
I am a pharmacist doing research to cure sarcoma @srgidibell and now also entrepreneur, founder of Aptadel therapeutics @aptadel. Also a runner
Esplugues de Llob, Catalunya
Joined August 2011
- Tweets4K
- Following1K
- Followers684
- Likes5.8K
Pinned Tweet
Marathons run:
1997 San Sebastian 2h52’
2000 Barcelona 2h38’
2003 Marine Corp’s DC 2h45’
2020 El Prat 3h17’
2021 Barcelona 3h08’
2022 UltraPirineu 8h00’
2023 Athens 3h28’
2024 San Sebastian Cancelled
2025 Rome 3h33’
2026 Edimburg 3h43’
Next Copenhagen 2027
Oscar Martinez retweeted
BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
I have to post this, I sent our work to publish back in January 21st this year to @oncogenejournal today 181 days after, still waiting first decision. I talked to the editor and the answer was they are having trouble getting reviewers. ASK WHY!!! Meanwhile two grant rejections….
I don’t mean this is the reason, but helps. Journals need to think about rewarding reviewers with money not gifts in form of free submissions… Humble labs are dying and in no time @SRGIDIBELL will be one of them @ASEICAnews @idibell_cat
Marathons run:
1997 San Sebastian 2h52’
2000 Barcelona 2h38’
2003 Marine Corp’s DC 2h45’
2020 El Prat 3h17’
2021 Barcelona 3h08’
2022 UltraPirineu 8h00’
2023 Athens 3h28’
2024 San Sebastian Cancelled
2025 Rome 3h33’
2026 Edimburg 3h43’
Next….
Oscar Martinez retweeted
🔬 Impulsar innovación es acompañar la investigación hasta el paciente.
Llevamos más de 10 años apoyando al Dr. Òscar Martínez-Tirado @SRGIDIBELL en el @idibell_cat en una estrategia innovadora frente al Sarcoma De Ewing.
Más info 👇
blog.contraelcancer.es/inves… 💚
Aptadel Therapeutics capta 2 M€ per desenvolupar el seu fàrmac contra el sarcoma d'Ewing ara.cat/economia/farmaceutiq…
Oscar Martinez retweeted
Ponència “Innovació: del laboratori al pacient” Participen: STAb Therapeutics, Belén Blanco; STAb Therapeutics, Elena Barba; IDIBELL, Òscar Martínez-Tirado; Aptadel Therapeutics, Gisela Llorente. La recerca es transforma en solucions reals per a les persones #contraelcancerbcn
Oscar Martinez retweeted
60 ajudes. 13,11M€ el 2025. 68,62M€ en desenvolupament a Barcelona. La supervivència depèn de la recerca. Seguim! #contraelcancerbcn
Oscar Martinez retweeted
A new paper reveals that adhesion GPCRs promote extracellular vesicle (EV) formation and EVs spread GPCRs into neighboring cells to activate G-protein signaling, providing a novel mechanism for cell-cell communication
nature.com/articles/s41589-0…
Oscar Martinez retweeted
Esto es magnifico, pero un plan para aumentar el raquítico presupuesto actual sería de gran ayuda para todos los científicos
✅ El Gobierno aprueba una declaración institucional con motivo del #DíaMujerYNiñaEnCiencia, para “avanzar hacia un sistema científico basado en la igualdad de oportunidades y en el aprovechamiento pleno del talento”.
ciencia.gob.es/Noticias/2026…
Oscar Martinez retweeted
In preclinical models of neuroblastoma, SCLC, and colorectal cancer, we observe reduced tumor growth, improved survival, and signs of ICD.
Link:link.springer.com/article/10…
@CNIOStopCancer @BioInn_CIEMAT @SpringerNature @BioMedCentral
Oscar Martinez retweeted
Now that everyone is an expert on curing pancreatic cancer in mice, not rats - I want to add some context that goes beyond the headline.
You will want to read this.
Cancer is cured in mice all the time.
Thousands of times. ~90% of those “cures” fail in humans.
