Kozo Tomita Lab: RNA Biology

The wait ⏰ is over! Most structure prediction tools give you 1 answer. #RNA just doesn’t work that way - it's the ultimate shapeshifter. Today, we’re launching #RNAccess by Emergente Inc. with access for academic, nonprofit, and commercial researchers. RNAccess is powered by #RNAnneal, our physics-grounded #AI engine for #RNA structure prediction. By combining physics-based simulation with Generative AI, RNAnneal captures the structural flexibility that makes RNA both incredibly challenging—and incredibly powerful. The workflow is simple: 🧬Submit an RNA sequence of up to 100 nucleotides (long RNAs coming soon). ⚡Receive a thermodynamically ranked ensemble of high-accuracy 3D structures. 🔍Explore results through intuitive, interactive visualizations in your browser. 🦠Example: A key functional region of SARS-CoV-2 #RNA pictured below was predicted + visualized accurately in #RNAccess (with no prior knowledge, just physics!) We built #RNAccess to make serious RNA structure prediction more accurate, accessible, and useful for researchers working across all RNA work, from fundamental discovery to applied innovations. No local compute. No pipeline setup. No coding experience needed. Not even a GPU bill - we’ve got that covered 🙇 🎓Academic/non-commercial researchers: Receive a free batch of predictions every month, with pay-as-you-go options when you need more. 🏢Commercial teams: Start with a complimentary prediction, then talk with us about evaluation, confidential use, and larger-scale applications. 📍Try RNAccess: emergente-sci.com 📍Contact: [email protected] Come fold with us 💫 ------------------ It took a village to get this far. Thank you to @NIH-NIGMS, @NSF -Chemistry-CTMC, TEDCO, University of Maryland Institute for Health Computing, Institute for Physical Science and Technology, Montgomery County Government, UMD Chemistry and Biochemistry, @UMDscience, @UMmedschool and many others for financial and other support. Gratitude to leadership Bradley Maron, MD, Adam Porter, @VarshneyAmitabh, Mark T. Gladwin, MD, Martha Jurczak for their continued faith in our team at University of Maryland Institute for Health Computing and in Emergente Inc. - the first startup out of the IHC! And finally, huge thanks to our awesome scientific advisers Robert Copeland, Jonathan Dinman and John (Jay) Schneekloth for their guidance.