Robert Buder

Your patient in the ED on [insert Xa-inhibitor drug] has an ICH on brain CT. Do you: (A) give them a drug (andexanet) that costs (someone) an arm and a leg that reduces hematoma expansion without any difference in functional outcome and increases (doubles) thrombotic events, or (B) keep doing the same thing you've been doing The ANNEXA-I study was published yesterday and found exactly that - no patient-centered benefit but evidence of harm. IOW, just keep doing your usual thing for now. nejm.org/doi/full/10.1056/NE… #emergency #emergencymedicine #criticalcare #icu #erlife #iculife #science #research #data #army #armymedicine #armyemdoc #trauma #tbi #brain #medx #medtwitter

Does VL improve first-pass success over DL in the operating room? In this well designed RCT, they found similar findings as our #DEVICE trial with superiority of VL. This trial also stopped early due to efficacy. In particular, they specified hyperangulated blades. FPS was 98.3% in the HAVL group versus 92.4% in the DL group. jamanetwork.com/journals/jam… #emergency #emergencymedicine #foam #foamed #foamcc #army #armymedicine #armyemdoc #meded #icu #criticalcare #anesthesia #anesthesiologist #crna #airway #medairway #airwaytwitter #medx #medairwaytwitter