Why?
Because mice are:
Genetically simpler.
Treated earlier.
Short-lived.
Not humans.
Mice are a filter - not a finish line.
Yes, this study matters. It comes from the Spanish National Cancer Research Centre.
Yes, it’s pancreatic cancer - one of the deadliest there is. Yes, full tumor regression is impressive.
But here’s what it actually means:
“This approach is now good enough to risk years, trials, and millions of euros on.”
Not:
“Cancer is solved.”
What happens next?
More animal work.
Toxicology.
Phase I (safety).
Phase II (maybe works).
Phase III (beats standard care?).
Maybe 8-10 years if everything goes right.
The real damage isn’t failed drugs.
It’s failed expectations.
Every “cured cancer in mice” headline trains the public to believe:
Cures are being hidden.
Progress should be fast.
Scientists are lying when reality hits.
That’s how trust erodes.
Bottom line:
This is how real cancer progress looks.
Messy. Slow. Risky. Incremental.
Not miracles.
Not conspiracies.
Just science - doing the hard work.
Oh my!
AlphaGenome is out in @nature today along with model weights! 🧬
📄 Paper: nature.com/articles/s41586-0…
💻 Weights: github.com/google-deepmind/a…
Getting here wasn’t a straight path. We sat down @googledeepmind to discuss the story behind the model, paper & API: youtu.be/V8lhUqKqzUc
Oscar Martinez retweeted
The Viladecans Association Against Cancer allocates the money raised in 2025 to research against colorectal cancer🙌🤍
Since 2016, the Association has collected +200,000€ for IDIBELL's research: a real driving force. Thank you very much!
👉idibell.cat/en/2026/01/the-v…
Oscar Martinez retweeted
🧬 Cell therapy in #sarcoma: what do we know so far?
In our review in @jitcancer we cover
✔️TCR-T, CAR-T, TIL, NK-cell approaches
✔️Early clinical studies
✔️Key biological & practical challenges, inc. the tumour microenvironment
✔️Emerging directions
🔗 jitc.bmj.com/content/14/1/e0…
To end the year I’d like to share our last work, comments are welcome. Many thanks to all the magnificent researchers involved! biorxiv.org/content/10.64898…
Oscar Martinez retweeted
From all of us at Ensembl, we wish you holidays filled with "ATGGAACGCCGCATTATGGAAAACACCGCGAACGATCCGGAAGCGTGCGAA"
May your celebrations be as perfectly in‑frame as your favourite gene.
Oscar Martinez retweeted
🔥 Your entire immune system starts with one cell.
Every red blood cell that carries oxygen
Every platelet that stops a cut from bleeding
Every neutrophil that attacks bacteria
Every T cell that hunts viruses
Every B cell that makes antibodies
All of them come from the same origin: a single pluripotent hematopoietic stem cell hidden inside your bone marrow.
🩸 What this stem cell can become
With the right signals from molecules like IL-3, GM-CSF, IL-7, SCF, and others, this stem cell divides and chooses a path:
• Red blood cells to deliver oxygen
• Platelets to form clots
• Neutrophils, eosinophils, and basophils to fight infection
• Monocytes and macrophages to clean up dead cells and debris
• B cells that produce IgG, IgA, IgM, and other antibodies
• T cells that orchestrate your immune defense
• Natural killer cells that recognize and destroy infected or malignant cells
Every branch in the diagram is a decision point based on the chemical signals surrounding the cell.
🧪 Why this matters
Your energy, your immunity, your ability to heal, and your resistance to infection depend on how well this system works.
When hematopoiesis is disrupted, it can lead to:
• anemia
• weakened immunity
• autoimmune problems
• slow healing
• susceptibility to infections
• blood cancers
Healthy blood begins with healthy stem cell signaling.
Inside your bone marrow, millions of stem cells are working every minute to build your immune system from scratch.
It is one of the most complex and elegant engineering systems in the human body.


























