
@Stripe CEO, @ArcInstitute cofounder.
Joined April 2007
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Tyler and I just published a list of the recipients of the New Aesthetics grants: newaesthetics.art/grants.
Thank you very much to all who applied. There were far more applications than we expected. We funded 28 grantees and are excited to see what they create.
My reflections on the whole thing:
• Though there are clearly selection dynamics afoot, figuring out some route beyond the current aesthetic moment seems to be of wider interest in the art community than I would have guessed. Many applicants described their dissatisfaction with the status quo, some in strong terms. We had to close applications after a few weeks because there were so many.
• It's too early to call it, but it seems that both beauty as an unapologetic goal (contra much that is in modernist and contemporary approaches), and ways to channel pre-modern styles into something new for the present era, are of growing interest.
• The awards made me reflect on the perhaps obvious issue of how hard it must be for an artist to persistently do something new: schools, galleries, buyers, etc., all have structurally embedded preferences as well. These individual awards made me wonder what form supporting new clusters could take.
• Architecture seems to me like the discipline most ripe for new ideas. One correspondent observed: "American architects are somewhat constrained by the association with the academy, in addition to the well known regulation issues. There is a tendency to overthink things so that the designs are formally interesting to someone deep in the conversation, but lacking poetry and magic. There are more firms in Europe, South America and beyond that “just do things” (especially in places where it is easier to build)." This was evident in the submissions.
• AI seems to be making people rethink things in a quite fundamental way, just as urbanization/industrialization/popularization of photography did at the end of the 19th century. For some that will mean interesting new forms of AI-augmented art, but the effects of the rethinking will likely be wider.
• Arts funding is clearly as precarious and scarce as ever. That's unfortunate, but it probably also means that individual actors can have meaningful impact, and I encourage others to get involved if interested.
• There's a lot to know that is not written down, and I'm very grateful to those who have helped and advised me along the way.
Patrick Collison retweeted
A day later, our first-ever agent-assisted @atlas company was officially incorporated via MCP. (Fortuitously, it's a startup related to robotics.)
New from @arcinstitute: using the latent space representation of genomes from single-cell life to find new candidate functional RNAs.
I think this is cool because: (1) it uses deep learning and model interpretability to productive ends on a totally different kind of "knowledge"; (2) it shows how agents may be able to accelerate discovery in vast combinatoric spaces; and (3) it's an example of the synergy we'll hopefully see in the coming years between computational techniques and wet lab biology.
Delighted to share a landmark preprint from our lab, using genome language models and AI agents for biological discovery and genome mining!
The stretches of DNA between protein-coding genes are often called the genome’s “dark matter,” but they are far from empty. They encode RNA molecules that sense metabolites, regulate genes, and control some of molecular biology's most important tools (such as programmable genome editors e.g. CRISPR/bridge)
Much of this biology is unexplored. One reason is that RNAs can retain similar structures and functions even as their DNA sequences change dramatically, making their relationships difficult to recognize with conventional computational tools
Patrick Collison retweeted
That means a lot coming from you @eladgil - you set a very high bar for any new @stripepress author with High Growth Handbook!
Patrick Collison retweeted
Delighted to share a landmark preprint from our lab, using genome language models and AI agents for biological discovery and genome mining!
The stretches of DNA between protein-coding genes are often called the genome’s “dark matter,” but they are far from empty. They encode RNA molecules that sense metabolites, regulate genes, and control some of molecular biology's most important tools (such as programmable genome editors e.g. CRISPR/bridge)
Much of this biology is unexplored. One reason is that RNAs can retain similar structures and functions even as their DNA sequences change dramatically, making their relationships difficult to recognize with conventional computational tools
Patrick Collison retweeted
And now you can preorder the NOMAD LETTERS (out December 1!): press.stripe.com/nomad-lette…
For years these letters have circulated (at first, unofficially) among investors, acquiring a devoted readership. We wanted to give them a permanent home in print.
Nick and his partner Qais Zakaria’s record is extraordinary. The letters are the account of how they got there, featuring everything from studying Amazon and Costco (Nomad’s defining investments)—to visiting cement plants in Zimbabwe, and beyond.
They’re candid about their mistakes and curious about the forces that shape investors’ behavior: incentives, psychology, and the wisdom (or foolishness!) of the crowd.
Since closing the fund, they’ve devoted their time to philanthropy, a journey Nick recounts in the lovely foreword he wrote for this edition.
I’m thrilled to continue adding to the investing corner of our catalogue, and I can’t think of a better work to follow Poor Charlie’s Almanack. ❣️
Ben has for many years been the best analyst in tech. I’m very much looking forward to this new @stratechery + @stripe partnership.
stratechery.com/2026/present…
Patrick Collison retweeted
Some big personal news: I'm moving to join Works in Progress as executive editor, starting next month. I have been hoping for an opportunity to work with @bswud and @s8mb for more than a decade, and I'm incredibly excited to finally have one.
WIP is expanding on every front right now. We'll soon begin coverage of business and finance, as well as putting out more reported features. To that end, we'll be hiring more writers and reporters in the year to come. I'm planning to remain based in the US to help build out our presence here.
The print edition of WIP has existed for less than 12 months, but sometime in the next week or so we will reach our 10,000th paying print subscriber. It's a group that now includes people who've been at the highest echelons of government and who run the world's biggest public companies. We’re already on track to 3x that number next year. We'll be in store at Barnes & Noble, Hudson News and independent newsagents next week too.
I think WIP is providing something that people are craving from physical media right now: fewer, extremely well-crafted pieces in a beautifully designed form. Issues now feature an amazing group of columnists, including Tyler Cowen, Dan Wang and Stephen Kotkin. Each edition is better than the last.
