OWL retweeted
A security guard turned $900 into $187,000 on Polymarket.
Guarded empty buildings for 10 years at $16/hour.
One sleepless shift he built a BTC bot with Claude Opus 4.8.
Never wrote a single line of code.
I found his wallet. Reverse-engineered the entire system.
Here is what he actually did.
Gave Claude new Fable 5 two prompts at the start of his shift.
Opus did not write the bot.
It drew the blueprint: data, signals, backtest, risk, execution.
Then handed that blueprint to a swarm of 300 agents.
How it works:
→ Decompose: Claude Fable 5 breaks the goal into a task tree
→ Dispatch: 300 agents fan out (some pulling Binance data, some writing code, some backtesting 5 years of data)
→ Execute: 4,000 steps in one 14-hour run
→ Review: Claude Fable 5 reads it all back and kills whatever drifted
The brain never wrote a line.
The hands never made a call.
By sunrise he had what a 6-engineer quant team ships in a quarter.
A live BTC bot on Polymarket. Backtested. Risk-capped. Running 24/7.
For 10 years he watched empty buildings.
Now 300 agents watch the market while he sleeps.
I rebuilt this exact system with Claude new Fable 5
You only need Claude + device + 1 hour to deploy.
Giving this free for 24 hours.
To get it:
1. Comment "Claude"
2. Like and retweet this
3. Follow me @codewithimanshu so I can DM you
OWL retweeted
Here's the paper itself. If you're interested in joining the team to turn this into a medicine, please reach out science.org/doi/10.1126/scie…
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Scientific research is broken.🧪
@erinmagennis , co-founder of @MuseMatrix_ , explains the funding game is monopolised by governments & legacy institutions. 🏰
DeSci flips the model - decentralizing participation, funding & access to research.
👉This is part 1 of our @erinmagennis voices of web3 interview.
Follow @ChainRctnGlobal to learn more.
🎥Shot by @samiwanczak
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NEW PAPER: Partial reprogramming with virally-delivered OSK genes rejuvenates senescent cells, restores tissue integrity, heals wounds & extends lifespan in mice. Can't wait to see if it works in humans @lifebiosciences 🚀 tinyurl.com/mutfbtbw
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Accelerate permissionless science on Solana 🧪
Big shoutout to everyone who joined us at the DeSci Fair in NYC!
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Join us for a chat about funding novel science using preregistrations on @ResearchHub
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New research I’d like to highlight this week—covering Alzheimer’s disease, brain vasculature, spinal cord injury, stem cells and more!
Earn $150 by reviewing any of these papers on @ResearchHub @ResearchHubF
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The CRISPR companies are not OK.
This morning my colleague @Jasonmmast published a tour de force on the gene-editing technology that was expected to change the world. It still might!
But right now, to rewrite My Chemical Romance:
"Despite giant funding rounds/ These companies have run aground/ Remember when you got approved then had layoffs?"
They're not OK.
OWL retweeted
2024's top 10 advances in biology (🧵)
1. Progress in longevity
Blocking the pro-inflammatory cytokine, IL11, extended healthspan and lifespan (in mice!)
Old mice without IL11 look healthier, they're stronger, and they live longer
nature.com/articles/s41586-0…
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How DeSci Revolutionises Funding nitter.gq/i/broadcasts/1gqxvNnam…
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Earlier this year, generative AI was used to make completely new antibodies for the first time
nature.com/articles/d41586-0…
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A bottom-up approach to revolutionary biomedical science
The financial rails are forming 🧬
@sebastian_gero x @paulkhls
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🚀 Dive into the journey of innovation with @MarkKotter, Founder and CEO at @bitbio! Discover how they’re revolutionizing biology to democratize human cell access and therapies. 🌟 #Biotech #Innovation
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Julian Assange landed in Australia for the first time in more than a decade, after a guilty plea in a US court allowed him to return to his home country a free man trib.al/uvXICmi
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Replying to @BioProtocol @bio_xyz
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Join us 𝗧𝗢𝗗𝗔𝗬 at 4pm UTC for Accelerating DeSci - our live roundtable for bioheads 🦠
⦿ What the f*ck is bio/acc? ( @paulkhls )
⦿ BIO protocol, $BIO airdrop & DeSci stats ( @KibaGateaux )
⦿ $VITARNA sale ( @vita_dao crew )
🔔 Set a reminder 👇 nitter.gq/i/spaces/1OdKrjBdkjpKX
OWL retweeted
If you’ve been following me, you know that I’ve been doing video interviews with biotech leaders on social media for years. Now I’m taking it to the next level.
Launching today:
BiotechTV.com @BiotechTVHQ
OWL retweeted
Our genomes are littered with *junk* DNA known as LINE retrotransposons, which are powerful enzymes that can insert DNA into the genome. We are excited to report the structure of the LINE family member R2 and ways to engineer it for programmable gene insertion. Congratulations to @maxewilkinson, @FrangiehChris, RMacrae! @ScienceMagazine science.org/doi/10.1126/scie…
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Tweeps, does anyone have a good suggestion for an N-cadherin antibody? Or a cadherin IF protocol tip that is going to solve all of our problems?
We got one from @CellSignal (whom we trust) but the IF staining in our cells (which should express it based on RNA) looks funny.




























