biology. For now it is a plan.
Max Unfried retweeted
To find why some mammals live many times longer than others, @MaxUnfried of @TTIScience proposes a shared freezer bank of tissue from about 200 species, young to old, all stored and measured the same way, so lab quirks stop passing for biology. For now it is a plan.
Max Unfried retweeted
The pain and suffering and massive expense of the litigation was worth it not only for vindication by a jury of my peers but also to reveal exactly how scientific institutions decided not to follow due process (which is almost akin to scientific method)
MIT thinks it can put on a show claiming to value merit to keep the DOJ and the White House off its back.
David Sabatini’s case exposes that smokescreen. Their true colors were on display throughout his ordeal. Scientific excellence was disposable when it conflicted with their political priorities. They have hollowed out the science while continuing to trade on the reputation it built. Their real priorities are far removed from the excellence they advertise.
Excellent article from @mrddmia.
foxnews.com/opinion/mike-dav…
Pretty horrible judgment by university leadership.
Troubling evidence revealed in Sabatini case at @mit
Kristin Knouse messaged that Sabatini was going to be "Weinstein’ed out of science"; that she was "out for blood"
University administration ran an investigation which had a predetermined outcome
foxnews.com/opinion/mike-dav…
Max Unfried retweeted
Tomorrow at 11:30 AM PT join @VadimGladyshev @gladyshev_lab, a leader in the science of aging, and me, for a conversation on biomarkers, clocks, rejuvenation, AI, and where the field is headed
open.substack.com/live-strea…
Max Unfried retweeted
Am I missing something?
Where do the inputs to train this simulation come from? Compute is not the bottleneck in biology.
It’s estimated we have only sequenced genomes for 1% of eukaryotic species, and DNA is just the beginning.
Infinite compute can’t help you simulate a system that’s never even been observed or measured.
If you had an exponential amount of compute you could solve simulate biology exactly and wouldn't need to run any experiments.
Some of you will think "of course, but that's an unrealistic assumption" and others will think "no, you need experiments even with that much compute. That's just How It's Done".
You would of course need evaluations once you have a solution, but you don't in principle need experiments to find it: Experiments are a way to save compute, dating from a time when it was much more expensive.
And I think the presentation is exponential but real systems aren't irreducibly exponential. AlphaFold worked, after all.
Erst kamen sie fĂĽr die Synagogen.
Dann fĂĽr die Kirchen.
And zuletzt für die Universitäten.
Would be cool to see that Roman Catholic Religious Orders like the Teutonic Order, the Equestrian Order of the Holy Sepulchre, or the Sovereign Military Order of Malta take an active interest in longevity science and medicine.
Hinton got it wrong.
It’s actually okay if it has the desire and wants to kill you.
It just must not be able to kill you.
In the case of the tiger this means chaining it, pulling its teeth, and taking off its claws.
Max Unfried retweeted
I’m convinced 95% of being a high performer is to just do 5 things:
- Be obsessed like a psychopath
- Have delusional optimism
- Avoid unserious people
- Take asymmetric risks
- Be relentless
Hope we will also get war mammoths to secure land border, and war whales to secure sea borders.
JUST IN: Palmer Luckey's genetically modified military dog startup, Warhound, comes out of stealth, aiming to create enhanced canines for the U.S. military.
Readers added context they thought people might want to know
This is NOT Palmer's company at all, his company Anduril is only supplying the tech for the dogs, and this is a wholly owed Collosal entiity
x.com/palmerluckey/s…
It’s a great day for science without boundary.
At any given time in civilizational history we should fully lean into what science is capable in accomplishing.
The markets then will price it accordingly and and see if it’s wanted.
Colossal Biosciences’ founder has started a new venture to create new bio-enhanced military dogs in collaboration with Anduril’s Palmer Luckey forbes.com/sites/amyfeldman/…
Max Unfried retweeted
Fantastic Junior Group leader position at the Curie Institute in Paris!! Areas of interest include stem cells, tissue growth and morphogenesis, epigenetics, genomics, integrated physiology, metabolism, and synthetic embryo models. Please RT!
jpi-recruitment-curie-umr321…
Enhanced animals are a pretty good start to get to enhanced humans.
JUST IN: Palmer Luckey's genetically modified military dog startup, Warhound, comes out of stealth, aiming to create enhanced canines for the U.S. military.
Readers added context they thought people might want to know
This is NOT Palmer's company at all, his company Anduril is only supplying the tech for the dogs, and this is a wholly owed Collosal entiity
x.com/palmerluckey/s…
If you're in town worth checking out if you're interested in longevity and jurisdictions that try to accelerate progress!