You'll see us in more and more places next year too. In January, our new weekly documentary films will launch on YouTube. We're expanding into the events space, with a new series in North America. The sky is the limit from here on out.
These days, I'm struck by how the dominant mood on both sides of the Atlantic toward the other is a kind of pity. Europe frets about the US's supposed slide into autocracy; the US about Europe's pusillanimity and immiseration.
Excellent report on the NSF from Matt Faherty: newscience.org/nsf/. I wish there were more deep investigations and assessments like this of government agencies in the US, the EU, and elsewhere.
Patrick Collison retweeted
potentially a hot take but @stablecoin is still underrated, such a good product and a world class team that just keeps shipping
I very highly recommend visiting the UK's great cathedrals, e.g. Lincoln and Durham. I did so earlier this year and find myself reminiscing about them quite frequently. Some of the most beautiful buildings in the world.
Today is probably a good time to check in on things with @privy_io, which became part of @stripe just over a year ago.
Our acquisition was predicated on three factors: stablecoin growth, self-custody as a key enabler of broader global coverage, and rapidly increasing demand for programmable financial infrastructure. As we said at the time, "money has to reside somewhere, and Privy builds the world's best programmable vaults."
Since then, the Privy team has executed exceptionally well: assets in Privy wallets have grown ~25x, monthly active developers are up ~3x, revenue is up ~9x, and Privy now facilitates nearly $25B of monthly transaction volume. @tryramp, @Deel, @Klarna, @felixpago, @HyperliquidX, and thousands of other businesses are building embedded banking functionality on Privy.
At Stripe, we're deeply integrating Privy into Treasury, @Link, and Connect. In each case, it's accelerating our global expansion, and enabling us to build better functionality faster. (Coming soon: @Link balances.)
We're also seeing that Privy's wallet infrastructure is the ideal substrate for agents to transact and earn -- live today with @merit_systems, @orthogonal_sh, @Nevermined_ai, @prlnet, and more. Developers prefer programmable financial infrastructure, but agents need it. We expect that the agentic economy will continue to grow extremely quickly.
The Privy team has maintained remarkable product velocity, with major launches this year including deposit addresses, earning on Privy balances, digital asset accounts, custodial wallets, and Stripe's own stablecoin cards.
It's also been neat to see how Privy has been accelerated by Stripe, with better onramps, @stablecoin payment rails and licenses, Stripe's fiat capabilities and issuing stack, and integration with @Tempo.
Together, we're building one API for holding stablecoin balances and earning yield, moving money in and out of fiat, and orchestrating spend with cards. We still have a lot of work to do, not least in integrating everything across Privy, Bridge, and the rest of Stripe -- there's been so much feature and functionality expansion that we haven't yet had much time to reconcile everything. Overall, though, I'm very happy with how things are going, and excited by where these capabilities are headed.
If you're interested in working on the future of stablecoins, agentic payments, and crypto's deployment in the real world, you should get in touch with @sternhenri (now leading all of @StripeCrypto) or others on the team.
Stablecoin-backed cards make make global balances instantly usable at 100M+ businesses. We're looking forward to working with @plasma to advance the space.
We're bringing together Stripe's fiat and crypto infrastructure to make it easier for businesses to build stablecoin-backed cards that work across currencies and markets.
More on what we're building with @Plasma,
Patrick Collison retweeted
The future of banking will run on stablecoins.
On Plasma, in partnership with @StripeCrypto.
We're bringing together Stripe's fiat and crypto infrastructure to make it easier for businesses to build stablecoin-backed cards that work across currencies and markets.
More on what we're building with @Plasma,
Patrick Collison retweeted
My full fireside conversation with @patrickc at the Science: A New Golden Age Summit.
We discussed building new institutions for discovery, accelerating scientific progress, and how America can move faster on the hardest scientific challenges.
Collison x Kratsios Fireside
Patrick Collison retweeted
If you’re using stablecoins for real-world use cases, it’ll soon be unthinkable that they aren’t private.
Too much of crypto relies on pseudonymity instead of privacy, especially in the age of AI as it becomes easier to track and correlate transactions onchain.
Tempo has been working on Tempo Zones as a scalable, technically nuanced, and highly practical solution to onchain privacy.
And the first Tempo Zone is now live with Deel, adding privacy to their global contractor payouts.
We all want real-world flows to scale onchain, and privacy is a clear prerequisite to that. The Tempo team has worked hard to craft a practical solution and if you’re interested in learning more, please reach out to the team!
Privacy is live on Tempo.
Tempo Zones let enterprises keep customer stablecoin balances and payments private, with built-in compliance controls and access to global liquidity.
@deel is the first customer with Zones live in production.
New from @stripepress: the definitive guide to sales.
I notice that startups today are scaling sales faster than ever, making it more valuable to get structures and incentives right from the outset.
Out now! Built to Grow: A Handbook for High-Performance Sales Teams, by Stephanie Friedman: press.stripe.com/built-to-gr…
I love all of the books in our catalogue, but I particularly love the turpentine collection: High Growth Handbook, An Elegant Puzzle, Scaling People, and now, Built to Grow!
Building a sales function—especially today—is more of an art than a science. Stephanie has more than 20 years of experience building 100+ person sales teams, and advising some of the fastest-growing companies in the world on how to do the same.
I hope you love it as much as we do.
I’m very biased, but the new @WorksInProgMag is IMO a masterpiece in both design and content.
worksinprogress.co/print/
The @WorksInProgMag team has outdone themselves this time, I didn’t know that was possible
We got flaps and everything!
What a stunning piece of art!


























