DrayLab (@dray_lab) profile picture

We're the Dray lab. We like chromosomes and study DNA repair and recombination at UTHSCSA. Tweets are a group effort, sharing science we like.

San Antonio, TX
Joined March 2018
Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)Photo by DrayLab (@dray_lab)
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @plantsci jobs.cam.ac.uk/job/51488/
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Just published📢 Our new forum article on Fc-optimized checkpoint antibodies for cancer therapy. New to immunotherapy and antibody engineering? This one’s for you! Co-authored with Alan Korman. @TrendsMolecMed #CancerImmunotherapy #FcEngineering sciencedirect.com/science/ar…
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Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov/
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#1 Happy to share our work “Specialized replication mechanisms maintain genome stability at human centromeres” @MolecularCell from A. Scelfo, A. Angrisani and T. Wilhelm @institut_curie @CNRS where we provide the causes of centromere fragility. authors.elsevier.com/a/1iba6…
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There's actually some difference
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📢📢 Applications are now open for 2024 @ForbeckForums Scholars! If you are interested in genomic instability in cancer, please consider applying to attend our upcoming meeting as a Scholar. We have a fantastic line-up of speakers so far. Details here: forbeckforums.org/scholar-aw…
We are organizing a @ForbeckForums on Cancer Genome Rearrangements next year in Aspen, Colorado. If you are a senior postdoc or early-career PI, I strongly encourage you to apply to become a Forbeck Scholar. A call for applications will be announced soon. forbeckforums.org/forums/mec…
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Why @FASEBorg???? No recordings, no photo policy allowed presentation of hot, new, unpublished data and vigorous discussions... Your new policy ruins it. Also, you collect exuberant registration fees from us and then you want rights to our "content"? Doesn't make sense!
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New paper in @MolecularCell! Loss of EXO1-dependent SSA is a vulnerability of BRCA1-deficient cells. Great work by @BertKooij, Anne Schreuder, @pavani_raphael in collaboration with @cuppen, @luijsterburglab, @marcelvanvugt, @nussenza, @SylvieNoorderm1. tinyurl.com/2sdkz3j2
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We have received a lot of requests for help with making streptavidin affinity grids. We are happy to finally share our protocol for robust in-house fabrication of streptavidin affinity grids. Stay tuned for the accompanying video that is coming soon! app.jove.com/t/66197/strepta…
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DrayLab retweeted
Do cells care if their mitochondrial DNA is broken? Yes! Excited to share my PhD work showing that a fraction of cells with breaks in their mtDNA recover healthy mitochondria using the integrated stress response.
Online Now: Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis dlvr.it/SxMgD3
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We are searching for a highly-motivated postdoc to study a newly-identified DNA repair protein, ZNF384, using state of the art functional genomics and biochemistry approaches. Interested in joining vanattikumlab.org? Apply via the link below: tinyurl.com/hedwn8nx
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Check out our new paper by the extremely talented postdoc @James__Cornwell out now in @Nature. For decades it was thought the cell cycle was irreversible, but now we show that is not the case. nature.com/articles/s41586-0…
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It is a great pleasure to share our recent publication demonstrating that circulating microRNAs may be used to identify BRCA1/2 mutations in patients of high risk of cancer, offering an opportunity to reduce screening costs. #earlydetection #microRNAs nature.com/articles/s41467-0… – at Boston, MA
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A breakthrough in DNA repair research! @SimonBoulton and @StephenWest at @TheCrick has used #C-Trap technology to explore the BCDX2 complex. This could lead to new therapeutic strategies for diseases linked to RAD51 paralog complex mutations. Check here: go.nature.com/3PoCTzC
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Remember that kid you gave a “C” to in your state politics course? He is now in the state legislature and is about to end tenure.
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Hidden in plain sight, and now revealed! Alternative translational protein isoforms help explain how cells create a mitotic arrest timer. It was amazing to live vicariously through these unexpected discoveries from Cheese lab post-doc Mary Jane Tsang. wi.mit.edu/news/protein-hidd…
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Excited to share our work in @JCellBiol describing a new function for the E3 ubiquitin ligase RFWD3 (FANCW) in the regulation of replication fork remodeling. Terrific collaboration with Vincenzo Costanzo (temporarily twitterless) and @CicciaAlberto! (1/5) doi.org/10.1083/jcb.20210602…
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