If you're in Singapore and want to learn about Montana's new Right to Try program, I'll be hosting an event on October 26th!
luma.com/infinita-singapore
Max Unfried retweeted
One codon-level therapy can hit nonsense mutations shared across multiple aging diseases. Brian Bodemann (ARTAN Bio) at #ARDD2026. Photos: agingpharma.org/photos2026
Really wish caning 🦯 would be part of the sentence.
BREAKING:
The first rioters and looters have been sentenced in France.
The judges practically refuse to hand out prison sentences:
🔴 Toulouse – Ylan, 18 years old. Throwing a Molotov cocktail at police officer
- Sentence: 12 months suspended + 140 hours of community service + deprivation of voting rights for 3 years.
- Max. sentence: 10 years in prison
🔴 Lille – 3 men, including 2 illegal migrants. Arrested with bags filled with loot from Micromania and Calzedonia stores.
- Sentence: 10 months in prison with custody warrant + 2-year territorial ban (for the 2 undocumented migrants).
- Max. sentence: 5 years
🔴 Lille – Father of a family with a crowbar, attempted break-in at a store.
- Sentence: 10 months in prison with custody warrant + 3-year ban on demonstrations.
- Max. sentence: 7 years
🔴 Lille – 23-year-old man, launching fireworks at police
- Sentence: 12 months under electronic monitoring + 140 hours of community service.
- Max. sentence: 5 years
🔴 Reims – Sahel W., 19 years old. Looting a Carrefour
- Sentence: 105 hours of community service.
- Max. sentence: 7 years
🔴 Reims – Hugo M., 20 years old. Looting a Caviar boutique.
- Sentence: 4 months under electronic monitoring.
- Max. sentence: 7 years.
🔴 Rouen – Tunisian delivery driver, looting of a gold buyback shop (16,000€ worth of jewelry in his pockets). Repeat offender.
- Sentence: 8 months in prison with custody warrant + revocation of 6 months suspended from a previous conviction.
- Max. sentence: 14 years
🔴 Rouen – Anthony, homeless. Looting of the Courir boutique. Repeat offender.
- Sentence: 6 months in prison + 6 suspended.
- Max. sentence: 14 years
🔴 Rouen – 26-year-old unemployed man. Looting of Micromania. Repeat offender.
- Sentence: 6 months under electronic monitoring.
- Max. sentence: 14 years
🔴 Rouen – Nicolas, garbage collector, and Zakaria. Throwing projectiles at police and insults.
- Sentence: 12 months under electronic monitoring.
- Max. sentence: 5 years
🔴 Lyon – Mohamed, illegal migrant. Looting of Louis Vuitton boutique (6 wallets, 2 pairs of glasses, one pair of pants, one leather bag, and one fabric bag).
- Sentence: 6 months in prison with custody warrant
- Max. sentence: 7 years
🔴 Lyon – Cheima, 30-year-old woman. Looting of JD Sports store
- Sentence: 8 months suspended.
- Max. sentence: 7 years
🔴 Lyon – Sophia, 27 years old. Already 9 convictions including thefts. Looting of JD Sports store.
- Sentence: 12 months under electronic monitoring.
- Max. sentence: 14 years
🔴 Lyon – Adam, 19-y-old Swiss national. "Black bloc" from abroad. Arrested leaving a looted Monoprix + resistance
- Sentence: 12 months suspended.
- Max. sentence: 7 years
🔴 Perpignan – 20-y-old man, throwing a construction barrier at 2 police officers.
- Sentence: 6 months under electronic monitoring
- Max. sentence: 5 years
🔴 Perpignan – 21-y-old man. Throwing objects at police and vandalizing the city. Ski goggles, t-shirt as balaclava, and reinforced gloves.
- Sentence: 10 months under electronic monitoring.
- Max. sentence: 7 years
🔴 Perpignan – 22-y-old Amazon delivery driver, already one prior conviction. Scooter theft after demonstration with face concealment, in a group and break-in
- Sentence: 8 months under electronic monitoring.
- Max. sentence: 10 years
🔴 Limoges – 20-y-old woman. Looting in stores and at City Hall (later destroyed by fire)
- Sentence: 6 months in prison with custody warrant + 18 suspended prob.
- Max. sentence: 12 years
🔴 Pau – 43-y-old man. Throwing objects at police
- Sentence: 6 months under electronic monitoring.
- Max. sentence: 5 years
🔴 Nîmes – 24-y-old PE teacher. Throwing objects that injured a police man (3 days of leave).
- Sentence: 18 months suspended prob.
- Max. sentence: 5 years
🔴 Grenoble – 10 people. Looting
Sentences: from 4 months suspended to 8 months served (served for 1 individual already convicted to suspended in June).
Max. sentence: 7 years
